2 Results for "

guinea pig lung tissue

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "guinea pig lung tissue" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-14648A
CAS No.: 1177-87-3
Purity:  99.84%
Synonyms: Dexamethasone 21-acetate; Hexadecadrol acetate
Research Areas:  

Inflammation/Immunology

Dexamethasone acetate (Dexamethasone 21-acetate) is the acetate form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone acetate has a longer duration of action than Dexamethasone. Dexamethasone acetate can accumulate at inflammatory sites, in mouse liver and mouse lung via nanostructured lipid carriers. Dexamethasone acetate can be used to prepare topical formulations for studies related to sensorineural hearing loss, γ-carrageenan-induced paw edema, chronic active hepatitis, pulmonary diseases, and inflammation after vitreoretinal surgery .
loading...
    loading...
Cat. No.: HY-136831
CAS No.: 105350-26-3
Synonyms: QMPB
Target:  

Leukotriene Receptor

Research Areas:  

Inflammation/Immunology

SR2640 is a highly efficient and selective LTD4/LTE4 antagonist that can specifically inhibit the smooth muscle contractions induced by LTD4 in the guinea pig ileum and trachea in a concentration-dependent manner, without affecting the contractions caused by histamine. SR2640 can concentration-dependently prevent the binding of 0.4 nM [3H] LTD4 to membrane receptors in guinea pig lung tissue, with an IC50 of 23 nM. SR2640 can shift the dose-response curve for bronchoconstriction induced by intravenous LTD4 in guinea pigs to the right, and the extent of this shift is positively correlated with the dose of SR2640 administered. SR2640 can be used in asthma research .
loading...
    loading...