2. Membrane Transporter/Ion Channel NF-κB Metabolic Enzyme/Protease Immunology/Inflammation Apoptosis
  3. P-glycoprotein Reactive Oxygen Species Apoptosis
  4. (20S)-Protopanaxadiol

(20S)-Protopanaxadiol  (Synonyms: 20-Epiprotopanaxadiol; 20(S)-APPD)

Cat. No.: HY-N0797 Purity: ≥98.0%
COA Handling Instructions

20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells.

For research use only. We do not sell to patients.

(20S)-Protopanaxadiol Chemical Structure

(20S)-Protopanaxadiol Chemical Structure

CAS No. : 30636-90-9

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 56 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 56 In-stock
Solid
5 mg USD 55 In-stock
10 mg USD 88 In-stock
50 mg USD 294 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

(20S)-Protopanaxadiol Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells[1].

In Vitro

20S-protopanaxadiol treatment upregulates the flotillin-1 level in the rafts of N2a cells to 142.91±10.71% of the control. 20S-protopanaxadiol can have an opposite effect on raft resident protein flotillin-1, depending on the cell type[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(20S)-Protopanaxadiol Related Antibodies
Molecular Weight

460.73

Appearance

Solid

Formula

C30H52O3
CAS No.
SMILES

C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@]4([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC4)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (217.05 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1705 mL 10.8523 mL 21.7047 mL
5 mM 0.4341 mL 2.1705 mL 4.3409 mL
10 mM 0.2170 mL 1.0852 mL 2.1705 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.43 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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(20S)-Protopanaxadiol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(20S)-Protopanaxadiol30636-90-920-Epiprotopanaxadiol 20(S)-APPDP-glycoproteinReactive Oxygen SpeciesApoptosisP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243ginsengsaponinsAkt activityapoptosisvarious tumor cellsInhibitorinhibitorinhibit

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