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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
ethanol metabolism
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "ethanol metabolism" in MCE Product Catalog:
Target:
Cat. No.: HY-122373
CAS No.: 58919-61-2
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Coprine is an orally active disulfiram (HY-B0240)-like component and an inhibitor of aldehyde dehydrogenase. Coprine is isolated from Coprinus atranentarius. Coprine inhibits low Km aldehyde dehydrogenase in rat liver and increases blood acetaldehyde levels during in vivo ethanol metabolism. Coprine does not inhibit semi-purified low Km aldehyde dehydrogenase from rat liver in vitro. Coprine can be used in studies related to alcoholism .
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Glucoamylase, Rhizopus sp. (Amyloglucosidase, Rhizopus sp.) is a starch-hydrolyzing enzyme with high catalytic efficiency towards soluble starch and raw starch. Glucoamylase, Rhizopus sp. hydrolyzes α-1,4 and α-1,6 glycosidic linkages in starch and similar substrates, and primarily releases β-glucose molecules from the non-reducing ends. Glucoamylase, Rhizopus sp. participates in glycogen metabolism and is associated with type II glycogen storage disease. Glucoamylase, Rhizopus sp. converts starch into glucose, and is applicable to the industrial production of high-fructose syrup, ethanol and other fermented products .
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Aldehyde Dehydrogenase Isobutyramide is an orally active liver alcohol dehydrogenase (LADH2) inhibitor. Isobutyramide inhibits ethanol metabolism and enhances differentiation-related gene expression, inducing cell cycle arrest and significantly reducing the growth rate of prostate cancer cells (LNCaP). Isobutyramide is promising for research of advanced prostate cancer .
Cat. No.: HY-W129199
CAS No.: 591-64-0
Synonyms: Calcium levulinate
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Calcium 4-Oxopentanoate (levulinic acid calcium) is an effective oral calcium supplement and is commonly used as a food additive. Calcium 4-Oxopentanoate can be reduced in the liver to 4-hydroxypentanoate (HY-W107263), and ethanol enhances this reduction process. Calcium 4-Oxopentanoate can be used for studies on calcium deficiency .
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Methyl benzyl sulfoxide is an uncompetitive inhibitor of horse liver alcohol dehydrogenase with a Ki of 5.0 mM. Methyl benzyl sulfoxide inhibits ethanol metabolism in rats .
Cat. No.: HY-154792
CAS No.: 115621-24-4
Synonyms: PCA
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Pyrrolidone carboxylic acid (PCA) is one of the main components (accounting for approximately 12%) of natural moisturizing factors (NMF) in the mammalian epidermal stratum corneum, and it is produced by the degradation of filaggrin. It exhibits multiple biological activities such as skin moisturization, central GABA release, anxiolysis, and auxiliary ethanol metabolism. The content of Pyrrolidone carboxylic acid correlates with the clinical severity of atopic dermatitis lesions, skin barrier function, and inflammation levels, and shows a negative correlation with the expression of TNF-α and IL-13. Pyrrolidone carboxylic acid can serve as a key skin biomarker for skin barrier function and health .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
