3024971-78-3

PROTAC CDK2 Degrader-1 Chemical Structure
3024971-78-3

Chemical Structure

PROTAC CDK2 Degrader-1

  • CAS No.: 3024971-78-3
  • Formula:C38H46F6N12O4S
  • Molecular Weight:880.91

InChIKey: UWPRKVOQVRSNIB-UHFFFAOYSA-N

SMILES: CN1C2=CC(C3CCN(CC4CCN(S(N5CCC(NC6=NC(C7=CN(CC(F)(F)F)N=C7)=C(C(F)(F)F)C=N6)CC5)(=O)=O)CC4)CC3)=CC=C2C(N8CCC(NC8=O)=O)=N1

Biological Activity: PROTAC CDK2 Degrader-1 (Compound 41) is a PROTAC degrader for cyclin-dependent kinase 2 (CDK2). PROTAC CDK2 Degrader-1 inhibits the phosphorylation of RB protein in CDK2 dependent cell line OVCAR3 with an IC50 of 100-500 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-168057 		PROTAC CDK2 Degrader-1 98.05% PROTAC CDK2 Degrader-1 (Compound 41) is a PROTAC degrader for cyclin-dependent kinase 2 (CDK2). PROTAC CDK2 Degrader-1 inhibits the phosphorylation of RB protein in CDK2 dependent cell line OVCAR3 with an IC50 of 100-500 nM.
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