1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. nAChR
  3. (+)-Sparteine sulfate pentahydrate

(+)-Sparteine sulfate pentahydrate (Synonyms: (+)-Lupinidine sulfate pentahydrate)

Cat. No.: HY-B1304A
Handling Instructions

(+)-sparteine (sulfate pentahydrate) is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

For research use only. We do not sell to patients.

(+)-Sparteine sulfate pentahydrate Chemical Structure

(+)-Sparteine sulfate pentahydrate Chemical Structure

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

Other Forms of (+)-Sparteine sulfate pentahydrate:

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Description

(+)-sparteine (sulfate pentahydrate) is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons[1].

IC50 & Target

nAChR[1]

In Vitro

(+)-Sparteine (2 μM) (sulfate pentahydrate) reduces the ACh-induced current caused by activation of nicotinic ACh receptors (AChRs) in a voltage-independent manner at membrane potentials of -50 mV to +30 mV, whereas its blocking effect increased at more negative membrane potentials. (+)-sparteine (5 μM and 10 μM) (sulfate pentahydrate) reduces the amplitude of the excitatory postsynaptic currents (EPSC) and the time constant of the EPSC decay[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

422.54

Formula

C₁₅H₃₈N₂O₉S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
(+)-Sparteine sulfate pentahydrate
Cat. No.:
HY-B1304A
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