8 Results for "

insulin secretory

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "insulin secretory" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B0481
CAS No.: 72432-03-2
Synonyms: BAY1099; BAY-m1099
Miglitol (BAY-m1099) is an orally active antidiabetic compound that inhibits the breakdown of glycoconjugates into glucose. Miglitol inhibits glycoside hydrolase enzymes called α-glucosidases. Miglitol inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase. Dietary supplementation with Miglitol from pre-onset stage in OLETF rats delays the onset and development of diabetes and preserves the insulin secretory function of pancreatic islets .
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Cat. No.: HY-P990990
CAS No.: 2803875-75-2
Synonyms: YN011; YN012; YN015

Target:  

GLP Receptor

Efsubaglutide alfa is a long-acting humanised GLP-1 receptor agonist . Efsubaglutide alfa binds specifically to the GLP-1 receptor, enhancing glucose-dependent insulin secretion, suppressing glucagon release, and promoting β-cell proliferation and increased β-cell mass. Efsubaglutide alfa improves glucose tolerance, increases pancreatic insulin content, and enhances β-cell secretory responses in isolated human islets. Efsubaglutide alfa reduces liver steatosis, lowers NAFLD Activity Scores, improves perisinusoidal collagen features, reduces serum ALT and AST levels, improves fasting glucose and triglyceride levels, and reduces body weight, liver weight and liver-to-body weight ratio. Efsubaglutide alfa can be used for the research of type 2 diabetes. Efsubaglutide alfa can be used for the research of metabolic dysfunction-associated steatohepatitis .
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Cat. No.: HY-P1871A
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Amylin (IAPP), feline TFA is a 37-amino acid polypeptide from feline. Amylin (IAPP), feline TFA is one of the major secretory products of β-cells of the pancreatic islets. Amylin (IAPP), feline TFA is a regulatory peptide, which inhibits insulin and glucagon secretion .
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Cat. No.: HY-P1871
CAS No.: 213779-12-5
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Amylin (IAPP), feline is a 37-amino acid polypeptide from feline. Amylin (IAPP), feline is one of the major secretory products of β-cells of the pancreatic islets. Amylin (IAPP), feline is a regulatory peptide, which inhibits insulin and glucagon secretion .
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Cat. No.: HY-123421
CAS No.: 47453-14-5
Target:  

Histamine Receptor

Research Areas:  

Metabolic Disease

UK-9040, a derivative of the antihistamine Triprolidine (HY-B1808), is an orally active inhibitor of gastric secretory. UK-9040 reduces gastric acid, pepsin, and volume output in response to food, Insulin (HY-P0035), Histamine (HY-B1204), N-methyl histamine, and Pentagastrin (HY-A0261) .
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Cat. No.: HY-183955
CAS No.: 2041071-54-7
Target:  

DYRK GSK-3

GNF7156 is a DYRK1A/GSK3B inhibitor, IC50 values of 100 nM for DYRK1A and 40 nM for GSK3B. GNF7156 inhibits DYRK1A and GSK3B kinase activity and induces NFAT nuclear retention. GNF7156 stimulates beta-cell cycle entry and division and maintains insulin secretory capacity. GNF7156 can be used for the research of type 1 diabetes, and type 2 diabetes .
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Cat. No.: HY-P7736
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CPE; insulin Granule-Associated Carboxypeptidase; Carboxypeptidase E; CPH; Enkephalin Convertase; Epididymis secretory Sperm Binding Protein; Carboxypeptidase H; Carbocypeptidase E; Prohormone-Processing Carboxypeptidase; IDDHH; Cobalt-Stimulated Chromaffin Granule Carboxypeptidase; BDVS
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705523
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CPE; insulin Granule-Associated Carboxypeptidase; Carboxypeptidase E; CPH; Enkephalin Convertase; Epididymis secretory Sperm Binding Protein; Carboxypeptidase H; Carbocypeptidase E; Prohormone-Processing Carboxypeptidase; IDDHH; Cobalt-Stimulated Chromaff
Species:  
Human
Source:  
HEK293
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