1. Membrane Transporter/Ion Channel
    Metabolic Enzyme/Protease
    Immunology/Inflammation
    NF-κB
    Apoptosis
  2. P-glycoprotein
    Reactive Oxygen Species
    Apoptosis
  3. (20S)-Protopanaxadiol

(20S)-Protopanaxadiol (Synonyms: 20-Epiprotopanaxadiol; 20(S)-APPD)

Cat. No.: HY-N0797 Purity: ≥98.0%
Handling Instructions

20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells.

For research use only. We do not sell to patients.

(20S)-Protopanaxadiol Chemical Structure

(20S)-Protopanaxadiol Chemical Structure

CAS No. : 30636-90-9

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 97 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 97 In-stock
Estimated Time of Arrival: December 31
Solid
10 mg USD 88 In-stock
Estimated Time of Arrival: December 31
50 mg USD 294 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Description

20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells[1].

In Vitro

20S-protopanaxadiol treatment upregulates the flotillin-1 level in the rafts of N2a cells to 142.91±10.71% of the control. 20S-protopanaxadiol can have an opposite effect on raft resident protein flotillin-1, depending on the cell type[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

460.73

Formula

C30H52O3

CAS No.
SMILES
Structure Classification
Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (217.05 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1705 mL 10.8523 mL 21.7047 mL
5 mM 0.4341 mL 2.1705 mL 4.3409 mL
10 mM 0.2170 mL 1.0852 mL 2.1705 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.43 mM); Clear solution

*All of the co-solvents are available by MCE.
References
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Product Name:
(20S)-Protopanaxadiol
Cat. No.:
HY-N0797
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