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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
human KMO
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "human KMO" in MCE Product Catalog:
Target:
Research Areas:
GSK 366 is a type II kynurenine-3-monooxygenase (KMO) inhibitor with IC50 values of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO). GSK 366 binds to KMO’s substrate site, prevents productive NADPH association, substrate binding, and FAD hydroperoxy species formation. GSK 366 does not stimulate hydrogen peroxide (H2O2) production and reduces H2O2 levels. GSK 366 can be used for the researches of inflammation and neurological disease, such as acute pancreatitis multiple organ dysfunction syndrome and Alzheimer’s disease .
Cat. No.: HY-RS07400
Target:
Research Areas:
KMO Human Pre-designed siRNA Set A contains three designed siRNAs for KMO gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704040
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KMO; Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase); Kynurenine 3-Monooxygenase; DJ317G22.1; Kynurenine 3-Hydroxylase
Species:
Human
Source:
E. coli
Cat. No.: HY-182692
CAS No.: 1953156-92-7
Target:
Research Areas:
KMO-IN-1 is a KMO inhibitor with a mean pIC50 of 8.5 against KMO. KMO-IN-1 can be used in the research of acute pancreatitis .
Cat. No.: HY-117086
CAS No.: 1953156-61-0
Target:
Research Areas:
GSK065 is a KMO inhibitor with an IC50 of 2.5 nM and a Ki of 0.05 nM. GSK065 prevents the effective binding of NADPH to its substrate. GSK065 can be used in studies related to multiple organ dysfunction syndrome associated with acute pancreatitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
