6 Results for "

diabetic eye disease

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "diabetic eye disease" in MCE Product Catalog:

13
SPHINX31
SPHINX31
0 Images
13 Cited Publications
Cat. No.: HY-117661
CAS No.: 1818389-84-2
Target:  

SRPK VEGFR

Research Areas:  

Cardiovascular Disease Cancer

SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease .
loading...
    loading...
View All Sizes
5
Esculin
Esculin
0 Images
5 Cited Publications
Cat. No.: HY-N0188
CAS No.: 531-75-9
Category:  

other families Monophenols Coumarins Phenols Phenylpropanoids Plants Disease Research Fields Cancer

Target:  

p38 MAPK

Esculin is a fluorescent coumarin glucoside, the active ingredient in ash bark. Esculin has antidiabetic effects, improves cognitive impairment in experimental diabetic nephropathy (DN) via the MAPK signaling pathway, and exerts antioxidant stress and anti-inflammatory effects. Esculin also has anticancer, antibacterial, antiviral, neuroprotective, antithrombotic, and therapeutic properties for eye diseases .
loading...
    loading...
View All Sizes
UBX1325
UBX1325
0 Images
Cat. No.: HY-150069
CAS No.: 2271269-01-1
Purity:  99.16%
Target:  

Bcl-2 Family Apoptosis

Research Areas:  

Metabolic Disease

UBX1325 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells. UBX1325 is a potent anti-aging agent that can be used in studies of age-related eye diseases such as diabetic macular oedema (DME), age-related macular degeneration (AMD) and diabetic retinopathy (DR) .
loading...
    loading...
View All Sizes
Conbercept
Conbercept
0 Images
Cat. No.: HY-P99830
CAS No.: 1227158-72-6
Synonyms: KH902

Target:  

VEGFR TNF Receptor Interleukin Related

Research Areas:  

Cardiovascular Disease Inflammation/Immunology Cancer

Conbercept (KH902) is a recombinant fusion protein composed of VEGFR-1 (second domain) and VEGFR-2 (third and fourth domains) regions fused to human IgG1 Fc. Conbercept is a VEGF inhibitor (IC50 = 8.8 pM) and is a soluble receptor decoy that blocks all isoforms of VEGF-A (Kd = 0.5 pM), VEGF-B (Kd = 8 pM), VEGF-C, and PlGF (Kd = 5 pM). Conbercept has anti-inflammatory effects, can lower the levels of VEGF, TNF-α and IL-6, and reduce the infiltration of inflammatory cells. Conbercept decreases tumor growth in several oncology studies. Conbercept can be used for various eye diseases such as polypoidal choroidal vasculopathy (PCV), diabetic macular edema (DME) and pathologic myopia choroidal neovascularization (pmCNV) .
loading...
    loading...
View All Sizes
Esculin (Standard)
Esculin (Standard)
0 Images
Cat. No.: HY-N0188R
CAS No.: 531-75-9
Category:  

other families Monophenols Coumarins Phenols Phenylpropanoids Plants

Target:  

Reference Standards p38 MAPK

Esculin (Standard) is the analytical standard of Esculin. This product is intended for research and analytical applications. Esculin is a fluorescent coumarin glucoside, the active ingredient in ash bark. Esculin has antidiabetic effects, improves cognitive impairment in experimental diabetic nephropathy (DN) via the MAPK signaling pathway, and exerts antioxidant stress and anti-inflammatory effects. Esculin also has anticancer, antibacterial, antiviral, neuroprotective, antithrombotic, and therapeutic properties for eye diseases .
loading...
    loading...
View All Sizes
Lp-PLA2-IN-17
Lp-PLA2-IN-17
0 Images
Cat. No.: HY-160637
CAS No.: 1818842-74-8
Target:  

Phospholipase

Research Areas:  

Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology

Lp-PLA2-IN-17 (Compound 39) is an inhibitor of Lp-PLA2. Lp-PLA2-IN-17 can be used to study disorders involving the hydrolysis of oxidized lipids into two inflammatory substances with the participation of Lp-PLA2 .
loading...
    loading...
View All Sizes
Assay Types