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Results for "

ganglionic blocking

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (2) Adrenergic Receptor (1) Apoptosis (1) Biochemical Assay Reagents (1) Calcium Channel (4) Caspase (1) Cholinesterase (ChE) (1) Drug Isomer (1) Endogenous Metabolite (1) Fatty Acid Synthase (FASN) (1) Histamine Receptor (5) Integrin (1) Interleukin Related (1) Isotope-Labeled Compounds (2) mAChR (1) nAChR (15) NOD-like Receptor (NLR) (1) Potassium Channel (2) Reference Standards (3) Toll-like Receptor (TLR) (2) TRP Channel (2)
By Research Areas:	Cardiovascular Disease (13) Inflammation/Immunology (5) Metabolic Disease (1) Neurological Disease (31)

By Targets:

Adenosine Receptor (2)

Adrenergic Receptor (1)

Apoptosis (1)

Biochemical Assay Reagents (1)

Calcium Channel (4)

Caspase (1)

Cholinesterase (ChE) (1)

Drug Isomer (1)

Endogenous Metabolite (1)

Fatty Acid Synthase (FASN) (1)

Histamine Receptor (5)

Integrin (1)

Interleukin Related (1)

Isotope-Labeled Compounds (2)

mAChR (1)

nAChR (15)

NOD-like Receptor (NLR) (1)

Potassium Channel (2)

Reference Standards (3)

Toll-like Receptor (TLR) (2)

TRP Channel (2)

By Research Areas:

Cardiovascular Disease (13)

Inflammation/Immunology (5)

Metabolic Disease (1)

Neurological Disease (31)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1395

Mecamylamine hydrochloride 5 Publications Verification	nAChR Histamine Receptor	Cardiovascular Disease Neurological Disease
Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine hydrochloride is also a ganglionic blocker. Mecamylamine hydrochloride can across the blood-brain barrier. Mecamylamine hydrochloride can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area .

HY-W008350

(+)-Sparteine 1 Publications Verification Pachycarpine	nAChR	Neurological Disease
(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

HY-N0340

Scopolamine butylbromide 1 Publications Verification Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide	mAChR	Neurological Disease Inflammation/Immunology
Scopolamine butylbromide (Hyoscine butylbromide) is an orally active anticholinergic agent and spasmolytic. Scopolamine butylbromide binds with high affinity to rat cardiac M2 (K_i 83 nmol/L), hM2 (K_i 233 nmol/L), rat intestinal M3 (K_i 290 nmol/L) and hM3 (K_i 643 nmol/L) muscarinic receptors. Scopolamine butylbromide exerts a dose-dependent antagonistic effect on Carbachol-induced gastrointestinal smooth muscle spasm. Scopolamine butylbromide can be used for the research of abdominal colic and pain associated with gastrointestinal spasm, functional abdominal pain, chronic gastropathy and gastric ulcer .

HY-121119

MRS 1523 5 Publications Verification	Adenosine Receptor Calcium Channel	Cardiovascular Disease Neurological Disease Inflammation/Immunology
MRS 1523 is a potent and selective adenosine A₃ receptor antagonist with K_i values of 18.9 nM and 113 nM for human and rat A₃ receptors, respectively. In rat this corresponds to selectivities of 140- and 18-fold vs A₁ and A_2A receptors, respectively. MRS 1523 can exert antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons .

HY-B1382

Pempidine 1,2,2,6,6-Pentamethylpiperidine	nAChR	Cardiovascular Disease Neurological Disease
Pempidine (1,2,2,6,6-Pentamethylpiperidine) is an orally active ganglionic blocking agent used in hypertension-related conditions. Pempidine is a nicotinic receptor blocker. Pempidine can antagonize the nicotine-induced increase of the striatal dopamine (DA) in vitro .

HY-120751

TROX-1	Calcium Channel	Neurological Disease
TROX-1 is a selective, orally active and brain-penetrant N-type calcium channel (Cav2.2) inhibitor with an IC₅₀ value of 0.11 μM. TROX-1 exerts state-dependent and use-dependent inhibition, preferentially targets open/inactivated channels, blocks depolarization-associated calcium influx, and fully blocks calcium influx in rat dorsal root ganglion neurons. TROX-1 reverses inflammatory-induced hyperalgesia, nerve injury-induced allodynia. TROX-1 can be used for the research of pain .

HY-B0530

Azacyclonol 1 Publications Verification γ-pipradol	Histamine Receptor	Neurological Disease
Azacyclonol (γ-pipradol), a metabolite of Terfenadine, is a central depressant agent. Azacyclonol is a ganglion-blocking agent. Azacyclonol can be used to diminish psychoses-induced hallucinations .

HY-101347

Chlorisondamine diiodide	nAChR	Neurological Disease
Chlorisondamine (diiodide) is a potent nicotinic acetylcholine receptor (nAChR) antagonist and a ganglion blocker. Chlorisondamine antagonizes some of nicotine's central actions in a potent, long-lasting and pharmacologically selective way .

HY-119926

13-Hydroxylupanine Hydroxylupanine	Integrin	Cardiovascular Disease Neurological Disease
13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .

HY-P10227

Xelafaslatide ONL-1204	Fatty Acid Synthase (FASN) Apoptosis Interleukin Related Toll-like Receptor (TLR) NOD-like Receptor (NLR) Caspase	Neurological Disease
Xelafaslatide (ONL-1204) is a Fas receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma .

HY-B1219

Pentolinium tartrate	nAChR	Neurological Disease
Pentolinium tartrate is a **ganglionic blocking** agent. Pentolinium tartrate lowers blood pressure and permits regression of the signs and symptoms associated with severe hypertension .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Neurological Disease Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

HY-B1395A

Mecamylamine	nAChR Histamine Receptor	Cardiovascular Disease Neurological Disease
Mecamylamine is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine is also a ganglionic blocker. Mecamylamine can across the blood-brain barrier. Mecamylamine can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area .

HY-N0789

Delsoline	Others	Neurological Disease Metabolic Disease
Delsoline, a major alkaloid of Delphinium anthriscifolium Hance, has both a curare-like effect and a ganglion-blocking effect and is used to relieve muscle tension or hyperkinesia. D. anthriscifolium Hance has effects of dispelling wind and dampness, activating collaterals, and relieving pains and is used to treat rheumatism, hemiplegia, indigestion, and cough .

HY-B1304A

(+)-Sparteine sulfate pentahydrate 1 Publications Verification (+)-Lupinidine sulfate pentahydrate	nAChR	Neurological Disease
(+)-sparteine (sulfate pentahydrate) is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons .

HY-164183

Trimethaphan bromide	Adrenergic Receptor	Cardiovascular Disease
Trimethaphan bromide is a ganglionic blocking agent and can be used for study of hypertension .

HY-167741

Chlorisondamine	nAChR	Cardiovascular Disease Neurological Disease
Chlorisondamine is a nicotinic antagonist that acts as a ganglionic blocker and has been utilized to evaluate the neurogenic contributions to blood pressure and sympathetic vasomotor tone in animal models. Chlorisondamine has demonstrated antihypertensive properties, primarily being assessed through its effects on blood pressure, cardiac output, and heart rate in various experimental settings, particularly in mice.

HY-N9949

Sparteine Lupinidine	nAChR	Neurological Disease
Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor) .

HY-P3071A

ShK toxin TFA Stichodactyla helianthus neurotoxin TFA	Potassium Channel	Neurological Disease Inflammation/Immunology
ShK toxin TFA (Stichodactyla helianthus neurotoxin TFA) is a neurotoxin. ShK toxin TFA blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin TFA can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin TFA competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin TFA suppresses K ⁺ currents in cultured rat dorsal root ganglion neurons. ShK toxin TFA also inhibits T lymphocyte proliferation .

HY-105749

Pentamethonium bromide	Endogenous Metabolite	Neurological Disease
Pentamethonium bromide is a ganglion blocker that exhibits antihypertensive and vasodilatory activities .

HY-B1661

Hexamethonium chloride Hexone chloride	Biochemical Assay Reagents	Cardiovascular Disease Others
Hexamethonium Chloride Dihydrate is a synthetic organic compound commonly used as a ganglion blocking agent, which means it blocks the transmission of nerve impulses between ganglion cells in the autonomic nervous system. Hexamethonium Chloride Dihydrate is used in various medical applications such as lowering blood pressure or inhibiting certain types of neuropathic pain. It works by inhibiting the release of acetylcholine, a neurotransmitter that plays a key role in regulating many bodily functions.

HY-B1552B

Benzoquinonium dibromide	nAChR	Neurological Disease
Benzoquinonium dibromide is a nicotinic acetylcholine receptors (nAChRs) antagonist, with an IC₅₀ of 0.46 μM. Benzoquinonium dibromide can block neuromuscular and ganglionic transmission .

HY-119926A

13-Hydroxylupanine hydrochloride Hydroxylupanine hydrochloride	Others	Cardiovascular Disease Neurological Disease
13-Hydroxylupanine Hydroxylupanine is the typical alkaloid profile of sweet lupins. 13-Hydroxylupanine Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .

HY-B1382A

Pempidine hydrochloride 1,2,2,6,6-Pentamethylpiperidine hydrochloride	nAChR	Cardiovascular Disease Neurological Disease
Pempidine (1,2,2,6,6-Pentamethylpiperidine) hydrochloride is an orally active ganglionic blocking agent used in the treatment of hypertension. Pempidine hydrochloride blocks the effects of intravenously administered addictive drugs and peripheral vagal nerve stimulation on blood pressure, and reduces the output of acetylcholine .

HY-121122

A778317	TRP Channel	Others
A778317 is a TRPV1 antagonists. A778317 can block changes in intracellular calcium levels mediated by TRPV1 receptors, with a pIC₅₀ value of 8.31. A-778317 can also block the activation of natural rat TRPV1 receptors in dorsal root ganglion neurons by capsaicin and acid .

HY-B0530R

Azacyclonol (Standard) γ-pipradol (Standard)	Reference Standards Histamine Receptor	Neurological Disease
Azacyclonol (Standard) is the analytical standard of Azacyclonol. This product is intended for research and analytical applications. Azacyclonol (γ-pipradol), a metabolite of Terfenadine, is a central depressant agent. Azacyclonol is a ganglion-blocking agent. Azacyclonol can be used to diminish psychoses-induced hallucinations .

HY-B1395S

Mecamylamine-d3 hydrochloride	Isotope-Labeled Compounds nAChR	Neurological Disease
Mecamylamine-d₃ hydrochloride is the deuterium labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier .

HY-B1395R

Mecamylamine hydrochloride (Standard)	Reference Standards nAChR Histamine Receptor	Cardiovascular Disease Neurological Disease
Mecamylamine (hydrochloride) (Standard) is the analytical standard of Mecamylamine (hydrochloride). This product is intended for research and analytical applications. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine hydrochloride is also a ganglionic blocker. Mecamylamine hydrochloride can across the blood-brain barrier. Mecamylamine hydrochloride can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area .

HY-B1395S1

Mecamylamine hydrochloride-13C4,15N	Isotope-Labeled Compounds nAChR	Neurological Disease
Mecamylamine (hydrochloride)- ¹³C₄, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier .

HY-121119R

MRS 1523 (Standard)	Adenosine Receptor Calcium Channel	Cardiovascular Disease Neurological Disease Inflammation/Immunology
MRS 1523 (Standard) is the analytical standard of MRS 1523. This product is intended for research and analytical applications. MRS 1523 is a potent and selective adenosine A3 receptor antagonist with Ki values of 18.9 nM and 113 nM for human and rat A3 receptors, respectively. In rat this corresponds to selectivities of 140- and 18-fold vs A1 and A2A receptors, respectively. MRS 1523 can exert antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons .

HY-180382

Trimethidinium methosulfate	Cholinesterase (ChE)	Cardiovascular Disease
Trimethidinium methosulfate is an orally active ganglionic blocker with central antihypertensive activity. Trimethidinium methosulfate inhibits the conduction of sympathetic ganglia and reduces vascular contraction. Trimethidinium methosulfate acts on the cerebrovascular motor center and lowers peripheral vascular resistance. Trimethidinium methosulfate has cholinergic nerve inhibitory side effects, but they are relatively mild. Trimethidinium methosulfate can be used in hypertension research .

HY-W008350R

(+)-Sparteine (Standard) Pachycarpine (Standard)	nAChR Reference Standards	Neurological Disease
(+)-Sparteine (Standard) is the analytical standard of (+)-Sparteine (HY-W008350). This product is intended for research and analytical applications. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

HY-108459

6-Iodonordihydrocapsaicin	TRP Channel	Neurological Disease
6-Iodonordihydrocapsaicin is a TRPV1 antagonist. 6-Iodonordihydrocapsaicin functionally blocks TRPV1-mediated responses, including capsaicin-induced ion currents in dorsal root ganglion neurons and distension-induced firing of jejunal spinal afferent fibers in mice. 6-Iodonordihydrocapsaicin can be used in the research of visceral pain and anxiety disorders .

HY-120751A

(S)-TROX-1	Drug Isomer Calcium Channel	Neurological Disease
(S)-TROX-1 is the S-enantiomer of TROX-1 (HY-120751). TROX-1 is a selective, orally active and brain-penetrant N-type calcium channel (Cav2.2) inhibitor with an IC₅₀ value of 0.11 μM. TROX-1 exerts state-dependent and use-dependent inhibition, preferentially targets open/inactivated channels, blocks depolarization-associated calcium influx, and fully blocks calcium influx in rat dorsal root ganglion neurons. TROX-1 reverses inflammatory-induced hyperalgesia, nerve injury-induced allodynia. TROX-1 can be used for the research of pain .

HY-182500A

(S,S)-SARM1-IN-9	Toll-like Receptor (TLR)	Neurological Disease
(S,S)-SARM1-IN-9 (Compound MY-13A) is a stereoselective SARM1 inhibitor with covalent binding properties. (S,S)-SARM1-IN-9 covalently modifies Cys311 in the autoregulatory ARM domain of wild-type SARM1, thereby blocking NADase activity, without inhibiting the SARM1 ^C311A or SARM1 ^C311S mutants. (S,S)-SARM1-IN-9 blocks vacor- and vincristine-induced axon degeneration in primary rodent dorsal root ganglion neurons. (S,S)-SARM1-IN-9 can be used for research on axon degeneration-dependent neurological disorders, including chemotherapy-induced peripheral neuropathy .

Cat. No.	Product Name	Type

HY-B1661

Hexamethonium chloride Hexone chloride	Biochemical Assay Reagents
Hexamethonium Chloride Dihydrate is a synthetic organic compound commonly used as a ganglion blocking agent, which means it blocks the transmission of nerve impulses between ganglion cells in the autonomic nervous system. Hexamethonium Chloride Dihydrate is used in various medical applications such as lowering blood pressure or inhibiting certain types of neuropathic pain. It works by inhibiting the release of acetylcholine, a neurotransmitter that plays a key role in regulating many bodily functions.

Hexamethonium chloride

Hexone chloride

Biochemical Assay Reagents

Hexamethonium Chloride Dihydrate is a synthetic organic compound commonly used as a ganglion blocking agent, which means it blocks the transmission of nerve impulses between ganglion cells in the autonomic nervous system. Hexamethonium Chloride Dihydrate is used in various medical applications such as lowering blood pressure or inhibiting certain types of neuropathic pain. It works by inhibiting the release of acetylcholine, a neurotransmitter that plays a key role in regulating many bodily functions.

Cat. No.	Product Name	Target	Research Area

HY-P10227

Xelafaslatide ONL-1204	Fatty Acid Synthase (FASN) Apoptosis Interleukin Related Toll-like Receptor (TLR) NOD-like Receptor (NLR) Caspase	Neurological Disease
Xelafaslatide (ONL-1204) is a Fas receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Neurological Disease Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

HY-P3071A

ShK toxin TFA Stichodactyla helianthus neurotoxin TFA	Potassium Channel	Neurological Disease Inflammation/Immunology
ShK toxin TFA (Stichodactyla helianthus neurotoxin TFA) is a neurotoxin. ShK toxin TFA blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin TFA can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin TFA competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin TFA suppresses K ⁺ currents in cultured rat dorsal root ganglion neurons. ShK toxin TFA also inhibits T lymphocyte proliferation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W008350

(+)-Sparteine 1 Publications Verification Pachycarpine	Alkaloids Piperidine Alkaloids Structural Classification other families Plants Source Classification	nAChR
(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

HY-N0340

Scopolamine butylbromide 1 Publications Verification Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide	Alkaloids Structural Classification Other Alkaloids Datura metel L. Solanaceae Plants Source Classification	mAChR
Scopolamine butylbromide (Hyoscine butylbromide) is an orally active anticholinergic agent and spasmolytic. Scopolamine butylbromide binds with high affinity to rat cardiac M2 (K_i 83 nmol/L), hM2 (K_i 233 nmol/L), rat intestinal M3 (K_i 290 nmol/L) and hM3 (K_i 643 nmol/L) muscarinic receptors. Scopolamine butylbromide exerts a dose-dependent antagonistic effect on Carbachol-induced gastrointestinal smooth muscle spasm. Scopolamine butylbromide can be used for the research of abdominal colic and pain associated with gastrointestinal spasm, functional abdominal pain, chronic gastropathy and gastric ulcer .

HY-N0789

Delsoline	Alkaloids Pyrrole Alkaloids Ranunculaceae Aconitum carmichaeli Debx. Plants Source Classification	Others
Delsoline, a major alkaloid of Delphinium anthriscifolium Hance, has both a curare-like effect and a ganglion-blocking effect and is used to relieve muscle tension or hyperkinesia. D. anthriscifolium Hance has effects of dispelling wind and dampness, activating collaterals, and relieving pains and is used to treat rheumatism, hemiplegia, indigestion, and cough .

HY-B1304A

(+)-Sparteine sulfate pentahydrate 1 Publications Verification (+)-Lupinidine sulfate pentahydrate	Alkaloids Piperidine Alkaloids other families Plants Source Classification	nAChR
(+)-sparteine (sulfate pentahydrate) is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons .

HY-N9949

Sparteine Lupinidine	Structural Classification Alkaloids Piperidine Alkaloids Plants Fabaceae Source Classification Lupinus sulphureus Douglas	nAChR
Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor) .

HY-119926A

13-Hydroxylupanine hydrochloride Hydroxylupanine hydrochloride	Alkaloids Leguminosae Lupinus perennis L. Plants Source Classification	Others
13-Hydroxylupanine Hydroxylupanine is the typical alkaloid profile of sweet lupins. 13-Hydroxylupanine Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .

HY-W008350R

(+)-Sparteine (Standard) Pachycarpine (Standard)	Alkaloids Piperidine Alkaloids Structural Classification other families Plants Source Classification	nAChR Reference Standards
(+)-Sparteine (Standard) is the analytical standard of (+)-Sparteine (HY-W008350). This product is intended for research and analytical applications. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

Cat. No.	Product Name	Chemical Structure

HY-B1395S

Mecamylamine-d3 hydrochloride

Mecamylamine-d₃ hydrochloride is the deuterium labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier .

HY-B1395S1

Mecamylamine hydrochloride-13C4,15N

Mecamylamine (hydrochloride)- ¹³C₄, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier .

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ganglionic blocking

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