1953156-61-0
1953156-61-0
Chemical Structure
GSK065
- CAS No.: 1953156-61-0
- Formula:C17H15ClN2O4
- Molecular Weight:346.77
IUPAC Name: (R)-3-(5-chloro-6-(1-(pyridin-2-yl)ethoxy)benzo[d]isoxazol-3-yl)propanoic acid
InChIKey: WPAHVUADNLXSOM-SNVBAGLBSA-N
SMILES: C(CC(O)=O)C=1C=2C(=CC(O[C@H](C)C3=CC=CC=N3)=C(Cl)C2)ON1
Biological Activity: GSK065 is a KMO inhibitor with an IC50 of 2.5 nM and a Ki of 0.05 nM. GSK065 prevents the effective binding of NADPH to its substrate. GSK065 can be used in studies related to multiple organ dysfunction syndrome associated with acute pancreatitis[1].
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GSK065 | GSK065 is a KMO inhibitor with an IC50 of 2.5 nM and a Ki of 0.05 nM. GSK065 prevents the effective binding of NADPH to its substrate. GSK065 can be used in studies related to multiple organ dysfunction syndrome associated with acute pancreatitis. | |||||||||||||||||||||
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