7 Results for "

hemagglutinin stem

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "hemagglutinin stem" in MCE Product Catalog:

Cat. No.: HY-P99750
CAS No.: 1443004-16-7
Synonyms: CT-P23

Target:  

Influenza Virus

Research Areas:  

Infection

Navivumab (CT-P23) is a monoclonal antibody targeting the hemagglutinin (HA) of influenza A virus. Navivumab binds to the HA2 stem fusion domain and the low-variability HA2 region of influenza viruses. Navivumab neutralizes influenza A viruses of subtypes H1, H2, H5, and H9. Navivumab is applicable to research related to influenza and influenza A .
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Cat. No.: HY-P991446

Target:  

Influenza Virus

Research Areas:  

Infection

MEDI-8852 is a human IgG1 monoclonal antibody against influenza A virus hemagglutinin (HA). MEDI-8852 binds to the conserved HA stalk epitope and neutralizes viral infectivity. MEDI-8852 reduces viral titers in mouse lung tissues. MEDI-8852 is applicable to research related to pandemic influenza . Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991059
CAS No.: 2043950-09-8

Target:  

Influenza Virus

Research Areas:  

Infection

VIS-410 is an antibody inhibitor targeting the stem region of hemagglutinin (HA). VIS-410 inhibits influenza virus replication by blocking HA-mediated membrane fusion. VIS-410 exhibits broad-spectrum neutralization against influenza A viruses with group 1 and group 2 hemagglutinins, including subtypes such as H1N1, H3N2, H5N1, and H7N9 (H5N1 IC50 = 1.5 μg/mL). VIS-410 is applicable to research related to influenza A virus infection .
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Cat. No.: HY-D0871
CAS No.: 103-47-9
Synonyms: N-Cyclohexyltaurine
CHES (N-Cyclohexyltaurine) is a biological buffer reagent that binds to influenza virus hemagglutinin (HA). CHES mimics the binding mode of sialic acid to the HA receptor-binding site .
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Cat. No.: HY-P991054
CAS No.: 1422526-93-9

Research Areas:  

Infection

CR-8020 is a broadly neutralizing antibody targeting the stem region of influenza A virus hemagglutinin (HA), with IC50 values of 0.06 nM or 3.36 nM. CR-8020 mediates antibody-dependent cellular cytotoxicity by activating Fcγ receptors. CR-8020 blocks viral fusion and entry. CR-8020 protects mice from lethal influenza A virus challenge. CR-8020 can be used in research related to influenza A virus infections (H3N2 and H7N9) .
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Cat. No.: HY-P992083

Target:  

Influenza Virus

Research Areas:  

Infection

Anti-Influenza HA Antibody (CR9114) is an antibody against influenza virus hemagglutinin. Anti-Influenza HA Antibody (CR9114) binds to the conserved hemagglutinin (HA) stalk region of influenza A and B viruses, and mediates cross-subtype neutralization. Anti-Influenza HA Antibody (CR9114) is applicable for influenza-related research .
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Cat. No.: HY-P992482
VIR-2482 is a monoclonal antibody targeting influenza A hemagglutinin (HA). VIR-2482 is generated by introducing LS mutations (M428L/N434S) into the Fc region of MEDI8852 (HY-P991446). VIR-2482 binds to the conserved HA stem epitope across all 18 influenza A HA subtypes, neutralizes a broad spectrum of H1N1 and H3N2 strains, binds to FcγRIIIa, FcγRIIa and C1q, and induces antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. VIR-2482 reduces morbidity and mortality caused by seasonal influenza A strains and provides prophylactic protection in mice. VIR-2482 can be used in research related to influenza A disease .
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