492-08-0
492-08-0
Chemical Structure
(+)-Sparteine
Synonym(s): Pachycarpine
- CAS No.: 492-08-0
- Formula:C15H26N2
- Molecular Weight:234.39
IUPAC Name: (7R,7aR,14R,14aS)-dodecahydro-2H,6H-7,14-methanodipyrido[1,2-a:1',2'-e][1,5]diazocine
InChIKey: SLRCCWJSBJZJBV-TUVASFSCSA-N
SMILES: [H][C@]12CCCCN1C[C@H]3C[C@@H]2CN4CCCC[C@@]34[H]
Biological Activity: (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.
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(+)-Sparteine | 99.87% | (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. | ||||||||||||||||||||
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(+)-Sparteine (Standard) | ≥98% | (+)-Sparteine (Standard) is the analytical standard of (+)-Sparteine (HY-W008350). This product is intended for research and analytical applications. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. | ||||||||||||||||||||
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Leontine | Leontine is a biochemical assay reagent. | |||||||||||||||||||||
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(-)-Sparteine sulfate pentahydrate | (-)-Sparteine sulfate pentahydrate ((-)-Lupinidine sulfate pentahydrate) is a chiral proton base and catalytic promoter. (-)-Sparteine sulfate pentahydrate promotes the enantioselective carbolithiation of cinnamyl derivatives with primary and secondary organolithium reagents. (-)-Sparteine sulfate pentahydrate forms mixed aggregates with lithium halides. As an exogenous chiral base, (-)-Sparteine sulfate pentahydrate deprotonates palladium-bound secondary alcohols, promotes the formation of palladium-alkoxide species, and alters the rate-limiting step of the catalytic cycle, thereby affecting reaction rate and enantioselectivity. | |||||||||||||||||||||
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Allomatrine | 99.98% | Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors. | ||||||||||||||||||||
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Matrine (Standard) | ≥98% | Matrine (Standard) is the analytical standard of Matrine. This product is intended for research and analytical applications. Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI). | ||||||||||||||||||||
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(-)-Sparteine sulfate | (-)-Sparteine sulfate ((-)-Lupinidine sulfate) is a chiral proton base and catalytic promoter. (-)-Sparteine sulfate promotes the enantioselective carbolithiation of cinnamyl derivatives with primary and secondary organolithium reagents. (-)-Sparteine sulfate forms mixed aggregates with lithium halides. As an exogenous chiral base, (-)-Sparteine sulfate deprotonates palladium-bound secondary alcohols, promotes the formation of palladium-alkoxide species, and alters the rate-limiting step of the catalytic cycle, thereby affecting reaction rate and enantioselectivity. | |||||||||||||||||||||
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Lupanine | 98.2% | Lupanine (D-Lupanine) is a natural ketonic derivative of Sparteine (HY-W008350) with a ganglioplegic activity. Lupanine shows binding affinity for nicotinic receptor with a Ki value of 500 nM. | ||||||||||||||||||||
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Lupanine perchlorate | Lupanine (D-Lupanine) perchlorate is a natural ketonic derivative of Sparteine (HY-W008350)with a ganglioplegic activity. Lupanine perchlorate shows binding affinity for nicotinic receptor with a Ki value of 500 nM. | |||||||||||||||||||||
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Lupanine hydrochloride | Lupanine (D-Lupanine) hydrochloride is a natural ketonic derivative of Sparteine (HY-W008350) with a ganglioplegic activity. Lupanine hydrochloride shows binding affinity for nicotinic receptor with a Ki value of 500 nM. | |||||||||||||||||||||
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Sparteine | Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor). | |||||||||||||||||||||
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(-)-Sparteine hydroiodide | (-)-Sparteine hydroiodide ((-)-Lupinidine hydroiodide) is a chiral proton base and catalytic promoter. (-)-Sparteine hydroiodide promotes the enantioselective carbolithiation of cinnamyl derivatives with primary and secondary organolithium reagents. (-)-Sparteine hydroiodide forms mixed aggregates with lithium halides. As an exogenous chiral base, (-)-Sparteine hydroiodide deprotonates palladium-bound secondary alcohols, promotes the formation of palladium-alkoxide species, and alters the rate-limiting step of the catalytic cycle, thereby affecting reaction rate and enantioselectivity. | |||||||||||||||||||||
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