P-gp/CDK2-IN-1
P-gp/CDK2-IN-1 (Compound 4j) is an inhibitor for is inhibitor for P-glycoprotein (P-gp) and for cyclin-dependent kinase-2 (CDK2). P-gp/CDK2-IN-1 inhibits the proliferation of cancer cells SW-480 and MCF-7 wit IC50 of 38.6 μM and 26.6 μM. P-gp/CDK2-IN-1 exhibits antioxidant efficacy with EC50 of 580 μM in DPPH experiment.
For research use only. We do not sell to patients.
- Formula: C21H23NO8
- Molecular Weight:417.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK2 |
Chemical Information
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Molecular Weight 417.41
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Formula C21H23NO8
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SMILES
O=C(C1=C(N)OC(C=C(C)O2)=C(C2=O)C1C3=CC(OC)=C(OC)C(OC)=C3)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)