1. Membrane Transporter/Ion Channel NF-κB Metabolic Enzyme/Protease Immunology/Inflammation Apoptosis
  2. P-glycoprotein Reactive Oxygen Species Apoptosis
  3. (20S)-Protopanaxadiol

(20S)-Protopanaxadiol  (Synonyms: 20-Epiprotopanaxadiol; 20(S)-APPD)

Cat. No.: HY-N0797 Purity: ≥98.0%
COA Handling Instructions

20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells.

For research use only. We do not sell to patients.

(20S)-Protopanaxadiol Chemical Structure

(20S)-Protopanaxadiol Chemical Structure

CAS No. : 30636-90-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 56 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 56 In-stock
5 mg USD 55 In-stock
10 mg USD 88 In-stock
50 mg USD 294 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells[1].

In Vitro

20S-protopanaxadiol treatment upregulates the flotillin-1 level in the rafts of N2a cells to 142.91±10.71% of the control. 20S-protopanaxadiol can have an opposite effect on raft resident protein flotillin-1, depending on the cell type[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight








Structure Classification
Initial Source

Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (217.05 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1705 mL 10.8523 mL 21.7047 mL
5 mM 0.4341 mL 2.1705 mL 4.3409 mL
10 mM 0.2170 mL 1.0852 mL 2.1705 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.43 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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