Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
217 Results for "
insulin-like
" in MedChemExpress (MCE) Product Catalog:
Products (217)
217 Results for "insulin-like" in MCE Product Catalog:
31
31 Publications Verification
Synonyms: AXL1717; Picropodophyllotoxin; PPP
27
27 Cited Publications
Cat. No.: HY-P7018
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-like Growth Factor 1; insulin-like Growth Factor IB; insulin-like Growth Factor I; insulin-like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-like
13
Target:
Research Areas:
NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 has antitumor activity .
12
12 Cited Publications
Cat. No.: HY-P7070
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-like Growth Factor 1; insulin-like Growth Factor IB; insulin-like Growth Factor I; insulin-like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-like
11
11 Cited Publications
Synonyms: RC-1291; ONO-7643
Target:
Research Areas:
Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia .
11
11 Cited Publications
Synonyms: RC-1291 hydrochloride; ONO-7643 hydrochloride
Target:
Research Areas:
Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia .
9
9 Cited Publications
Cat. No.: HY-P2093
CAS No.: 1083433-49-1
Target:
Research Areas:
9
9 Cited Publications
Cat. No.: HY-P2093B
Target:
Research Areas:
7
7 Cited Publications
Target:
Research Areas:
GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity .
6
6 Cited Publications
Cat. No.: HY-P70788
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-like Growth Factor 1; insulin-like Growth Factor IB; insulin-like Growth Factor I; insulin-like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-like
5
5 Cited Publications
Target:
Research Areas:
BMS-536924 is an orally active, competitive and selective insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IR) inhibitor with IC50s of 100 nM and 73 nM, respectively. BMS-536924 has anti-cancer activity .
5
5 Cited Publications
Synonyms: MK-677 free base; MK-0677 free base
Target:
Research Areas:
Ibutamoren (MK-677 free base; MK-0677 free base) is an orally active non-peptide growth hormone secretagogue receptor agonist. Ibutamoren activates signal cascades by mimicking endogenous ligands, triggers pulsatile release of growth hormone from the pituitary gland, and increases serum levels of IGF-1 and insulin-like growth factor-binding protein 3. Ibutamoren not only increases the frequency of growth hormone pulses in male individuals, but also promotes elevated bone formation markers in female individuals with postmenopausal osteoporosis. The combination of Ibutamoren with Alendronate sodium hydrate (HY-11101) significantly increases bone mineral density at the femoral neck. However, Ibutamoren may cause mild, reversible adverse reactions such as increased appetite, fluid retention, and elevated fasting blood glucose. Ibutamoren has been widely used in studies related to idiopathic growth hormone deficiency, sarcopenia, Alzheimer's disease, and osteoporosis .
4
4 Cited Publications
Cat. No.: HY-P70698
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-like Growth Factor 1; insulin-like Growth Factor IB; insulin-like Growth Factor I; insulin-like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-like
3
3 Cited Publications
Cat. No.: HY-P7203
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-like Growth Factor 1; insulin-like Growth Factor IB; insulin-like Growth Factor I; insulin-like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-like
3
3 Cited Publications
Cat. No.: HY-P7019
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF2; insulin-like Growth Factor 2 (Somatomedin A); Prev. C11orf43; insulin-like Growth Factor Type 2; insulin-like Growth Factor 2; Somatomedin A; IGF-II; Somatomedin-A; insulin-like Growth Factor II; PP9974; T3M-11-Derived Growth Factor; IGF-2; FLJ44734
3
3 Cited Publications
Cat. No.: HY-110135A
Purity: 99.42%
Target:
Research Areas:
NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex (Kis=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects .
2
2 Cited Publications
Cat. No.: HY-B0025
CAS No.: 83480-29-9
Target:
2
2 Cited Publications
Cat. No.: HY-P70783
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-like Growth Factor 1; insulin-like Growth Factor IB; insulin-like Growth Factor I; insulin-like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-like
2
2 Cited Publications
Cat. No.: HY-P7368
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGFBP2; insulin-like Growth Factor Binding Protein 2 (36kD); Prev. IBP2; IGF-BP53; insulin-like Growth Factor-Binding Protein 2; IGFBP-2; insulin-like Growth Factor Binding Protein 2, 36kDa; IBP-2; IGF-Binding Protein 2; BP2; insulin like Growth Factor Bi
2
2 Cited Publications
Cat. No.: HY-P7021
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGFBP5; IBP-5; insulin like Growth Factor Binding Protein 5; IBP5; insulin-like Growth Factor-Binding Protein 5; insulin-like Growth Factor Binding Protein 5; IGF-Binding Protein 5; IGFBP5 Protein; IGFBP-5
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
