117997-17-8
117997-17-8
Chemical Structure
Taurohyocholic acid sodium salt
Synonym(s): THCA sodium salt
- CAS No.: 117997-17-8
- Formula:C26H44NNaO7S
- Molecular Weight:537.68
InChIKey: NYXROOLWUZIWRB-YOAOXILXSA-M
SMILES: C[C@@]12[C@]3([H])[C@]([C@@H]([C@@H]([C@]1([H])C[C@@H](CC2)O)O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)C
Biological Activity: Taurohyocholic acid (THCA) sodium salt is a taurine-conjugated hyocholic acid. Taurohyocholic acid sodium salt is predictor of the efficacy of tyrosine kinase inhibitors combined withPD-1 inhibitors in hepatocellular carcinoma (HCC)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Taurohyocholic acid sodium salt | 98.08% | Taurohyocholic acid (THCA) sodium salt is a taurine-conjugated hyocholic acid. Taurohyocholic acid sodium salt is predictor of the efficacy of tyrosine kinase inhibitors combined withPD-1 inhibitors in hepatocellular carcinoma (HCC). | ||||||||||||||||||||
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References
- [1]. He J, et al. Semi-Preparative Isolation and Purification of Three Tauro-Conjugated Cholic Acids from Pulvis Fellis Suis by HSCCC Coupled with ELSD Detection. Chromatographia. 2011;73(3-4):361-365. [Content Brief]
- [2]. Chen Y, et al. Taurohyocholic acid acts as a potential predictor of the efficacy of tyrosine kinase inhibitors combined with programmed cell death-1 inhibitors in hepatocellular carcinoma. Front Pharmacol. 2024 Feb 23;15:1364924. [Content Brief]
Keywords
