1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. nAChR

(+)-Sparteine 

Cat. No.: HY-W008350
Handling Instructions

(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

For research use only. We do not sell to patients.

(+)-Sparteine Chemical Structure

(+)-Sparteine Chemical Structure

CAS No. : 492-08-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of (+)-Sparteine:

  • Biological Activity

  • Technical Information

  • References

Description

(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

IC50 & Target

AChR[1]

In Vitro

(+)-Sparteine (2 μM) reduces the ACh-induced current caused by activation of nicotinic AChRs in a voltage-independent manner. (+)-Sparteine (5, 10 μM) reduces the amplitude of the excitatory postsynaptic current (EPSC) and the time constant of the EPSC decay[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2666 mL 21.3329 mL 42.6658 mL
5 mM 0.8533 mL 4.2666 mL 8.5332 mL
10 mM 0.4267 mL 2.1333 mL 4.2666 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

234.38

Formula

C₁₅H₂₆N₂

CAS No.

492-08-0

SMILES

[H][[email protected]]12CCCCN1C[[email protected]]3C[[email protected]@H]2CN4CCCC[[email protected]@]34[H]

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
(+)-Sparteine
Cat. No.:
HY-W008350
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(+)-Sparteine

Cat. No.: HY-W008350