178823-45-5
Chemical Structure
MBP (83-99)
- CAS No.: 178823-45-5
- Formula:C93H143N25O24
- Molecular Weight:1995.28
SMILES: OC(CC[C@H](N)C(N[C@@H](CC(N)=O)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N4[C@@H](CCC4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O
Biological Activity: MBP (83-99) is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells[1][2].
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MBP (83-99) | MBP (83-99) is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells. | |||||||||||||||||||||
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- [1]. Hemmer B, et al. Human T-cell response to myelin basic protein peptide (83-99): extensive heterogeneity in antigen recognition, function, and phenotype. Neurology. [Content Brief]
- [2]. Katsara M, et al. A double mutation of MBP(83-99) peptide induces IL-4 responses and antagonizes IFN-gamma responses. J Neuroimmunol. 2008 Aug 30;200(1-2):77-89. [Content Brief]
Keywords
