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Cat. No.: HY-N2463

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Kushenol E

2 Cited Publications

Customer Review

Based on 2 publication(s) in Google Scholar

Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC₅₀ of 7.7 µM and a K_i of 9.5 µM, has anti-tumor activity.

For research use only. We do not sell to patients.

Purity: 95.32%
CAS No.: 99119-72-9
Formula: C₂₅H₂₈O₆
Molecular Weight:424.49

Storage:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Kushenol E Chemical Structure

CAS No.: 99119-72-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms :

Chemical Information

CAS No. 99119-72-9
Appearance Solid
Molecular Weight 424.49
Formula C₂₅H₂₈O₆
Color Off-white to light yellow
SMILES

O=C1C[C@@H](C2=CC=C(O)C=C2O)OC3=C(C/C=C(C)\C)C(O)=C(C/C=C(C)\C)C(O)=C13
Structure Classification
- Flavonoids
- Flavonones
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Publications (2)

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Journal Impact Factor

Phytomedicine

2026 May 25;157:158338.
IET Nanobiotechnol

PLGA-PEG-c(RGDfK)- Kushenol E Micelles With a Therapeutic Potential for Targeting Ovarian Cancer. [Abstract]

2024 Nov 29:2024:7136323. PMID: 39649540

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kwon M, et al. Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1481-1488. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Publications (2)
Purity & Documentation
References

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Kushenol E

Publications Citing Use of MedChemExpress (MCE) Kushenol E

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms