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Results for "

flavescens

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) AP-1 (1) Apoptosis (10) Autophagy (1) Bacterial (3) Beta-secretase (1) Carboxylesterase (CES) (1) Cytochrome P450 (1) ERK (2) Fungal (2) HBV (1) Indoleamine 2,3-Dioxygenase (IDO) (1) Interleukin Related (1) Isotope-Labeled Compounds (1) JNK (1) mTOR (1) NF-κB (4) NOD-like Receptor (NLR) (2) p38 MAPK (1) Phosphodiesterase (PDE) (2) RANKL/RANK (1) Reference Standards (5) RSV (1) TGF-beta/Smad (3) TNF Receptor (2) Tyrosinase (4) β-glucuronidase (1)
By Research Areas:	Cancer (14) Cardiovascular Disease (2) Infection (11) Inflammation/Immunology (12) Metabolic Disease (4)

By Targets:

AMPK (1)

AP-1 (1)

Apoptosis (10)

Autophagy (1)

Bacterial (3)

Beta-secretase (1)

Carboxylesterase (CES) (1)

Cytochrome P450 (1)

ERK (2)

Fungal (2)

HBV (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

Interleukin Related (1)

Isotope-Labeled Compounds (1)

JNK (1)

mTOR (1)

NF-κB (4)

NOD-like Receptor (NLR) (2)

p38 MAPK (1)

Phosphodiesterase (PDE) (2)

RANKL/RANK (1)

Reference Standards (5)

RSV (1)

TGF-beta/Smad (3)

TNF Receptor (2)

Tyrosinase (4)

β-glucuronidase (1)

By Research Areas:

Cancer (14)

Cardiovascular Disease (2)

Infection (11)

Inflammation/Immunology (12)

Metabolic Disease (4)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0158

Oxymatrine Maximum Cited Publications 20 Publications Verification	TGF-beta/Smad Apoptosis	Infection Inflammation/Immunology Cancer
Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection .

HY-N1231

Sophoraflavanone G 3 Publications Verification Kushenol F	Apoptosis	Cancer
Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N0616

Trifolirhizin	Tyrosinase TNF Receptor Bacterial Apoptosis Autophagy AMPK mTOR ERK NF-κB	Infection Metabolic Disease Inflammation/Immunology Cancer
Trifolirhizin is a pterocarpan flavonoid found in the roots of Sophora flavescens. Trifolirhizin is a tyrosinase inhibitor with an IC₅₀ value of 506.77 μM. Trifolirhizin reduces intracellular melanin production and modulates multiple signaling pathways including NFκB-MAPK, AMPK/mTOR, PI3K/Akt, MAPK-NFATc1 and EGFR-MAPK. Trifolirhizin targets biological molecules including PTK6 and COX-2, inhibits the activities of hyaluronidase, collagenase and elastase, induces apoptosis, autophagy and cell cycle arrest, and suppresses the proliferation, migration and invasion of cancer cells. Trifolirhizin exerts diverse pharmacological effects including anti-inflammatory, anti-asthmatic, bone-protective, renoprotective, antibacterial, antifungal, hepatoprotective, antiplatelet, estrogenic and wound-healing activities. Trifolirhizin can be used to investigate a broad range of malignant, inflammatory, metabolic and infectious disorders .

HY-N1373

Sophoridine 5+ Cited Publications	Apoptosis	Cancer
Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N6051

(-)-Maackiain	Fungal NOD-like Receptor (NLR) NF-κB	Infection Inflammation/Immunology
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .

HY-N2463

Kushenol E 1 Publications Verification	Indoleamine 2,3-Dioxygenase (IDO)	Cancer
Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC₅₀ of 7.7 µM and a K_i of 9.5 µM, has anti-tumor activity .

HY-N1746

(2S)-2'-Methoxykurarinone 2'-O-Methylkurarinone	RANKL/RANK	Metabolic Disease Inflammation/Immunology Cancer
(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells .

HY-N6044

Isoanhydroicaritin	Others	Others
Isoanhydroicaritin is a flavonoid isolated from the dried root of S. flavescens .

HY-N8097

Kushenol W	Bacterial	Infection
Kushenol W is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol W has antimicrobial effect, with a MIC of 10 μg/mL for Staphylococcus aureus .

HY-N8092

Kushenol B	Phosphodiesterase (PDE)	Infection Inflammation/Immunology
Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities . Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC₅₀ of 31 µM .

HY-108966

Kushenol C	Beta-secretase	Inflammation/Immunology
Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC₅₀ of 5.45 µM .

HY-N8228

17-Hydroxyneomatrine	Bacterial	Infection Inflammation/Immunology Cancer
17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions .

HY-121381

Kuraridine	Phosphodiesterase (PDE)	Others
Kuraridine is a prenylated flavonol extract from the roots of Sophora flavescens. Kuraridine has an inhibitory effect on cGMP specific phosphodiesterase type 5 (PDE5) (IC₅₀=0.64 μM) .

HY-N2286

Kushenol I 1 Publications Verification	Others	Inflammation/Immunology
Kushenol I is a natural compound isolated from the roots of Sophora flavescens .

HY-N6051R

(-)-Maackiain (Standard)	Reference Standards Fungal NOD-like Receptor (NLR) NF-κB	Infection Inflammation/Immunology
(-)-Maackiain (Standard) is the analytical standard of (-)-Maackiain. This product is intended for research and analytical applications. (-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .

HY-N8095

Kushenol N	Others	Cardiovascular Disease
Kushenol N is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol N has anti-allergic and vasorelaxation activities .

HY-N3413

Kushenol X	Carboxylesterase (CES) β-glucuronidase	Metabolic Disease
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC₅₀s of 2.07 μM and 3.05 μM, respectively .

HY-126033

Sophoranol	HBV RSV	Infection
Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC₅₀ of 10.4 μg/mL .

HY-N1373A

d-Sophoridine (+)-Sophoridine	Apoptosis	Cancer
d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N10787

Methylkushenol C	Others	Others
Methylkushenol C is a phenolic substance. Methylkushenol C can be isolated from Sophora flavescens .

HY-N2847

alpha-Isowighteone	Others	Others
alpha-Isowighteone is a Flavonoids product that can be isolated from the roots of Sophora flavescens .

HY-122933

Kurarinol	Tyrosinase Apoptosis	Cardiovascular Disease Cancer
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC₅₀ of 0.1 μM for mushroom tyrosinase .

HY-N8094

Kushenol M	Cytochrome P450	Others
Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC₅₀ values of 1.29 μM for CYP3A4 in human liver microsomes .

HY-N5143

(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone	Others	Others
(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is isolated from the roots of Sophora flavescens .

HY-N3414

Kushenol L	Others	Metabolic Disease
Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects .

HY-N0616R

Trifolirhizin (Standard)	TNF Receptor Reference Standards Tyrosinase	Inflammation/Immunology Cancer
Trifolirhizin (Standard) is the analytical standard of Trifolirhizin. This product is intended for research and analytical applications. Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC₅₀ of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .

HY-N1373R

Sophoridine (Standard)	Reference Standards Apoptosis	Cancer
Sophoridine (Standard) is the analytical standard of Sophoridine. This product is intended for research and analytical applications. Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0158R

Oxymatrine (Standard)	Reference Standards TGF-beta/Smad Apoptosis	Infection Inflammation/Immunology Cancer
Oxymatrine (Standard) is the analytical standard of Oxymatrine. This product is intended for research and analytical applications. Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.

HY-N1231R

Sophoraflavanone G (Standard) Kushenol F (Standard)	Reference Standards Apoptosis	Cancer
Sophoraflavanone G (Standard) is the analytical standard of Sophoraflavanone G. This product is intended for research and analytical applications. Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-W750902

Oxymatrine-d3	Isotope-Labeled Compounds TGF-beta/Smad Apoptosis	Infection Inflammation/Immunology Cancer
Oxymatrine-d₃ is the deuterium labeled Oxymatrine (HY-N0158). Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection .

HY-N9548

6'-Malonyltrifolirhizin Trifolirhizin 6''-O-malonate	Others	Others
6'-Malonyltrifolirhizin (Trifolirhizin 6''-O-malonate) is a malonylated pterocarpan glucoside that can be isolated both from the roots and callus cultures of Sophora flavescens* var. angustifolia* .

HY-N18197

Norkurarinol	Tyrosinase NF-κB AP-1 Interleukin Related p38 MAPK JNK ERK	Infection
Norkurarinol is a prenylated flavonoid. Norkurarinol can be isolated from Sophora flavescens. Norkurarinol potently inhibits mushroom Tyrosinase DOPA oxidase activity with an IC₅₀ of 2.1 μM. Norkurarinol inhibits poly(I:C)-induced NF-κB/AP-1 activation. Norkurarinol inhibits pro-inflammatory cytokines (TNF-α, IL-6). Norkurarinol inhibits phosphorylation of p38, JNK, and ERK1/2. Norkurarinol increases phosphorylation of IRF3. Norkurarinol has antiviral activity against Rotavirus KJ56-1

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0158

Oxymatrine Maximum Cited Publications 20 Publications Verification	Infection Alkaloids Piperidine Alkaloids Classification of Application Fields Leguminosae Sophora flavescens Aiton Plants Inflammation/Immunology Disease Research Fields Source Classification	TGF-beta/Smad Apoptosis
Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection .

HY-N1231

Sophoraflavanone G 3 Publications Verification Kushenol F	Flavonoids Classification of Application Fields Leguminosae Flavonones Phenols Polyphenols Sophora flavescens Aiton Plants Disease Research Fields Source Classification Cancer	Apoptosis
Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N0616

Trifolirhizin	Structural Classification Flavonoids Classification of Application Fields Leguminosae Trifolium pratense Linn. Sophora flavescens Aiton Plants Other Flavonoids Inflammation/Immunology Disease Research Fields Source Classification Cancer	Tyrosinase TNF Receptor Bacterial Apoptosis Autophagy AMPK mTOR ERK NF-κB
Trifolirhizin is a pterocarpan flavonoid found in the roots of Sophora flavescens. Trifolirhizin is a tyrosinase inhibitor with an IC₅₀ value of 506.77 μM. Trifolirhizin reduces intracellular melanin production and modulates multiple signaling pathways including NFκB-MAPK, AMPK/mTOR, PI3K/Akt, MAPK-NFATc1 and EGFR-MAPK. Trifolirhizin targets biological molecules including PTK6 and COX-2, inhibits the activities of hyaluronidase, collagenase and elastase, induces apoptosis, autophagy and cell cycle arrest, and suppresses the proliferation, migration and invasion of cancer cells. Trifolirhizin exerts diverse pharmacological effects including anti-inflammatory, anti-asthmatic, bone-protective, renoprotective, antibacterial, antifungal, hepatoprotective, antiplatelet, estrogenic and wound-healing activities. Trifolirhizin can be used to investigate a broad range of malignant, inflammatory, metabolic and infectious disorders .

HY-N1373

Sophoridine 5+ Cited Publications	Alkaloids Classification of Application Fields Leguminosae Pyridine Alkaloids Sophora flavescens Aiton Plants Disease Research Fields Source Classification Cancer	Apoptosis
Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N6051

(-)-Maackiain	Infection Structural Classification Monophenols Classification of Application Fields Leguminosae Terpenoids Phenols Diterpenoids Sophora flavescens Aiton Plants Disease Research Fields Source Classification	Fungal NOD-like Receptor (NLR) NF-κB
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .

HY-N2463

Kushenol E 1 Publications Verification	Flavonoids Classification of Application Fields Leguminosae Flavonones Phenols Polyphenols Moghania philippinensis (Merr. Et Rolfe) L. Plants Disease Research Fields Cancer Source Classification	Indoleamine 2,3-Dioxygenase (IDO)
Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC₅₀ of 7.7 µM and a K_i of 9.5 µM, has anti-tumor activity .

HY-N1746

(2S)-2'-Methoxykurarinone 2'-O-Methylkurarinone	Flavonoids Classification of Application Fields Leguminosae Flavonones Phenols Polyphenols Metabolic Disease Sophora flavescens Aiton Plants Inflammation/Immunology Disease Research Fields Source Classification	RANKL/RANK
(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells .

HY-N6044

Isoanhydroicaritin	Flavonols Flavonoids Classification of Application Fields Other Diseases Phenols Polyphenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields Source Classification	Others
Isoanhydroicaritin is a flavonoid isolated from the dried root of S. flavescens .

HY-N8097

Kushenol W	Infection Flavonoids Classification of Application Fields Leguminosae Flavonones Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Source Classification	Bacterial
Kushenol W is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol W has antimicrobial effect, with a MIC of 10 μg/mL for Staphylococcus aureus .

HY-N8092

Kushenol B	Flavonoids Classification of Application Fields Leguminosae Flavonones Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology Source Classification	Phosphodiesterase (PDE)
Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities . Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC₅₀ of 31 µM .

HY-108966

Kushenol C	Flavonols Flavonoids Classification of Application Fields Leguminosae Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology Source Classification	Beta-secretase
Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC₅₀ of 5.45 µM .

HY-N8228

17-Hydroxyneomatrine	Alkaloids Leguminosae Other Alkaloids Plants Sophora flavescens Aiton Source Classification	Bacterial
17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions .

HY-121381

Kuraridine	Chalcones Flavonoids Classification of Application Fields Leguminosae Other Diseases Phenols Polyphenols Sophora flavescens Aiton Plants Disease Research Fields Source Classification	Phosphodiesterase (PDE)
Kuraridine is a prenylated flavonol extract from the roots of Sophora flavescens. Kuraridine has an inhibitory effect on cGMP specific phosphodiesterase type 5 (PDE5) (IC₅₀=0.64 μM) .

HY-N2286

Kushenol I 1 Publications Verification	Flavanonols Flavonoids Classification of Application Fields Leguminosae Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology Source Classification	Others
Kushenol I is a natural compound isolated from the roots of Sophora flavescens .

HY-N6051R

(-)-Maackiain (Standard)	Structural Classification Monophenols Leguminosae Terpenoids Phenols Diterpenoids Sophora flavescens Aiton Plants Source Classification	Reference Standards Fungal NOD-like Receptor (NLR) NF-κB
(-)-Maackiain (Standard) is the analytical standard of (-)-Maackiain. This product is intended for research and analytical applications. (-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .

HY-N8095

Kushenol N	Cardiovascular Disease Flavanonols Flavonoids Classification of Application Fields Leguminosae Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Source Classification	Others
Kushenol N is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol N has anti-allergic and vasorelaxation activities .

HY-N3413

Kushenol X	Flavanonols Flavonoids Classification of Application Fields Leguminosae Phenols Polyphenols Metabolic Disease Sophora flavescens Aiton Plants Disease Research Fields Source Classification	Carboxylesterase (CES) β-glucuronidase
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC₅₀s of 2.07 μM and 3.05 μM, respectively .

HY-126033

Sophoranol	Infection Alkaloids Piperidine Alkaloids Classification of Application Fields Leguminosae Plants Sophora flavescens Aiton Disease Research Fields Source Classification	HBV RSV
Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC₅₀ of 10.4 μg/mL .

HY-N1373A

d-Sophoridine (+)-Sophoridine	Alkaloids Leguminosae Other Alkaloids Plants Sophora flavescens Aiton Source Classification	Apoptosis
d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N10787

Methylkushenol C	Flavonoids Leguminosae Plants Sophora flavescens Aiton Isoflavones Source Classification	Others
Methylkushenol C is a phenolic substance. Methylkushenol C can be isolated from Sophora flavescens .

HY-N2847

alpha-Isowighteone	Flavonoids Leguminosae Sophora flavescens Aiton Plants Source Classification	Others
alpha-Isowighteone is a Flavonoids product that can be isolated from the roots of Sophora flavescens .

HY-122933

Kurarinol	Cardiovascular Disease Flavonoids Classification of Application Fields Leguminosae Flavonones Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Source Classification	Tyrosinase Apoptosis
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC₅₀ of 0.1 μM for mushroom tyrosinase .

HY-N8094

Kushenol M	Flavanonols Flavonoids Classification of Application Fields Leguminosae Other Diseases Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Source Classification	Cytochrome P450
Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC₅₀ values of 1.29 μM for CYP3A4 in human liver microsomes .

HY-N5143

(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone	Flavonoids Classification of Application Fields Leguminosae Isoflavanones Other Diseases Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Source Classification	Others
(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is isolated from the roots of Sophora flavescens .

HY-N3414

Kushenol L	Flavanonols Flavonoids Classification of Application Fields Leguminosae Phenols Polyphenols Metabolic Disease Sophora flavescens Aiton Plants Disease Research Fields Source Classification	Others
Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects .

HY-N0616R

Trifolirhizin (Standard)	Structural Classification Flavonoids Leguminosae Trifolium pratense Linn. Sophora flavescens Aiton Plants Other Flavonoids Source Classification	TNF Receptor Reference Standards Tyrosinase
Trifolirhizin (Standard) is the analytical standard of Trifolirhizin. This product is intended for research and analytical applications. Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC₅₀ of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .

HY-N1373R

Sophoridine (Standard)	Alkaloids Structural Classification Leguminosae Pyridine Alkaloids Sophora flavescens Aiton Plants Source Classification	Reference Standards Apoptosis
Sophoridine (Standard) is the analytical standard of Sophoridine. This product is intended for research and analytical applications. Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0158R

Oxymatrine (Standard)	Alkaloids Piperidine Alkaloids Structural Classification Leguminosae Sophora flavescens Aiton Plants Source Classification	Reference Standards TGF-beta/Smad Apoptosis
Oxymatrine (Standard) is the analytical standard of Oxymatrine. This product is intended for research and analytical applications. Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.

HY-N1231R

Sophoraflavanone G (Standard) Kushenol F (Standard)	Structural Classification Flavonoids Leguminosae Flavonones Phenols Polyphenols Sophora flavescens Aiton Plants Source Classification	Reference Standards Apoptosis
Sophoraflavanone G (Standard) is the analytical standard of Sophoraflavanone G. This product is intended for research and analytical applications. Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N9548

6'-Malonyltrifolirhizin Trifolirhizin 6''-O-malonate	Structural Classification Flavonoids Leguminosae Sophora flavescens Aiton Plants Other Flavonoids Source Classification	Others
6'-Malonyltrifolirhizin (Trifolirhizin 6''-O-malonate) is a malonylated pterocarpan glucoside that can be isolated both from the roots and callus cultures of Sophora flavescens* var. angustifolia* .

HY-N18197

Norkurarinol	Structural Classification Flavonoids Leguminosae Flavonones Sophora flavescens Aiton Plants Source Classification	Tyrosinase NF-κB AP-1 Interleukin Related p38 MAPK JNK ERK
Norkurarinol is a prenylated flavonoid. Norkurarinol can be isolated from Sophora flavescens. Norkurarinol potently inhibits mushroom Tyrosinase DOPA oxidase activity with an IC₅₀ of 2.1 μM. Norkurarinol inhibits poly(I:C)-induced NF-κB/AP-1 activation. Norkurarinol inhibits pro-inflammatory cytokines (TNF-α, IL-6). Norkurarinol inhibits phosphorylation of p38, JNK, and ERK1/2. Norkurarinol increases phosphorylation of IRF3. Norkurarinol has antiviral activity against Rotavirus KJ56-1

Cat. No.	Product Name	Chemical Structure

HY-W750902

Oxymatrine-d3

Oxymatrine-d₃ is the deuterium labeled Oxymatrine (HY-N0158). Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection .

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