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Results for "

cyclic adenosine monophosphate response element binding protein

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173178
    LNS8801

    		Estrogen Receptor/ERR Cancer
    LNS8801 is an orally active agonist of the G protein-coupled estrogen receptor (GPER). By activating GPER, LNS8801 mediates downstream signaling pathways, such as promoting the production of cyclic adenosine monophosphate (cAMP) and activating the cAMP response element-binding protein (CREB) signaling, thereby exerting anti-tumor activities including inhibiting tumor cell proliferation, inducing cell differentiation, and enhancing tumor immunogenicity. LNS8801 can be used in the research of various cancers (e.g., melanoma, pancreatic cancer, colorectal cancer, lung cancer, etc.) and relevant studies exploring the roles of GPER in normal physiological and pathological processes .
    LNS8801
  • HY-114727
    PDE7-IN-4

    		Phosphodiesterase (PDE) Inflammation/Immunology
    PDE7-IN-4 is a phosphodiesterase 7 (PDE7) inhibitor with activity that increases intracellular cyclic adenosine monophosphate (cAMP) levels. PDE7-IN-4 shows potential inhibitory effects in neurotransmission and anti-inflammatory applications. PDE7-IN-4 exerts its biological activity by acting on the cAMP/cAMP response element binding protein (CREB) pathway. The development of PDE7-IN-4 aims to improve its pharmacokinetic characteristics to more effectively target neurodegenerative diseases and other inflammation-related diseases .
    PDE7-IN-4
  • HY-153948
    CBP-IN-1

    		Histone Acetyltransferase Epigenetic Reader Domain Cancer
    CBP-IN-1 is a potent CBP inhibitor with an IC50 of 1.5 nM. CBP-IN-1 also inhibits CBP BRET and BRD4 (1), with IC50 values of 690 nM and 3100 nM, respectively. CBP-IN-1 can be used in oncology and immuno-oncology research .
    CBP-IN-1

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