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  4. Hi 76-0079

Hi 76-0079  (Synonyms: NNC0076-0079; 76-0079)

Cat. No.: HY-153523 Purity: 99.90%
COA Handling Instructions

Molarity Calculator

Hi 76-0079 (Compound 31) is a hormone-sensitive lipase (HSL) inhibitor with an IC50 of 184 nM.

For research use only. We do not sell to patients.

Hi 76-0079 Chemical Structure

Hi 76-0079 Chemical Structure

CAS No. : 374567-94-9

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5 mg USD 180 In-stock
10 mg USD 290 In-stock
25 mg USD 530 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Hi 76-0079 Related Antibodies

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Description

Hi 76-0079 (Compound 31) is a hormone-sensitive lipase (HSL) inhibitor with an IC50 of 184 nM[1].

Molecular Weight

256.69

Formula

C11H13ClN2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NN1CCOCC1)OC2=CC=C(C=C2)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (973.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8957 mL 19.4787 mL 38.9575 mL
5 mM 0.7791 mL 3.8957 mL 7.7915 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.90%

COA (245 KB) HNMR (133 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8957 mL 19.4787 mL 38.9575 mL 97.3937 mL
5 mM 0.7791 mL 3.8957 mL 7.7915 mL 19.4787 mL
10 mM 0.3896 mL 1.9479 mL 3.8957 mL 9.7394 mL
15 mM 0.2597 mL 1.2986 mL 2.5972 mL 6.4929 mL
20 mM 0.1948 mL 0.9739 mL 1.9479 mL 4.8697 mL
25 mM 0.1558 mL 0.7791 mL 1.5583 mL 3.8957 mL
30 mM 0.1299 mL 0.6493 mL 1.2986 mL 3.2465 mL
40 mM 0.0974 mL 0.4870 mL 0.9739 mL 2.4348 mL
50 mM 0.0779 mL 0.3896 mL 0.7791 mL 1.9479 mL
60 mM 0.0649 mL 0.3246 mL 0.6493 mL 1.6232 mL
80 mM 0.0487 mL 0.2435 mL 0.4870 mL 1.2174 mL
100 mM 0.0390 mL 0.1948 mL 0.3896 mL 0.9739 mL
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Hi 76-0079 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hi 76-0079374567-94-9NNC0076-0079 76-0079OthersTG hydrolasehormone-sensitive lipaseInhibitorinhibitorinhibit

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