1 Result for "

human-CCR8 knock-in mouse models

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "human-CCR8 knock-in mouse models" in MCE Product Catalog:

Cat. No.: HY-P991481

Target:  

CCR

Research Areas:  

Inflammation/Immunology Cancer

S-531011 is a high-affinity, selective, and reversible CCR8 ligand with antibody-dependent cellular cytotoxicity (ADCC) against CCR8-expressing cells. S-531011 induces the death of tumor-infiltrating CCR8 + regulatory T cells while preserving regulatory T cells in peripheral blood, thereby reinvigorating anti-tumor immunity. The combination of S-531011 with anti-PD-1 antibody effectively inhibits tumor growth, and S-531011 can be used for research on advanced solid tumors and various cancers including non-small cell lung cancer, ovarian cancer, colon cancer, breast cancer, and pancreatic ductal adenocarcinoma .
loading...
    loading...