2643391-08-4
2643391-08-4
Chemical Structure
TGR5 Receptor Agonist 3
- CAS No.: 2643391-08-4
- Formula:C29H27N3O6
- Molecular Weight:513.54
IUPAC Name: ethoxymethyl 5-((3-(4-cyclopropyl-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)pyridin-4-yl)oxy)benzofuran-3-carboxylate
InChIKey: WJLRTDVQPXBODJ-UHFFFAOYSA-N
SMILES: CCOCOC(C1=COC2=C1C=C(C=C2)OC3=C(C=NC=C3)C(N4CCN(C5=C4C=CC=C5)C6CC6)=O)=O
Biological Activity: TGR5 Receptor Agonist 3 (Compound 19) is a soft-agent G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonist with reduced gallbladder-filling effects (favorable gallbladder safety), with EC50s of 16.4 and 209 nM for hTGR5 and mTGR5, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TGR5 Receptor Agonist 3 | 95.0% | TGR5 Receptor Agonist 3 (Compound 19) is a soft-agent G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonist with reduced gallbladder-filling effects (favorable gallbladder safety), with EC50s of 16.4 and 209 nM for hTGR5 and mTGR5, respectively. | ||||||||||||||||||||
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