Search Result

Results for "

hormone-sensitive lipase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Hormone-Sensitive Lipase (HSL) (1) Lipase (7) Apoptosis (1) Carboxylesterase (CES) (1) Collagen (2) Ferroptosis (1) Free Fatty Acid Receptor (1) Insecticide (1) Keap1-Nrf2 (1) Melanocortin Receptor (2) Mitochondrial Metabolism (1) PPAR (1) Reactive Oxygen Species (ROS) (2) Reference Standards (2) TGF-β Receptor (2)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Endocrinology (2) Infection (1) Inflammation/Immunology (2) Metabolic Disease (7)

Inhibitors & Agonists

Peptides

Antibodies

Targets Recommended: Hormone-Sensitive Lipase (HSL) Lipase DAGL MAGL ATGL

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-102056

BAY 59-9435 4 Publications Verification	Lipase	Metabolic Disease
BAY 59-9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC₅₀ of 0.023 μM.

HY-153523

Hi 76-0079 1 Publications Verification NNC0076-0079; 76-0079	Lipase	Metabolic Disease
Hi 76-0079 (NNC0076-0079; 76-0079) is a lipase inhibitor that specifically targets hormone-sensitive lipase (HSL). Hi 76-0079 inhibits PNPB Hydrolysis in cell lysates of HEK293A cells overexpressing Lipe with an IC₅₀ value of 0.1 μM. Hi 76-0079 synergizes with the ATGL inhibitor Atglistatin (HY-15859) to block lipolysis in vitro. Hi 76-0079 can be used for the study of lipid metabolism .

HY-23524

HSL-IN-3 1 Publications Verification	Lipase	Others
HSL-IN-3, a boronic acid ester derivative, is an inhibitor of hormone-sensitive lipase (HSL) .

HY-110390

GR148672X	Carboxylesterase (CES) Free Fatty Acid Receptor Reactive Oxygen Species (ROS) Mitochondrial Metabolism Ferroptosis Apoptosis	Cardiovascular Disease Cancer
GR148672X is an inhibitor of carboxylesterase 1 (CES1) and hepatic microsomal triglyceride hydrolase (TGH). GR148672X blocks the catalytic activity of CES1, impairs the functions of triglyceride and cholesteryl ester lipase, reduces triglyceride mobilization and secretion, and decreases apolipoprotein B-100 secretion in primary rat hepatocytes. Under low-glucose conditions, GR148672X inhibits the survival of colorectal cancer cells by reducing free fatty acid availability, inducing toxic triglyceride accumulation, ROS production, mitochondrial damage, ferroptosis and apoptosis. GR148672X can be used in studies related to colorectal cancer and atherosclerosis .

HY-101509

HSL-IN-1 3 Publications Verification	Lipase	Metabolic Disease
HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC₅₀=2 nM) with a significantly reduced reactive metabolite liability .

HY-164714

HSL-IN-5	Lipase
HSL-IN-5 (Example 21) is a hormone sensitive lipase (HSL) inhibitor (IC₅₀: 0.25 μM). HSL-IN-5 can be used for diabetes research .

HY-P5081

Endotrophin (Mus musculus)	TGF-β Receptor Collagen	Inflammation/Immunology
Endotrophin (Mus musculus) is an adipokine, a cleavage fragment derived from Collagen VI, whose levels are elevated in adipose tissue and breast tumors of obese mice. Endotrophin (Mus musculus) activates the TGF-β signaling pathway and reduces the expression of hormone-sensitive lipase. Endotrophin (Mus musculus) induces adipogenesis, lipid accumulation, fibrosis, inflammation, angiogenesis, adipose tissue expansion, epithelial-mesenchymal transition, and insulin resistance; it also induces Cisplatin (HY-17394) resistance in cancer cells. Endotrophin (Mus musculus) can be used in research related to metabolic diseases such as obesity and type 2 diabetes, as well as cancers such as breast cancer .

HY-P1210

Lys-γ3-MSH(human)	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-P1210A

Lys-γ3-MSH(human) TFA	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) TFA potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) TFA is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) TFA can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-W714217

Silafluofen	Hormone-Sensitive Lipase (HSL) Insecticide	Infection Metabolic Disease
Silafluofen is a hormone sensitive lipase (HSL) inhibitor. Silafluofen is an insecticide .

HY-P5081A

Endotrophin (Mus musculus) TFA	TGF-β Receptor Collagen	Inflammation/Immunology
Endotrophin (Mus musculus) TFA is an adipokine, a cleavage fragment derived from Collagen VI, whose levels are elevated in adipose tissue and breast tumors of obese mice. Endotrophin (Mus musculus) TFA activates the TGF-β signaling pathway and reduces the expression of hormone-sensitive lipase. Endotrophin (Mus musculus) TFA induces adipogenesis, lipid accumulation, fibrosis, inflammation, angiogenesis, adipose tissue expansion, epithelial-mesenchymal transition, and insulin resistance; it also induces Cisplatin (HY-17394) resistance in cancer cells. Endotrophin (Mus musculus) TFA can be used in research related to metabolic diseases such as obesity and type 2 diabetes, as well as cancers such as breast cancer .

HY-102056R

BAY 59-9435 (Standard)	Lipase Reference Standards	Metabolic Disease
BAY 59-9435 (Standard) is the analytical standard of BAY 59-9435 (HY-102056). This product is intended for research and analytical applications. BAY 59-9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC₅₀ of 0.023 μM.

HY-101509R

HSL-IN-1 (Standard)	Lipase Reference Standards	Metabolic Disease
HSL-IN-1 (Standard) is the analytical standard of HSL-IN-1 (HY-101509). This product is intended for research and analytical applications. HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability .

HY-P11589

PIISVYWK	PPAR Reactive Oxygen Species (ROS) Keap1-Nrf2	Metabolic Disease
PIISVYWK is an orally active PPARγ Inhibitor, heme oxygenase-1 Activator, and Nrf2 Activator. PIISVYWK mediates activity via the HO-1/Nrf2 pathway, ameliorates oxidative stress, reduces inflammation, and mediates anti-obesity activity. PIISVYWK can be used for the research of obesity .

Cat. No.	Product Name	Target	Research Area

HY-P5081

Endotrophin (Mus musculus)	TGF-β Receptor Collagen	Inflammation/Immunology
Endotrophin (Mus musculus) is an adipokine, a cleavage fragment derived from Collagen VI, whose levels are elevated in adipose tissue and breast tumors of obese mice. Endotrophin (Mus musculus) activates the TGF-β signaling pathway and reduces the expression of hormone-sensitive lipase. Endotrophin (Mus musculus) induces adipogenesis, lipid accumulation, fibrosis, inflammation, angiogenesis, adipose tissue expansion, epithelial-mesenchymal transition, and insulin resistance; it also induces Cisplatin (HY-17394) resistance in cancer cells. Endotrophin (Mus musculus) can be used in research related to metabolic diseases such as obesity and type 2 diabetes, as well as cancers such as breast cancer .

HY-P1210

Lys-γ3-MSH(human)	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-P1210A

Lys-γ3-MSH(human) TFA	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) TFA potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) TFA is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) TFA can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-P5081A

Endotrophin (Mus musculus) TFA	TGF-β Receptor Collagen	Inflammation/Immunology
Endotrophin (Mus musculus) TFA is an adipokine, a cleavage fragment derived from Collagen VI, whose levels are elevated in adipose tissue and breast tumors of obese mice. Endotrophin (Mus musculus) TFA activates the TGF-β signaling pathway and reduces the expression of hormone-sensitive lipase. Endotrophin (Mus musculus) TFA induces adipogenesis, lipid accumulation, fibrosis, inflammation, angiogenesis, adipose tissue expansion, epithelial-mesenchymal transition, and insulin resistance; it also induces Cisplatin (HY-17394) resistance in cancer cells. Endotrophin (Mus musculus) TFA can be used in research related to metabolic diseases such as obesity and type 2 diabetes, as well as cancers such as breast cancer .

HY-P11589

PIISVYWK	PPAR Reactive Oxygen Species (ROS) Keap1-Nrf2	Metabolic Disease
PIISVYWK is an orally active PPARγ Inhibitor, heme oxygenase-1 Activator, and Nrf2 Activator. PIISVYWK mediates activity via the HO-1/Nrf2 pathway, ameliorates oxidative stress, reduces inflammation, and mediates anti-obesity activity. PIISVYWK can be used for the research of obesity .

Host:	Rabbit (4)
Reactivity:	Human (4) Rat (2) Mouse (2)
Application:	IHC-P (1) WB (4)
Isotype:	IgG (4)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Phosphorylated (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82854

	*Phospho-Hormone Sensitive* Lipase (Ser855) Antibody (YA2599)** LIPE; hormone-sensitive lipase; HSL	WB	Human
	Phospho-Hormone Sensitive Lipase (Ser855) Antibody (YA2599) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Hormone Sensitive Lipase (Ser855).

HY-P82854A

	*Phospho-Hormone Sensitive* Lipase (Ser855) Antibody (YA2599)(PBS only)** LIPE; hormone-sensitive lipase; HSL	WB	Human
	Phospho-Hormone Sensitive Lipase (Ser855) Antibody (YA2599) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Hormone Sensitive Lipase (Ser855).

HY-P810551

	*Phospho-Hormone sensitive* lipase (Ser660) Antibody (YA9820)** LIPE; hormone-sensitive lipase; HSL	WB	Human, Mouse, Rat
	Phospho-Hormone sensitive lipase (Ser660) Antibody (YA9820) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-Hormone sensitive lipase (Ser660).

HY-P80464

	*Phospho-Hormone sensitive* lipase (Ser853) Antibody (YA189)** hormone sensitive lipase antibody; hormone sensitive lipase testicular isoform antibody; hormone-sensitive lipase antibody; HSL antibody; LHS; lipase hormone sensitive antibody; LIPE antibody; LIPS_HUMAN antibody; Phospho-hormonesensitivelipase(S853); Phosphohormonesensitivelipase(S853)	WB, IHC-P	Human, Mouse, Rat
	Phospho-Hormone sensitive lipase (Ser853) Antibody (YA189) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Hormone sensitive lipase (Ser853).

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.