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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
cyclin-dependent kinase 2
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "cyclin-dependent kinase 2" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: BIM-X hydrochloride; Ro31-8425 hydrochloride
Research Areas:
Bisindolylmaleimide X hydrochloride(Ro 31-8425 hydrochloride, BIM-X hydrochloride) is a cell-penetrating PKC inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM. Bisindolylmaleimide X hydrochloride inhibits the proliferation of CD4 T cells in vitro. Bisindolylmaleimide X hydrochloride inhibits eNOS-Ser1177 phosphorylation in human embryonic vein endothelial cells. Bisindolylmaleimide X hydrochloride can be used for research on the immune system and cardiovascular diseases .
1
Target:
Research Areas:
GW8510 is a potent cyclin-dependent kinase-2 (CDK2) inhibitor. GW8510 is also a ribonucleotide reductase M2 (RRM2) inhibitor. GW8510 exhibits neuroprotective and anticancer activities .
Cat. No.: HY-170897
CAS No.: 3065079-44-6
CDK2-IN-40 is a CDK2 (Cyclin dependent kinase 2) inhibitor, extracted from patent WO 2024/254245 A1 (Example 1). CDK2-IN-40 inhibits CDK2/Cyclin E1 with an IC50 of ≤ 10 nM .
Cat. No.: HY-168057
CAS No.: 3024971-78-3
PROTAC CDK2 Degrader-1 (Compound 41) is a PROTAC degrader for cyclin-dependent kinase 2 (CDK2). PROTAC CDK2 Degrader-1 inhibits the phosphorylation of RB protein in CDK2 dependent cell line OVCAR3 with an IC50 of 100-500 nM .
Cat. No.: HY-179022
Research Areas:
CAIX/CDK-2-IN-1 is a dual-acting inhibitor of carbonic anhydrase IX (CA IX) and cyclin-dependent kinase-2 (CDK-2) with IC50 values of 0.29 μM and 0.32 μM. The zein nanoparticls of CAIX/CDK-2-IN-1 can induce cancer cells apoptosis. CAIX/CDK-2-IN-1 can be used for the research of cancer, such as lung cancer .
Cat. No.: HY-P70014
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; cyclin dependent kinase 2; Cdc2-Related Protein kinase; Cell Division Protein kinase 2; cyclin-dependent kinase; cyclin-dependent kinase 2; P33(CDK2); P33 Protein kinase
Species:
Human
Source:
E. coli
Cat. No.: HY-P705800
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; cyclin dependent kinase 2; Cdc2-Related Protein kinase; Cell Division Protein kinase 2; cyclin-dependent kinase; cyclin-dependent kinase 2; P33(CDK2); P33 Protein kinase
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-161776
Target:
Research Areas:
P-gp/CDK2-IN-1 (Compound 4j) is an inhibitor for is inhibitor for P-glycoprotein (P-gp) and for cyclin-dependent kinase-2 (CDK2). P-gp/CDK2-IN-1 inhibits the proliferation of cancer cells SW-480 and MCF-7 wit IC50 of 38.6 μM and 26.6 μM. P-gp/CDK2-IN-1 exhibits antioxidant efficacy with EC50 of 580 μM in DPPH experiment .
Cat. No.: HY-P705801
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; cyclin dependent kinase 2; Cdc2-Related Protein kinase; Cell Division Protein kinase 2; cyclin-dependent kinase; cyclin-dependent kinase 2; P33(CDK2); P33 Protein kinase
Species:
Human
Source:
E. coli
Cat. No.: HY-P702675
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; cyclin dependent kinase 2; Cdc2-Related Protein kinase; Cell Division Protein kinase 2; cyclin-dependent kinase; cyclin-dependent kinase 2; P33(CDK2); P33 Protein kinase; CCNA2; cyclin-A2; Prev. CCN1; cyclin A; Prev. CCNA; cyclin A2; cyclin-A
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706158
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; cyclin dependent kinase 2; Cdc2-Related Protein kinase; Cell Division Protein kinase 2; cyclin-dependent kinase; cyclin-dependent kinase 2; P33(CDK2); P33 Protein kinase; CCNE1; cyclin E Variant Ex7del; Prev. CCNE; cyclin Et; G1/S-Specific Cy
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702679
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; cyclin dependent kinase 2; Cdc2-Related Protein kinase; Cell Division Protein kinase 2; cyclin-dependent kinase; cyclin-dependent kinase 2; P33(CDK2); P33 Protein kinase; CCNO; cyclin U; Prev. CCNU; UNG2; UDG2; cyclin Domain Containing; FLJ22
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706199
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHucyclin-dependent kinase 2/CDK2, His; cyclin-dependent kinase 2; Cell Division Protein kinase 2; p33 Protein kinase; CDK2; CDKN2
Species:
Human
Source:
E. coli
Cat. No.: HY-P702676
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; cyclin dependent kinase 2; Cdc2-Related Protein kinase; Cell Division Protein kinase 2; cyclin-dependent kinase; cyclin-dependent kinase 2; P33(CDK2); P33 Protein kinase; CCND1; B-Cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1;
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
