71 Results for "

ginseng

" in MedChemExpress (MCE) Product Catalog:
Products (71)

71 Results for "ginseng" in MCE Product Catalog:

16
Ginsenoside Rb1
Ginsenoside Rb1
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16 Publications Verification
Cat. No.: HY-N0039
CAS No.: 41753-43-9
Synonyms: Gypenoside III
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Araliaceae Cancer

Target:  

Na+/K+ ATPase IRAK NF-κB Autophagy Mitophagy HSV

Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na +, K +-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
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16
Ginsenoside Rg1
Ginsenoside Rg1
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16 Publications Verification
Cat. No.: HY-N0045
CAS No.: 22427-39-0
Synonyms: Panaxoside A; Panaxoside Rg1
Category:  

Panax ginseng C. A. Meyer Triterpenes Neurological Disease Anti-aging Terpenoids Plants Disease Research Fields Araliaceae Cancer

Target:  

Amyloid-β NF-κB Apoptosis

Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.
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11
Ginsenoside Rk1
Ginsenoside Rk1
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11 Cited Publications
Cat. No.: HY-N2515
CAS No.: 494753-69-4
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

NF-κB PI3K JAK Apoptosis

Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures . Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB . Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis . Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway .
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9
20(S)-Ginsenoside Rg3
20(S)-Ginsenoside Rg3
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9 Cited Publications
Cat. No.: HY-N0603
CAS No.: 14197-60-5
Synonyms: 20(S)-Propanaxadiol; S-ginsenoside Rg3
Category:  

Panax ginseng C. A. Meyer Triterpenes Neurological Disease Terpenoids Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

Sodium Channel Potassium Channel NF-κB COX Amyloid-β Endogenous Metabolite

20(S)-Ginsenoside Rg3 is the main component of Panax ginseng C. A. Meyer. Ginsenoside Rg3 inhibits Na + and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S)-Ginsenoside Rg3 also inhibits Aβ levels, NF-κB activity, and COX-2 expression.
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5
(20R)-Ginsenoside Rg3
(20R)-Ginsenoside Rg3
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5 Cited Publications
Cat. No.: HY-N1376
CAS No.: 38243-03-7
Synonyms: (20R)-Propanaxadiol; R-ginsenoside Rg3
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Araliaceae Cancer

Target:  

Others

(20R)-ginsenoside Rg3 ((20R)-Propanaxadiol), one of the active compounds present in ginseng root, inhibits angiogenesis, and has anti-carcinogenic and antimetastatic effects .
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4
Ginsenoside Rg5
Ginsenoside Rg5
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4 Cited Publications
Cat. No.: HY-N0908
CAS No.: 186763-78-0
Category:  

Cardiovascular Disease Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Endocrinology Araliaceae

Target:  

IGF-1R NF-κB COX

Ginsenoside Rg5 is the main component of Red ginseng and IGF-1R agonist. Ginsenoside Rg5 compets for the binding site of IGF-1R and blocks the binding of IGF-1 to IGF-1R (IC50 about 90 nM). Ginsenoside Rg5 also inhibits the mRNA expression of COX-2 via suppression of the DNA binding activities of NF-κB p65.
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4
Ginsenoside Rg2
Ginsenoside Rg2
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4 Cited Publications
Cat. No.: HY-N0602
CAS No.: 52286-74-5
Synonyms: Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2
Category:  

Cardiovascular Disease Panax ginseng C. A. Meyer Triterpenes Neurological Disease Terpenoids Plants Disease Research Fields Araliaceae Cancer

Target:  

NF-κB Amyloid-β

Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg2 inhibits VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS). Ginsenoside Rg2 also reduces Aβ1-42 accumulation.
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3
Ginsenoside Rb2
Ginsenoside Rb2
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3 Cited Publications
Cat. No.: HY-N0040
CAS No.: 11021-13-9
Synonyms: Ginsenoside C
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Metabolic Disease Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

Influenza Virus Endogenous Metabolite Free Fatty Acid Receptor

Ginsenoside Rb2 is one of the main bioactive components of ginseng extracts. Rb2 can upregulate GPR120 gene expression. Ginsenoside Rb2 has antiviral effects.
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3
(20S)-Protopanaxadiol
(20S)-Protopanaxadiol
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3 Cited Publications
Cat. No.: HY-N0797
CAS No.: 30636-90-9
Synonyms: 20-Epiprotopanaxadiol; 20(S)-APPD
Category:  

Panax ginseng C. A. Meyer Triterpenes Human Gut Microbiota Metabolites Terpenoids Plants Endogenous metabolite Disease Research Fields Araliaceae Cancer

Target:  

P-glycoprotein Reactive Oxygen Species (ROS) Apoptosis

20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells .
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2
Eleutheroside E
Eleutheroside E
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2 Cited Publications
Cat. No.: HY-N0272
CAS No.: 39432-56-9
Category:  

Lignans Acanthopanax senticosus (Rupr. et Maxim.) Harms Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

Apoptosis NF-κB

Eleutheroside E is an important component of ginseng that can be taken orally. Eleutheroside E has anti-inflammatory and antioxidant properties, and it helps reduce apoptosis in heart cells caused by hypoxia-reoxygenation (H/R) damage. Eleutheroside E can improve type 2 diabetes, enhance cognitive function, and has neuroprotective effects .
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1
Ginsenoside Rb3
Ginsenoside Rb3
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1 Cited Publications
Cat. No.: HY-N0041
CAS No.: 68406-26-8
Synonyms: Gypenoside IV
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae Cancer

Target:  

NF-κB COX NO Synthase

Ginsenoside Rb3 is extracted from steamed Panax ginseng C. A. Meyer. Ginsenoside Rb3 exhibits inhibitory effect on TNFα-induced NF-κB transcriptional activity with an IC50 of 8.2 μM in 293T cell lines. Ginsenoside Rb3 also inhibits the induction of COX-2 and iNOS mRNA.
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1
Ginsenoside Rf
Ginsenoside Rf
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1 Cited Publications
Cat. No.: HY-N0601
CAS No.: 52286-58-5
Synonyms: Panaxoside Rf
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Endogenous metabolite Araliaceae

Target:  

Calcium Channel Endogenous Metabolite

Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca 2+ channel.
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1
Ginsenoside Rk3
Ginsenoside Rk3
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1 Cited Publications
Cat. No.: HY-N0906
CAS No.: 364779-15-7
Category:  

Cardiovascular Disease Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Araliaceae

Target:  

NF-κB

Ginsenoside Rk3 is present in the roots Panax ginseng herbs. Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells.
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1
Zingibroside R1
Zingibroside R1
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1 Cited Publications
Cat. No.: HY-N6924
CAS No.: 80930-74-1
Category:  

Infection Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Panax japonicas C. A. Mey. Metabolic Disease Plants Disease Research Fields Araliaceae Saccharides

Target:  

HIV PIN1 Fungal GLUT Reactive Oxygen Species (ROS)

Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .
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1
Ginsenoside Rh7
Ginsenoside Rh7
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1 Cited Publications
Cat. No.: HY-N4262
CAS No.: 343780-68-7
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Other Diseases Plants Disease Research Fields Araliaceae

Target:  

Others

Ginsenoside Rh7 is a minor saponin isolated from the leaves of Panax ginseng .
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1
Ginsenoside Rg1 (Standard)
Ginsenoside Rg1 (Standard)
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1 Cited Publications
Cat. No.: HY-N0045R
CAS No.: 22427-39-0
Synonyms: Panaxoside A (Standard); Panaxoside Rg1 (Standard)
Category:  

Panax ginseng C. A. Meyer Triterpenes Neurological Disease Anti-aging Terpenoids Plants Disease Research Fields Araliaceae Cancer

Target:  

Reference Standards Amyloid-β NF-κB Apoptosis

Ginsenoside Rg1 (Standard) is the analytical standard of Ginsenoside Rg1. This product is intended for research and analytical applications. Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.
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Ginsenoside Rc
Ginsenoside Rc
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Cat. No.: HY-N0042
CAS No.: 11021-14-0
Synonyms: Panaxoside Rc
Category:  

Panax ginseng C. A. Meyer Triterpenes Neurological Disease Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

GABA Receptor TNF Receptor Interleukin Related

Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA)-mediated ion channel currents (IGABA). Ginsenoside Rc inhibits the expression of TNF-α and IL-1β.
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Acetyl tetrapeptide-3
Acetyl tetrapeptide-3
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Cat. No.: HY-W129161
CAS No.: 827306-88-7
Target:  

Amino Acid Derivatives

Research Areas:  

Metabolic Disease

Acetyl tetrapeptide-3 is a synthetic peptide. Acetyl tetrapeptide-3 enhances the adhesion of hair follicles to the scalp but also promotes the development of new hair follicles. Acetyl tetrapeptide-3 stimulates the synthesis of collagen III in hair follicles. Acetyl tetrapeptide-3 combined with Biochanin A (HY-14595) and ginseng extracts, can stimulate dermal papilla extracellular matrix (ECM) proteins by increasing hydroxyproline, Collagen Type 3, and laminin, yielding a significant improvement in hair follicle size and hair anchoring .
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Ginsenoside F3
Ginsenoside F3
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Cat. No.: HY-N0600
CAS No.: 62025-50-7
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

Interleukin Related IFNAR NF-κB

Ginsenoside F3 is a saponin extracted from the leaves of Panax ginseng with immunoenhancing and antitumor immunostimulatory activities. Ginsenoside F3 upregulates RIPOR2 with a Kd value of 3.77 μM. Ginsenoside F3 enhances NF‑κB activation, upregulates T‑bet and downregulates GATA‑3, increases the production of IL‑2 and IFN‑γ, decreases the production of IL‑4 and IL‑10, reverses CD8⁺ T‑cell exhaustion, restores cytokine secretion, and enhances antitumor immunity in a mouse non‑small cell lung cancer model. Ginsenoside F3 can be used for the research of non-small cell lung cancer .
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(20R)-Ginsenoside Rh1
(20R)-Ginsenoside Rh1
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Cat. No.: HY-N1400
CAS No.: 80952-71-2
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Araliaceae Cancer

Target:  

PKC

(20R)-Ginsenoside Rh1 is the R-isomer of Ginsenoside Rh1 (HY-N0604), and it is found in red ginseng, ginseng, and other sources. (20R)-Ginsenoside Rh1 inhibits thrombin-induced conversion of fibrinogen to fibrin, exerting anticoagulant and antithrombotic effects .
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