CDK2-IN-40
Based on 1 Customer Validation
CDK2-IN-40 is a CDK2 (Cyclin dependent kinase 2) inhibitor, extracted from patent WO 2024/254245 A1 (Example 1). CDK2-IN-40 inhibits CDK2/Cyclin E1 with an IC50 of ≤ 10 nM.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 3065079-44-6
- Formula: C16H21N7O2
- Molecular Weight:343.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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CDK2/cyclinE 10 nM (IC50) |
Chemical Information
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CAS No. 3065079-44-6
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Appearance Solid
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Molecular Weight 343.38
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Formula C16H21N7O2
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Color White to off-white
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SMILES
CC(C)OC1=C(N=CN2C1=NC(NC3CCOCC3)=N2)C4=CNN=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (364.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9122 mL | 14.5611 mL | 29.1223 mL | 72.8056 mL |
| 5 mM | 0.5824 mL | 2.9122 mL | 5.8245 mL | 14.5611 mL | |
| 10 mM | 0.2912 mL | 1.4561 mL | 2.9122 mL | 7.2806 mL | |
| 15 mM | 0.1941 mL | 0.9707 mL | 1.9415 mL | 4.8537 mL | |
| 20 mM | 0.1456 mL | 0.7281 mL | 1.4561 mL | 3.6403 mL | |
| 25 mM | 0.1165 mL | 0.5824 mL | 1.1649 mL | 2.9122 mL | |
| 30 mM | 0.0971 mL | 0.4854 mL | 0.9707 mL | 2.4269 mL | |
| 40 mM | 0.0728 mL | 0.3640 mL | 0.7281 mL | 1.8201 mL | |
| 50 mM | 0.0582 mL | 0.2912 mL | 0.5824 mL | 1.4561 mL | |
| 60 mM | 0.0485 mL | 0.2427 mL | 0.4854 mL | 1.2134 mL | |
| 80 mM | 0.0364 mL | 0.1820 mL | 0.3640 mL | 0.9101 mL | |
| 100 mM | 0.0291 mL | 0.1456 mL | 0.2912 mL | 0.7281 mL |
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