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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
coumarin scaffold
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "coumarin scaffold" in MCE Product Catalog:
Target:
Category:
Cat. No.: HY-N3373R
CAS No.: 29748-10-5
Category:
Human Gut Microbiota Metabolites Cornaceae Iridoids Cornus officinalis Sieb. et Zucc. Terpenoids Plants Endogenous metabolite
Target:
Target:
Research Areas:
Pyranocoumarin (Compound 13) is a heterocyclic scaffold (coumarin + pyran ring fusion). Pyranocoumarin inhibits the S-warfarin hydroxylation catalyzed by CYP2C9 .
Cat. No.: HY-W043574
CAS No.: 1484-73-7
Target:
Research Areas:
6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one (Compound 32), a derivative of Coumarin (HY-N0709), acts as a Mcl-1 inhibitor with a Ki of 5.47 μM and an IC50 of 30.88 μM. 6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one is applicable for cancer research .
Cat. No.: HY-L0107V
13,236 compounds
Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Nowadays, new drugs based on Natural products are successfully applied to treat tumors, viral and bacterial diseases, and nervous disorders.
In response to the current drug discovery demand, we created this natural product-like compound library with 13,236 in-stock synthetic compounds similar to natural ones. The library was designed by 2D fingerprint similarity filtering, chemical descriptor-based and natural-likeness scoring selection. These compounds are useful tools for high throughput screening (HTS) and high content screening (HCS) programs.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
