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Results for "

immunodominant

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Arenavirus (2) Bacterial (2) EBV (1) HSV (4) IFNAR (1) Influenza Virus (1) MHC (6) SARS-CoV (2) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (9) Inflammation/Immunology (12) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3333

KSPWFTTL	MHC	Inflammation/Immunology Cancer
KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes .

HY-P4193

AH1	MHC	Inflammation/Immunology Cancer
AH1 is an immunodominant MHC class I-restricted nonamer peptide recognized by CD8 ⁺ cytotoxic T lymphocytes. AH1 derives from the envelope protein (gp70) of an endogenous ecotropic murine leukemia virus and is presented by the MHC class I L ^d molecule. AH1 can be used for the research of colorectal carcinoma .

HY-P1571

Nucleoprotein (396-404) NP 396	Arenavirus	Inflammation/Immunology
Nucleoprotein (396-404) is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .

HY-P1837

Influenza HA (518-526)	Influenza Virus HSV	Infection
Influenza HA (518-526) is an H-2d-restricted CTL epitope derived from influenza virus hemagglutinin. Influenza HA (518-526) is highly conserved across various H5N1, some H9N2, and H1N1 strains. Influenza HA (518-526) binds to the mouse MHC class I allele K ^d to form a complex, which is then recognized by specific CD8 ⁺ T cells. Influenza HA (518-526) is an immunodominant epitope in influenza-infected BALB/c mice, and it stimulates CD8 ⁺ T cells to secrete IFN-γ to induce a robust immune response. Currently, Influenza HA (518-526) is widely used in research related to respiratory syncytial virus (RSV), influenza virus, and H5N1 influenza .

HY-P3723

MBP (83-99)	IFNAR	Inflammation/Immunology
MBP (83-99) is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells .

HY-P3333A

KSPWFTTL TFA	MHC	Inflammation/Immunology Cancer
KSPWFTTL TFA is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL TFA can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes .

HY-P4743

FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578)	HSV	Infection
FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578) is a FITC labeled HHV-2 Envelope Glycoprotein G (561-578). HHV-2 Envelope Glycoprotein G (561-578) is an immunodominant region of glycoprotein G (gG-2) reactive with all herpes simplex (HSV-2) sera .

HY-P10497

EBV BZLF1 (190-197)	Bacterial	Infection Inflammation/Immunology
EBV BZLF1 (190-197) is an immunodominant CEF-controlling peptide derived from Epstein-Barr virus (EBV). EBV BZLF1 (190-197) is a suitable epitope for CD8+ T cells to stimulate the release of IFNg. CTL responses to EBV BZLF1 (190-197) are diverse and cross-recognize similar peptides from both host self-proteins and bacterial proteins. EBV BZLF1 (190-197) can be used to study autoimmune diseases .

HY-P10497A

EBV BZLF1 (190-197) TFA	Bacterial	Infection Inflammation/Immunology
EBV BZLF1 (190-197) TFA is an immunodominant CEF-controlling peptide derived from Epstein-Barr virus (EBV). EBV BZLF1 (190-197) TFA is a suitable epitope for CD8+ T cells to stimulate the release of IFNg. CTL responses to EBV BZLF1 (190-197) TFA are diverse and cross-recognize similar peptides from both host self-proteins and bacterial proteins. EBV BZLF1 (190-197) TFA can be used to study autoimmune diseases .

HY-P10689

NQK-A8 peptide	SARS-CoV	Infection
NQK-A8 peptide is an immunodominant peptide of seasonal coronaviruses HKU1-CoV and OC43-CoV .

HY-P10382

M133 peptide	MHC	Inflammation/Immunology
M133 peptide is a coronavirus-specific CD4 T cell epitope. M133 peptide is immunodominant in mice infected with the neurotropic coronavirus (the JHM strain of mouse hepatitis virus). M133 peptide forms a complex with MHC II molecules, which is recognized by specific TCRs, thereby activating CD4 T cells .

HY-P10688

NQK-Q8 peptide	SARS-CoV	Infection
NQK-Q8 peptide is an immunodominant peptide of SARS-Cov-2 .

HY-P4318

HHV-2 Envelope Glycoprotein G (552-574)	HSV	Infection
HHV-2 Envelope Glycoprotein G (552-574) is an immunodominant region of glycoprotein G (gG-2) reactive with all herpes simplex (HSV-2) sera .

HY-P1571A

Nucleoprotein (396-404) TFA NP 396 TFA	Arenavirus	Inflammation/Immunology
Nucleoprotein (396-404) TFA is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) TFA is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .

HY-P1862

HSV-gB2 (498-505)	HSV	Infection
HSV-gB2 (498-505) is an immunodominant epitope from herpes simplex virus (HSV) glycoprotein B residues 498-505, acts as H-2Kb-restricted and HSV-1/2-cross-reactive cytotoxic T-lymphocyte (CTL) recognition epitope .

HY-P11127

MBP (111-129)	Transmembrane Glycoprotein MHC	Inflammation/Immunology
MBP (111-129) is a polypeptide that constitutes an immunodominant epitope cluster restricted by HLA-DRB10401. MBP (111-129) is an antagonist for the clone HD4-1C2 TCR* and an agonist for clone MS2-3C8 TCR. MBP (111-129) can be used for on multiple sclerosis and T cell biology .

HY-P11713

EBNA3B 399-408	EBV MHC	Infection Cancer
EBNA3B 399-408 is an immunodominant HLA-A11-restricted cytotoxic T-lymphocyte epitope in EBNA3B. EBNA3B 399-408 can be used in the research of EBV infection, empyema-associated lymphoma, and nasal natural killer cell lymphoma .

Cat. No.	Product Name	Target	Research Area

HY-P3333

KSPWFTTL	MHC	Inflammation/Immunology Cancer
KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes .

HY-P4193

AH1	MHC	Inflammation/Immunology Cancer
AH1 is an immunodominant MHC class I-restricted nonamer peptide recognized by CD8 ⁺ cytotoxic T lymphocytes. AH1 derives from the envelope protein (gp70) of an endogenous ecotropic murine leukemia virus and is presented by the MHC class I L ^d molecule. AH1 can be used for the research of colorectal carcinoma .

HY-P10554

Myhc-α(334–352)	Peptides	Cardiovascular Disease Others Inflammation/Immunology
Myhc-α(334–352) is a sequence fragment of amino acid residues 334 to 352 of cardiac myosin heavy chain α. Myhc-α(334–352) is an immunodominant epitope that can induce autoimmune reactions in A/J mice, leading to the occurrence of myocarditis. Myhc-α(334–352) can be used to study the autoimmune pathways of myocarditis and dilated cardiomyopathy .

HY-P1571

Nucleoprotein (396-404) NP 396	Arenavirus	Inflammation/Immunology
Nucleoprotein (396-404) is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .

HY-P1837

Influenza HA (518-526)	Influenza Virus HSV	Infection
Influenza HA (518-526) is an H-2d-restricted CTL epitope derived from influenza virus hemagglutinin. Influenza HA (518-526) is highly conserved across various H5N1, some H9N2, and H1N1 strains. Influenza HA (518-526) binds to the mouse MHC class I allele K ^d to form a complex, which is then recognized by specific CD8 ⁺ T cells. Influenza HA (518-526) is an immunodominant epitope in influenza-infected BALB/c mice, and it stimulates CD8 ⁺ T cells to secrete IFN-γ to induce a robust immune response. Currently, Influenza HA (518-526) is widely used in research related to respiratory syncytial virus (RSV), influenza virus, and H5N1 influenza .

HY-P3723

MBP (83-99)	IFNAR	Inflammation/Immunology
MBP (83-99) is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells .

HY-P5451

PLP (178-191)	Peptides	Others
PLP (178-191) is a biological active peptide. (This is amino acids 178 to 191 fragment of the proteolipid protein (PLP), an immunodominant encephalitogenic epitope in SJL mice, one of two major encephalitogenic epitopes. PLP peptide 178 to 191 was compared with another encephalitogenic peptide, 139 to 151. The day of onset of disease induced by PLP 178 to 191 was earlier, but the incidence, severity, and histologic features were indistinguishable.)

HY-P3333A

KSPWFTTL TFA	MHC	Inflammation/Immunology Cancer
KSPWFTTL TFA is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL TFA can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes .

HY-P1996

Tiplimotide NBI-5788	Peptides	Neurological Disease Inflammation/Immunology
Tiplimotide (NBI-5788) is an altered peptide ligand (APL) designed from an immunodominant region (83-99) of the neuroantigen myelin basic protein (MBP). Tiplimotide can selectively reduce the production of inflammatory cytokines by pathogenic T-cells. Tiplimotide can be used for the research of multiple sclerosis (MS) .

HY-P4743

FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578)	HSV	Infection
FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578) is a FITC labeled HHV-2 Envelope Glycoprotein G (561-578). HHV-2 Envelope Glycoprotein G (561-578) is an immunodominant region of glycoprotein G (gG-2) reactive with all herpes simplex (HSV-2) sera .

HY-P10497

EBV BZLF1 (190-197)	Bacterial	Infection Inflammation/Immunology
EBV BZLF1 (190-197) is an immunodominant CEF-controlling peptide derived from Epstein-Barr virus (EBV). EBV BZLF1 (190-197) is a suitable epitope for CD8+ T cells to stimulate the release of IFNg. CTL responses to EBV BZLF1 (190-197) are diverse and cross-recognize similar peptides from both host self-proteins and bacterial proteins. EBV BZLF1 (190-197) can be used to study autoimmune diseases .

HY-P10497A

EBV BZLF1 (190-197) TFA	Bacterial	Infection Inflammation/Immunology
EBV BZLF1 (190-197) TFA is an immunodominant CEF-controlling peptide derived from Epstein-Barr virus (EBV). EBV BZLF1 (190-197) TFA is a suitable epitope for CD8+ T cells to stimulate the release of IFNg. CTL responses to EBV BZLF1 (190-197) TFA are diverse and cross-recognize similar peptides from both host self-proteins and bacterial proteins. EBV BZLF1 (190-197) TFA can be used to study autoimmune diseases .

HY-P10689

NQK-A8 peptide	SARS-CoV	Infection
NQK-A8 peptide is an immunodominant peptide of seasonal coronaviruses HKU1-CoV and OC43-CoV .

HY-P10382

M133 peptide	MHC	Inflammation/Immunology
M133 peptide is a coronavirus-specific CD4 T cell epitope. M133 peptide is immunodominant in mice infected with the neurotropic coronavirus (the JHM strain of mouse hepatitis virus). M133 peptide forms a complex with MHC II molecules, which is recognized by specific TCRs, thereby activating CD4 T cells .

HY-P10688

NQK-Q8 peptide	SARS-CoV	Infection
NQK-Q8 peptide is an immunodominant peptide of SARS-Cov-2 .

HY-P4318

HHV-2 Envelope Glycoprotein G (552-574)	HSV	Infection
HHV-2 Envelope Glycoprotein G (552-574) is an immunodominant region of glycoprotein G (gG-2) reactive with all herpes simplex (HSV-2) sera .

HY-P1571A

Nucleoprotein (396-404) TFA NP 396 TFA	Arenavirus	Inflammation/Immunology
Nucleoprotein (396-404) TFA is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) TFA is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen .

HY-P1862

HSV-gB2 (498-505)	HSV	Infection
HSV-gB2 (498-505) is an immunodominant epitope from herpes simplex virus (HSV) glycoprotein B residues 498-505, acts as H-2Kb-restricted and HSV-1/2-cross-reactive cytotoxic T-lymphocyte (CTL) recognition epitope .

HY-P5496

AAV2 Epitope	Peptides	Others
AAV2 Epitope is a biological active peptide. (This peptide is the capsid derived immunodominant adeno-associated virus 2 (AAV2), CD8 T cell epitope. Liver toxicity observed in a clinical trial of AAV2 delivered systemically to patients with hemophilia was ascribed to killing of vector-transduced hepatocytes by capsid-specific T-cells.)

HY-P10522

MBP Ac1-9	Peptides	Others
MBP Ac1-9 refers to a peptide fragment of myelin basic protein (MBP). MBP Ac1-9 is an immunodominant epitope in the experimental autoimmune encephalomyelitis (EAE) model, which can induce T cell immune response and lead to pathological changes similar to multiple sclerosis. MBP Ac1-9 can be used to study T cell activation and autoimmune response .

HY-P11127

MBP (111-129)	Transmembrane Glycoprotein MHC	Inflammation/Immunology
MBP (111-129) is a polypeptide that constitutes an immunodominant epitope cluster restricted by HLA-DRB10401. MBP (111-129) is an antagonist for the clone HD4-1C2 TCR* and an agonist for clone MS2-3C8 TCR. MBP (111-129) can be used for on multiple sclerosis and T cell biology .

HY-P11713

EBNA3B 399-408	EBV MHC	Infection Cancer
EBNA3B 399-408 is an immunodominant HLA-A11-restricted cytotoxic T-lymphocyte epitope in EBNA3B. EBNA3B 399-408 can be used in the research of EBV infection, empyema-associated lymphoma, and nasal natural killer cell lymphoma .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P74898

	NS3 protease Protein, HCV (GST) Hepatitis C virus (HCV-1a) NS3 protease / helicase immunodominant region Protein ( GST)	Virus	E. coli
	NS3 protease Protein is a zinc-dependent serine protease.NS3 needs to bind to the viral protein NS4A to enable additional conformation changes that enhance activity and appropriate intracellular localization.NS3 protein induces Caspase-8-mediated apoptosis independently of its protease or helicase activity.NS3 protease Protein, HCV (GST) is the recombinant Virus-derived NS3 protease protein, expressed by E.coli , with N-GST labeled tag.

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