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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
hormone-sensitive lipase
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "hormone-sensitive lipase" in MCE Product Catalog:
6
6 Publications Verification
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BAY 59-9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0.023 μM.
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3 Cited Publications
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HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability .
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1 Cited Publications
Synonyms: NNC0076-0079; 76-0079
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Hi 76-0079 (NNC0076-0079; 76-0079) is a lipase inhibitor that specifically targets hormone-sensitive lipase (HSL). Hi 76-0079 inhibits PNPB Hydrolysis in cell lysates of HEK293A cells
overexpressing Lipe with an IC50 value of 0.1 μM. Hi 76-0079 synergizes with the ATGL inhibitor Atglistatin (HY-15859) to block lipolysis in vitro. Hi 76-0079 can be used for the study of lipid metabolism .
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1 Cited Publications
Cat. No.: HY-164714
CAS No.: 308830-70-8
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HSL-IN-5 (Example 21) is a hormone sensitive lipase (HSL) inhibitor (IC50: 0.25 μM). HSL-IN-5 can be used for diabetes research .
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Carboxylesterase (CES) Free Fatty Acid Receptor Reactive Oxygen Species (ROS) Mitochondrial Metabolism Ferroptosis Apoptosis
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GR148672X is an inhibitor of carboxylesterase 1 (CES1) and hepatic microsomal triglyceride hydrolase (TGH). GR148672X blocks the catalytic activity of CES1, impairs the functions of triglyceride and cholesteryl ester lipase, reduces triglyceride mobilization and secretion, and decreases apolipoprotein B-100 secretion in primary rat hepatocytes. Under low-glucose conditions, GR148672X inhibits the survival of colorectal cancer cells by reducing free fatty acid availability, inducing toxic triglyceride accumulation, ROS production, mitochondrial damage, ferroptosis and apoptosis. GR148672X can be used in studies related to colorectal cancer and atherosclerosis .
Cat. No.: HY-P5081
CAS No.: 1678414-54-4
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Cat. No.: HY-P82854A
Synonyms: LIPE; hormone-sensitive lipase; HSL
Cat. No.: HY-P80464
Synonyms: hormone sensitive lipase antibody; hormone sensitive lipase testicular isoform antibody; hormone-sensitive lipase antibody; HSL antibody; LHS; lipase hormone sensitive antibody; LIPE antibody; LIPS_HUMAN antibody; Phospho-hormonesensitivelipase(S853); Phosphohormonesensitivelipase(S853)
Cat. No.: HY-P1210
CAS No.: 156159-18-1
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Cat. No.: HY-P1210A
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Cat. No.: HY-W714217
CAS No.: 105024-66-6
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Silafluofen is a hormone sensitive lipase (HSL) inhibitor. Silafluofen is an insecticide .
Cat. No.: HY-P5081A
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Cat. No.: HY-102056R
CAS No.: 654059-21-9
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BAY 59-9435 (Standard) is the analytical standard of BAY 59-9435 (HY-102056). This product is intended for research and analytical applications. BAY 59-9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0.023 μM.
Cat. No.: HY-101509R
CAS No.: 2095156-13-9
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HSL-IN-1 (Standard) is the analytical standard of HSL-IN-1 (HY-101509). This product is intended for research and analytical applications. HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability .
Cat. No.: HY-P11589
CAS No.: 2016043-80-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
