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Results for "

gallbladder bile

" in MedChemExpress (MCE) Product Catalog:

By Targets:	G protein-coupled Bile Acid Receptor 1 (1) Akt (2) Apoptosis (2) Biochemical Assay Reagents (6) Cholecystokinin Receptor (4) Endogenous Metabolite (3) HMG-CoA Reductase (HMGCR) (1) PI3K (2) Reference Standards (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (2) Endocrinology (1) Infection (2) Inflammation/Immunology (2) Metabolic Disease (7)
Oligonucleotides:	Cholesterol (1)

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Oligonucleotides

Targets Recommended: Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0190

Caerulein Maximum Cited Publications 132 Publications Verification Ceruletide; Cerulein; FI-6934	Cholecystokinin Receptor	Cardiovascular Disease Metabolic Disease
Caerulein is a decapeptide and a potent cholecystokinin receptor agonist. Caerulein is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts .

HY-P0093

Sincalide 4 Publications Verification Cholecystokinin octapeptide; CCK-8; SQ19844	Cholecystokinin Receptor Apoptosis PI3K Akt	Infection Cancer
Sincalide (Cholecystokinin octapeptide, CCK-8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK. Sincalide can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK .

HY-B1292

Iodipamide 1 Publications Verification Adipiodone	Biochemical Assay Reagents	Inflammation/Immunology
Iodipamide (Adipiodone) is an ionic iodinated contrast agent. Iodipamide is used for diagnostic imaging to visualize the bile ducts and gallbladder during X-ray examinations .

HY-P0093A

Sincalide ammonium 4 Publications Verification Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium	Cholecystokinin Receptor Apoptosis PI3K Akt	Infection Cancer
Sincalide ammonium (Cholecystokinin octapeptide ammonium, CCK-8 ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK‐8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide ammonium can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK .

HY-121799A

Taurohyocholic acid sodium salt THCA sodium salt	Endogenous Metabolite	Others
Taurohyocholic acid (THCA) sodium salt is a taurine-conjugated hyocholic acid. Taurohyocholic acid sodium salt is predictor of the efficacy of tyrosine kinase inhibitors combined withPD-1 inhibitors in hepatocellular carcinoma (HCC) .

HY-146453

TGR5 Receptor Agonist 3	G protein-coupled Bile Acid Receptor 1	Metabolic Disease
TGR5 Receptor Agonist 3 (Compound 19) is a soft-agent G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonist with reduced gallbladder-filling effects (favorable gallbladder safety), with EC50s of 16.4 and 209 nM for hTGR5 and mTGR5, respectively.

HY-106380

Glenvastatin HR 780	HMG-CoA Reductase (HMGCR)	Metabolic Disease
Glenvastatin (HR 780) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Glenvastatin can reduces plasma total cholesterol and phospholipid levels and liver cholesterol contents. Glenvastatin does not increase the contents of cholesterol and total bile acid in the gallbladder bile. Glenvastatin can be used for the research of hyperlipemia

HY-107943

Tyropanoate sodium NSC 107434 sodium	Biochemical Assay Reagents	Others
Tyropanoate (NSC 107434) sodium is an orally active contrast agent for the gallbladder. Tyropanoate sodium is absorbed through the intestines and secreted by the liver into the bile. Tyropanoate sodium then concentrates in the gallbladder to form an image that is not transparent to X-rays, enabling visualization of the gallbladder .

HY-158722

Caerulein acetate	Cholecystokinin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology
Caerulein acetate is a decapeptide and a potent cholecystokinin receptor agonist. Ceruletide acetate is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts .

HY-N15784

Tauro-12-oxolithocholanoic acid sodium	Biochemical Assay Reagents	Metabolic Disease
Tauro-12-oxolithocholanoic acid sodium is a bile acid (BA) suitable to investigate BAs and their relatives’ behavior and correlation with liver, gallbladder, and bile ducts diseases.

HY-B1292R

Iodipamide (Standard) Adipiodone (Standard)	Reference Standards	Others
Iodipamide (Standard) is the analytical standard of Iodipamide. This product is intended for research and analytical applications. Iodipamide is an iodine-based contrast agent, mainly used for X-ray imaging, particularly for gallbladder and bile duct imaging ^{[1] ^.}

HY-118311

(Z)-W 3699 (Z)-Probilin; (Z)-Secrebil; (Z)-Piprozolin	Others	Metabolic Disease
(Z)-W 3699 is a potential choleretic. (Z)-W 3699 can increase the solubility of cholesterol in the gallbladder by altering the secretion of micellar bile acids. (Z)-W 3699 can prevent the formation of cholesterol-containing gallstones in dogs.

HY-107962

Iodamide meglumine Renovue 65	Biochemical Assay Reagents	Others
Iodamide meglumine (Renovue 65) is a type of trityl ion contrast agent. Iodamide meglumine can block X-rays and is used in examinations such as cholangiography and cholecystography to display the gallbladder and bile ducts. Iodamide meglumine has the property of renal tubular active secretion. Iodamide meglumine can be used for intravenous urography .

HY-N13266

5β-Cholestane-3α,7α,12α,25,27-pentol	Endogenous Metabolite	Inflammation/Immunology
5β-Cholestane-3α,7α,12α,25,27-pentol is a bile alcohol found in amphibian bile. 5β-Cholestane-3α,7α,12α,25,27-pentol serves as a principal or sole constituent of sulfate-conjugated bile salts in gallbladder bile of the caecilian Dermophis mexicanus. 5β-Cholestane-3α,7α,12α,25,27-pentol appears as a minor constituent in bile of the toad Bufo b. formosus. 5β-Cholestane-3α,7α,12α,25,27-pentol may represent the end product of cholesterol metabolism in the caecilian, as bile acids remain undetected in this organism .

HY-N15768

Tauro-3β,5α,6β-trihydroxycholanoic acid sodium	Biochemical Assay Reagents	Metabolic Disease
Tauro-3β,5α,6β-trihydroxycholanoic acid sodium is a bile acid (BA) suitable to investigate BAs and their relatives’ behavior and correlation with liver, gallbladder, and bile ducts diseases.

HY-B1292B

Iodipamide meglumine Adipiodone meglumine	Biochemical Assay Reagents	Others
Iodipamide (Adipiodone) meglumine is an iodine-based contrast agent, mainly used for X-ray imaging, particularly for gallbladder and bile duct imaging.

HY-186113

Cysteinocholic acid	Endogenous Metabolite	Others
Cysteinocholic acid is a rare cysteine-conjugated bile acid, can be used as a radioprotective agent in biological and chemical scientific research .

Cat. No.	Product Name

HY-L208

Bile Acids Library	61 compounds
Bile acids are a class of amphiphilic molecules derived from the metabolic breakdown of cholesterol, primarily synthesized in the liver, and play a crucial role in the intestines. Based on their structural characteristics, bile acids are mainly divided into two categories: free bile acids (including Cholic acid, Deoxycholic acid, Chenodeoxycholic acid) and conjugated bile acids (including Glycocholic acid, Glycochenodeoxycholic acid, Taurocholic acid, etc.). Bile acids play a significant role in the pathophysiological research of liver and gastrointestinal diseases and are closely associated with the occurrence of metabolic diseases such as obesity, type II diabetes, non-alcoholic fatty liver disease, and atherosclerosis. Bile acids maintain metabolic balance within the body by regulating sugar metabolism, lipid metabolism, and amino acid metabolism, and they influence the activity of metabolism-related enzymes and transporters. In addition, Bile acids can also be used to construct a bile acid metabolism research platform, which helps to delve into the metabolic pathways and dynamic changes of bile acids in living organisms and aids in identifying new biomarkers for certain diseases. MCE included 61 bile acids, including Cholic acid, Deoxycholic acid, Glycocholic acid, etc., which are effective tools for the study of liver and gallbladder diseases.

Bile Acids Library

61 compounds

Bile acids are a class of amphiphilic molecules derived from the metabolic breakdown of cholesterol, primarily synthesized in the liver, and play a crucial role in the intestines. Based on their structural characteristics, bile acids are mainly divided into two categories: free bile acids (including Cholic acid, Deoxycholic acid, Chenodeoxycholic acid) and conjugated bile acids (including Glycocholic acid, Glycochenodeoxycholic acid, Taurocholic acid, etc.). Bile acids play a significant role in the pathophysiological research of liver and gastrointestinal diseases and are closely associated with the occurrence of metabolic diseases such as obesity, type II diabetes, non-alcoholic fatty liver disease, and atherosclerosis. Bile acids maintain metabolic balance within the body by regulating sugar metabolism, lipid metabolism, and amino acid metabolism, and they influence the activity of metabolism-related enzymes and transporters. In addition, Bile acids can also be used to construct a bile acid metabolism research platform, which helps to delve into the metabolic pathways and dynamic changes of bile acids in living organisms and aids in identifying new biomarkers for certain diseases.

MCE included 61 bile acids, including Cholic acid, Deoxycholic acid, Glycocholic acid, etc., which are effective tools for the study of liver and gallbladder diseases.

Cat. No.	Product Name	Target	Research Area