Sophoraflavanone G
Based on 3 publication(s) in Google Scholar
Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways.
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 97938-30-2
- Formula: C25H28O6
- Molecular Weight:424.49
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Sophoraflavanone G
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Biological Activity
IC50: 29.7 μM (MDA-MB-231 cell)[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
202.07 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 552.97 +/-106.74 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 552.97 +/-106.74 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
21.28 μM
Compound: SFG
|
Cytotoxicity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
|
[PMID: 34496204] |
| A549 | IC50 |
212.41 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 1625.4 +/-413.42 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 1625.4 +/-413.42 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
26.19 μM
Compound: SFG
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
|
[PMID: 34496204] |
| A549 | IC50 |
318.48 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 376.13 +/-60.17 nM)
Chemo-sensitizing activity against human A549 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 376.13 +/-60.17 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
329.75 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 376.13 +/-60.17 nM)
Chemo-sensitizing activity against human A549 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 376.13 +/-60.17 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
382.31 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 376.13 +/-60.17 nM)
Chemo-sensitizing activity against human A549 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 376.13 +/-60.17 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
397.71 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 1162.92 +/-250.73 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 1162.92 +/-250.73 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
403.35 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb =555.44 +/-125.7 nM)
Chemo-sensitizing activity against human A549 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb =555.44 +/-125.7 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
46.29 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 82.47 +/-24.25 nM)
Chemo-sensitizing activity against human A549 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 82.47 +/-24.25 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
471.59 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb =555.44 +/-125.7 nM)
Chemo-sensitizing activity against human A549 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb =555.44 +/-125.7 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
509.94 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb =555.44 +/-125.7 nM)
Chemo-sensitizing activity against human A549 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb =555.44 +/-125.7 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
52.61 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 82.47 +/-24.25 nM)
Chemo-sensitizing activity against human A549 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 82.47 +/-24.25 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
60.52 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 552.97 +/-106.74 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 552.97 +/-106.74 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
603.57 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 1625.4 +/-413.42 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 1625.4 +/-413.42 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
629.51 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 1162.92 +/-250.73 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 1162.92 +/-250.73 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
67.97 nM
Compound: SFG
|
Chemo-sensitizing activity against human A549 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 82.47 +/-24.25 nM)
Chemo-sensitizing activity against human A549 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 82.47 +/-24.25 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
692.66 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 1162.92 +/-250.73 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 1162.92 +/-250.73 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
93.7 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 552.97 +/-106.74 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 552.97 +/-106.74 nM)
|
[PMID: 34496204] |
| A549 | IC50 |
980.34 nM
Compound: SFG
|
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 1625.4 +/-413.42 nM)
Chemo-sensitizing activity against becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 1625.4 +/-413.42 nM)
|
[PMID: 34496204] |
| COS-1 | IC50 |
18.7 μM
Compound: 8
|
Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake
Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake
|
[PMID: 17374486] |
| COS-1 | IC50 |
4.1 μM
Compound: 8
|
Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake
Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake
|
[PMID: 17374486] |
| HEK293 | IC50 |
1.04 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 1.31 +/-0.2 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 1.31 +/-0.2 microM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
1.05 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 1.31 +/-0.2 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 1.31 +/-0.2 microM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
1.56 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 1.31 +/-0.2 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 1.31 +/-0.2 microM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
1062.4 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 787.11 +/-227.51 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 787.11 +/-227.51 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
112.05 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 239.91 +/-25 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 239.91 +/-25 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
112.37 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 558.68 +/-81.31 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 558.68 +/-81.31 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
15.23 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 15.36 +/-6.18 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 15.36 +/-6.18 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
15.38 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 15.36 +/-6.18 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 15.36 +/-6.18 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
17.01 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 15.36 +/-6.18 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 15.36 +/-6.18 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
17.86 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 99.55 +/-7.35 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 99.55 +/-7.35 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.28 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 2.29 +/-0.35 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 2.29 +/-0.35 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.4 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 2.74 +/-0.69 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 2.74 +/-0.69 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.48 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.67 +/-0.39 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.67 +/-0.39 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.61 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.67 +/-0.39 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.67 +/-0.39 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.65 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 2.29 +/-0.35 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 2.29 +/-0.35 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.7 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.67 +/-0.39 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.67 +/-0.39 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.76 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 2.78 +/-0.58 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 2.78 +/-0.58 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.83 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 2.78 +/-0.58 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 2.78 +/-0.58 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.86 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 2.74 +/-0.69 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 2.74 +/-0.69 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.95 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 2.74 +/-0.69 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 2.74 +/-0.69 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
2.99 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 2.78 +/-0.58 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 2.78 +/-0.58 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
238.94 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 558.68 +/-81.31 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 558.68 +/-81.31 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
3.59 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 2.29 +/-0.35 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 2.29 +/-0.35 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
31.5 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 99.55 +/-7.35 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 99.55 +/-7.35 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
314.87 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 260 +/-74.23 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 260 +/-74.23 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
323.75 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 558.68 +/-81.31 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 558.68 +/-81.31 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
329.16 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 260 +/-74.23 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 260 +/-74.23 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
35.13 μM
Compound: SFG
|
Cytotoxicity against human HEK293 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human HEK293 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
|
[PMID: 34496204] |
| HEK293 | IC50 |
358.29 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 787.11 +/-227.51 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 787.11 +/-227.51 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
37.55 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 239.91 +/-25 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 239.91 +/-25 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
38.19 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 35.17 +/-8.65 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 35.17 +/-8.65 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
38.88 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 99.55 +/-7.35 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 99.55 +/-7.35 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
40.08 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 35.17 +/-8.65 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 35.17 +/-8.65 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
41.99 nM
Compound: SFG
|
Chemo-sensitizing activity against human HEK293 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 35.17 +/-8.65 nM)
Chemo-sensitizing activity against human HEK293 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 35.17 +/-8.65 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
416.09 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 260 +/-74.23 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 260 +/-74.23 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
49.7 μM
Compound: SFG
|
Cytotoxicity against ABCG2-overexpressing human HEK293/482R cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against ABCG2-overexpressing human HEK293/482R cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
|
[PMID: 34496204] |
| HEK293 | IC50 |
847.09 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 787.11 +/-227.51 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human HEK293/MDR19 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 787.11 +/-227.51 nM)
|
[PMID: 34496204] |
| HEK293 | IC50 |
99.94 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 239.91 +/-25 nM)
Chemo-sensitizing activity against ABCG2-overexpressing human HEK293/482R cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 239.91 +/-25 nM)
|
[PMID: 34496204] |
| HL-60 | IC50 |
12.5 μM
Compound: 3
|
Cytotoxicity against human HL60 cells after 96 hrs by MTT assay
Cytotoxicity against human HL60 cells after 96 hrs by MTT assay
|
[PMID: 10843587] |
| KB 3-1 | IC50 |
0.72 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1.19 +/-0.39 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1.19 +/-0.39 nM)
|
[PMID: 34496204] |
| KB 3-1 | IC50 |
0.97 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1.19 +/-0.39 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1.19 +/-0.39 nM)
|
[PMID: 34496204] |
| KB 3-1 | IC50 |
1.08 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1.19 +/-0.39 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1.19 +/-0.39 nM)
|
[PMID: 34496204] |
| KB 3-1 | IC50 |
12.44 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 13.78 +/-7.63 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 13.78 +/-7.63 nM)
|
[PMID: 34496204] |
| KB 3-1 | IC50 |
13.02 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 13.78 +/-7.63 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 13.78 +/-7.63 nM)
|
[PMID: 34496204] |
| KB 3-1 | IC50 |
13.2 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 13.78 +/-7.63 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 13.78 +/-7.63 nM)
|
[PMID: 34496204] |
| KB 3-1 | IC50 |
2.1 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.29 +/-0.75 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.29 +/-0.75 nM)
|
[PMID: 34496204] |
| KB 3-1 | IC50 |
2.14 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.29 +/-0.75 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.29 +/-0.75 nM)
|
[PMID: 34496204] |
| KB 3-1 | IC50 |
2.6 nM
Compound: SFG
|
Chemo-sensitizing activity against human KB 3-1 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.29 +/-0.75 nM)
Chemo-sensitizing activity against human KB 3-1 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.29 +/-0.75 nM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
1.7 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-expressing human KB-V1 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.73 +/-0.42 microM)
Chemo-sensitizing activity against ABCB1-expressing human KB-V1 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.73 +/-0.42 microM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
1367.2 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1745 +/-293.01 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1745 +/-293.01 nM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
1524.22 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1745 +/-293.01 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1745 +/-293.01 nM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
1724.3 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1745 +/-293.01 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 1745 +/-293.01 nM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
2.32 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-expressing human KB-V1 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.73 +/-0.42 microM)
Chemo-sensitizing activity against ABCB1-expressing human KB-V1 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.73 +/-0.42 microM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
3.08 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-expressing human KB-V1 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.73 +/-0.42 microM)
Chemo-sensitizing activity against ABCB1-expressing human KB-V1 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.73 +/-0.42 microM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
822.27 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 758.22 +/-156.56 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 758.22 +/-156.56 nM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
865.61 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 758.22 +/-156.56 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 758.22 +/-156.56 nM)
|
[PMID: 34496204] |
| KB-V1 | IC50 |
978.02 nM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 758.22 +/-156.56 nM)
Chemo-sensitizing activity against ABCB1-overexpressing human KB-V1 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 758.22 +/-156.56 nM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
3.04 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 2.63 +/-0.62 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 2.63 +/-0.62 microM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
3.37 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 2.63 +/-0.62 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 2.63 +/-0.62 microM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
3.51 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 2.63 +/-0.62 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 2.63 +/-0.62 microM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
4.92 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 7.09 +/-0.89 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 7.09 +/-0.89 microM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
4.95 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 5.57 +/-0.96 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 5.57 +/-0.96 microM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
5.43 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 5.57 +/-0.96 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 5.57 +/-0.96 microM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
5.58 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 5.57 +/-0.96 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 5.57 +/-0.96 microM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
6.18 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 7.09 +/-0.89 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 7.09 +/-0.89 microM)
|
[PMID: 34496204] |
| NCI/ADR-RES | IC50 |
7.04 μM
Compound: SFG
|
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 7.09 +/-0.89 microM)
Chemo-sensitizing activity against ABCB1-overexpressing human NCI/ADR-RES cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 7.09 +/-0.89 microM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
0.43 μM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 4.33 +/-1.18 microM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 4.33 +/-1.18 microM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
1.16 μM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 4.33 +/-1.18 microM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 4.33 +/-1.18 microM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
1.64 μM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 4.33 +/-1.18 microM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 4.33 +/-1.18 microM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
100.27 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 128.27 +/-22.6 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as SN-38 IC50 at 1 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 128.27 +/-22.6 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
127.03 nM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 963.32 +/-120.89 nM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 963.32 +/-120.89 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
130.53 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 279.69 +/-31.94 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 279.69 +/-31.94 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
172.9 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 279.69 +/-31.94 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 279.69 +/-31.94 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
22.12 μM
Compound: SFG
|
Cytotoxicity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
29.32 μM
Compound: SFG
|
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
358.5 nM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 963.32 +/-120.89 nM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 963.32 +/-120.89 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
419.28 nM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460MX20 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 3262.6 +/-811.81 nM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460MX20 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 3262.6 +/-811.81 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
45.02 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 128.27 +/-22.6 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as SN-38 IC50 at 5 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 128.27 +/-22.6 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
451.72 nM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 3262.6 +/-811.81 nM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as topotecan IC50 at 2 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 3262.6 +/-811.81 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
506.03 nM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 963.32 +/-120.89 nM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 963.32 +/-120.89 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
76.5 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 128.27 +/-22.6 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as SN-38 IC50 at 2 uM measured after 72 hrs in presence of SN-38 by CCK8 assay (Rvb = 128.27 +/-22.6 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
8.8 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 20.7 +/-6.32 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as mitoxantrone IC50 at 2 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 20.7 +/-6.32 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
801.14 nM
Compound: SFG
|
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 3262.6 +/-811.81 nM)
Chemo-sensitizing activity against mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as topotecan IC50 at 1 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 3262.6 +/-811.81 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
9.02 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 20.7 +/-6.32 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as mitoxantrone IC50 at 1 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 20.7 +/-6.32 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
9.4 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 20.7 +/-6.32 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as mitoxantrone IC50 at 5 uM measured after 72 hrs in presence of mitoxantrone by CCK8 assay (Rvb = 20.7 +/-6.32 nM)
|
[PMID: 34496204] |
| NCI-H460 | IC50 |
93.49 nM
Compound: SFG
|
Chemo-sensitizing activity against human NCI-H460 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 279.69 +/-31.94 nM)
Chemo-sensitizing activity against human NCI-H460 cells assessed as topotecan IC50 at 5 uM measured after 72 hrs in presence of topotecan by CCK8 assay (Rvb = 279.69 +/-31.94 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
2.4 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.62 +/-0.31 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as paclitaxel IC50 at 5 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.62 +/-0.31 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
2.51 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.62 +/-0.31 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as paclitaxel IC50 at 2 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.62 +/-0.31 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
25.93 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 28.73 +/-10.04 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as colchicine IC50 at 5 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 28.73 +/-10.04 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
28.25 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 28.73 +/-10.04 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as colchicine IC50 at 2 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 28.73 +/-10.04 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
3.09 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.62 +/-0.31 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as paclitaxel IC50 at 1 uM measured after 72 hrs in presence of paclitaxel by CCK8 assay (Rvb = 2.62 +/-0.31 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
3.45 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 6.01 +/-0.77 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as vincristine IC50 at 5 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 6.01 +/-0.77 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
30.24 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 28.73 +/-10.04 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as colchicine IC50 at 1 uM measured after 72 hrs in presence of colchicine by CCK8 assay (Rvb = 28.73 +/-10.04 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
5.73 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 6.01 +/-0.77 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as vincristine IC50 at 1 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 6.01 +/-0.77 nM)
|
[PMID: 34496204] |
| OVCAR-8 | IC50 |
6 nM
Compound: SFG
|
Chemo-sensitizing activity against human OVCAR-8 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 6.01 +/-0.77 nM)
Chemo-sensitizing activity against human OVCAR-8 cells assessed as vincristine IC50 at 2 uM measured after 72 hrs in presence of vincristine by CCK8 assay (Rvb = 6.01 +/-0.77 nM)
|
[PMID: 34496204] |
| RAW264.7 | IC50 |
10.9 μM
Compound: 9
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess method
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess method
|
[PMID: 26073007] |
Sophoraflavanone G (0 -100 μM; 24 hours) decreases the viability of the HL-60 cells?in a dose-dependent manner[1]. Sophoraflavanone G (0 -100 μM; 24 hours) induces HL-60 cell apoptosis, activated caspase-3 and caspase-9, and downregulated Bcl-2 and Bcl-xL. It also upregulates Bax and released cytochrome?c from the mitochondria into the cytoplasm, enabling apoptosis via the mitochondrially-mediated "intrinsic" pathway[1] Sophoraflavanone G (0 -40 μM; 24 hours) inhibits MDA-MB-231 cell viability in a concentration-dependent manner, with an IC50 value of 29.7 ± 5.2 μM[2]<.br>
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 97938-30-2
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Appearance Solid
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Molecular Weight 424.49
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Formula C25H28O6
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Color Off-white to yellow
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SMILES
O=C1C[C@@H](C2=CC=C(O)C=C2O)OC3=C(C[C@H](C(C)=C)C/C=C(C)\C)C(O)=CC(O)=C13
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Synonyms
Kushenol F
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
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Journal Impact Factor
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Most Recent
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Food Chem
Effects of sun drying combined with baking processes on the flavor quality of Chongqing Tuocha raw tea. [Abstract]2025 Dec 30:497:146992. PMID: 41285060 -
Food Chem
Flavonoid-mediated metabolic underpinning quality variation in red bud-sport pear mutants. [Abstract]2025 Oct 15:489:144992. PMID: 40466530 -
Genes (Basel)
2024 Feb 4;15(2):204. PMID: 38397194
Solvent & Solubility
DMSO : 175 mg/mL (412.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (4.90 mM); Clear solution
This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Li ZY, et al. Sophoraflavanone G Induces Apoptosis in Human Leukemia Cells and Blocks MAPK Activation.Am J Chin Med. 2016;44(1):165-76. [Content Brief]
[2]. Huang WC, et al. Sophoraflavanone G from Sophora flavescens induces apoptosis in triple-negative breast cancer cells.Phytomedicine. 2019 Aug;61:152852. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3558 mL | 11.7788 mL | 23.5577 mL | 58.8942 mL |
| 5 mM | 0.4712 mL | 2.3558 mL | 4.7115 mL | 11.7788 mL | |
| 10 mM | 0.2356 mL | 1.1779 mL | 2.3558 mL | 5.8894 mL | |
| 15 mM | 0.1571 mL | 0.7853 mL | 1.5705 mL | 3.9263 mL | |
| 20 mM | 0.1178 mL | 0.5889 mL | 1.1779 mL | 2.9447 mL | |
| 25 mM | 0.0942 mL | 0.4712 mL | 0.9423 mL | 2.3558 mL | |
| 30 mM | 0.0785 mL | 0.3926 mL | 0.7853 mL | 1.9631 mL | |
| 40 mM | 0.0589 mL | 0.2945 mL | 0.5889 mL | 1.4724 mL | |
| 50 mM | 0.0471 mL | 0.2356 mL | 0.4712 mL | 1.1779 mL | |
| 60 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9816 mL | |
| 80 mM | 0.0294 mL | 0.1472 mL | 0.2945 mL | 0.7362 mL | |
| 100 mM | 0.0236 mL | 0.1178 mL | 0.2356 mL | 0.5889 mL |