122254-45-9
Chemical Structure
Glenvastatin
Synonym(s): HR 780
- CAS No.: 122254-45-9
- Formula:C27H26FNO3
- Molecular Weight:431.50
IUPAC Name: (4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-2-isopropyl-6-phenylpyridin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one
InChIKey: LJIZUXQINHXGAO-ITWZMISCSA-N
SMILES: O[C@@H](CC1=O)C[C@H](O1)/C=C/C2=C(C(C)C)N=C(C3=CC=CC=C3)C=C2C4=CC=C(F)C=C4
Biological Activity: Glenvastatin (HR 780) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Glenvastatin can reduces plasma total cholesterol and phospholipid levels and liver cholesterol contents. Glenvastatin does not increase the contents of cholesterol and total bile acid in the gallbladder bile. Glenvastatin can be used for the research of hyperlipemia[1]
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Glenvastatin | Glenvastatin (HR 780) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Glenvastatin can reduces plasma total cholesterol and phospholipid levels and liver cholesterol contents. Glenvastatin does not increase the contents of cholesterol and total bile acid in the gallbladder bile. Glenvastatin can be used for the research of hyperlipemia | |||||||||||||||||||||
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Keywords
