Search Result

Results for "

insulin-like

" in MedChemExpress (MCE) Product Catalog:

By Targets:	IGF-1R (32) Adenylate Cyclase (2) Akt (2) Antibiotic (2) Apoptosis (12) Autophagy (3) Bacterial (1) CDK (2) Cytochrome P450 (1) DNA/RNA Synthesis (2) Drug Derivative (1) Drug Metabolite (1) EGFR (1) Endogenous Metabolite (1) Fungal (2) G Protein-coupled Receptor Kinase (GRK) (1) GHR (3) GHSR (6) Glycosidase (3) iGluR (1) Insulin Receptor (15) Interleukin Related (1) Isotope-Labeled Compounds (4) mRNA (9) mTOR (1) NO Synthase (1) Phospholipase (1) PI3K (1) Reference Standards (6) ROCK (1) RXFP Receptor (3) Small Interfering RNA (siRNA) (2) Somatostatin Receptor (2) TNF Receptor (1) VEGFR (1)
By Research Areas:	Cancer (34) Cardiovascular Disease (4) Endocrinology (15) Infection (2) Inflammation/Immunology (8) Metabolic Disease (27) Neurological Disease (3)
Oligonucleotides:	mRNA (9) Antisense Oligonucleotides (4)

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: IGF-1R

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15494

Picropodophyllin 25+ Cited Publications AXL1717; Picropodophyllotoxin; PPP	IGF-1R Apoptosis	Endocrinology Cancer
Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC₅₀ of 1 nM.

HY-14734

Anamorelin 5+ Cited Publications RC-1291; ONO-7643	GHSR	Endocrinology Cancer
Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia .

HY-10262

BMS-536924 5+ Cited Publications	IGF-1R Insulin Receptor Apoptosis	Endocrinology Cancer
BMS-536924 is an orally active, competitive and selective insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IR) inhibitor with IC₅₀s of 100 nM and 73 nM, respectively. BMS-536924 has anti-cancer activity .

HY-144873

AVJ16	Insulin Receptor Apoptosis	Cancer
AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein IGF2BP1 with a good affinity of K_d of 1.4μM. AVJ16 interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation .

HY-50866

NVP-AEW541 10+ Cited Publications AEW541	IGF-1R Insulin Receptor Autophagy	Endocrinology Cancer
NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC₅₀ value of 0.15 μM. NVP-AEW541 also inhibits InsR, IC₅₀ with a value of 0.14 μM. NVP-AEW541 has antitumor activity .

HY-P99294

Ganitumab 1 Publications Verification AMG 479; Human Anti-IGF1R Recombinant Antibody	IGF-1R	Cancer
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the *human type 1 insulin-like* growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D**=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-W010128

6-(Dimethylamino)purine 6-Dimethylaminopurine; 6-DMAP	CDK DNA/RNA Synthesis Apoptosis	Cancer
6-(Dimethylamino) purine (6-Dimethylaminopurine) is a serine threonine protein kinase inhibitor. 6-(Dimethylamino) purine can inhibit prolactin induced expression of lactoprotein genes in rabbit mammary gland cells. 6-(Dimethylamino) purine can affect the maturation of mammalian oocytes. 6-(Dimethylamino) purine can lead to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induce apoptosis in lymphoma cells (apoptosis) .

HY-B0025

Voglibose 1 Publications Verification	Glycosidase	Metabolic Disease
Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis .

HY-P2093

S961 5+ Cited Publications	Insulin Receptor	Metabolic Disease
S961 is an high-affinity and selective insulin receptor (IR) antagonist with IC₅₀s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively .

HY-14734A

Anamorelin hydrochloride 5+ Cited Publications RC-1291 hydrochloride; ONO-7643 hydrochloride	GHSR	Endocrinology Cancer
Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC₅₀ of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia .

HY-10524

GSK1904529A 5+ Cited Publications	IGF-1R Insulin Receptor Apoptosis	Endocrinology Cancer
GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC₅₀s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC₅₀>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity .

HY-P99197

Figitumumab CP-751871	IGF-1R	Cancer
Figitumumab (CP-751871) is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC₅₀ of 1.8 nM .

HY-P2093B

S961 acetate 5+ Cited Publications	Insulin Receptor	Metabolic Disease
S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC₅₀s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively .

HY-108905

Mecasermin Human IGF-I; FK 780	IGF-1R	Metabolic Disease
Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .

HY-10199A

Ibutamoren 5 Publications Verification MK-677 free base; MK-0677 free base	GHSR Insulin Receptor	Neurological Disease Metabolic Disease
Ibutamoren (MK-677 free base; MK-0677 free base) is an orally active non-peptide growth hormone secretagogue receptor agonist. Ibutamoren activates signal cascades by mimicking endogenous ligands, triggers pulsatile release of growth hormone from the pituitary gland, and increases serum levels of IGF-1 and insulin-like growth factor-binding protein 3. Ibutamoren not only increases the frequency of growth hormone pulses in male individuals, but also promotes elevated bone formation markers in female individuals with postmenopausal osteoporosis. The combination of Ibutamoren with Alendronate sodium hydrate (HY-11101) significantly increases bone mineral density at the femoral neck. However, Ibutamoren may cause mild, reversible adverse reactions such as increased appetite, fluid retention, and elevated fasting blood glucose. Ibutamoren has been widely used in studies related to idiopathic growth hormone deficiency, sarcopenia, Alzheimer's disease, and osteoporosis .

HY-112606

ML-290	RXFP Receptor	Others
ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC₅₀ of 94 nM . ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.

HY-P1777

IGF-I (24-41) insulin-like Growth Factor I (24-41)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .

HY-18785

Indirubin Derivative E804	IGF-1R	Endocrinology Cancer
Indirubin Derivative E804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC₅₀ of 0.65 μM for IGF1R.

HY-117483

Gly-Pro-Glu	iGluR	Neurological Disease
Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC₅₀ value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection .

HY-145110

IGF-1R inhibitor-2	IGF-1R	Cancer
IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis .

HY-110135A

NBI-31772 hydrate 3 Publications Verification	IGF-1R	Neurological Disease
NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex (K_is=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects .

HY-15494R

Picropodophyllin (Standard) AXL1717 (Standard); Picropodophyllotoxin (Standard); PPP (Standard)	IGF-1R Apoptosis Reference Standards	Endocrinology Cancer
Picropodophyllin (Standard) is the analytical standard of Picropodophyllin. This product is intended for research and analytical applications. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.

HY-P99218

Robatumumab Sch 717454; 19D12	IGF-1R	Cancer
Robatumumab (Sch 717454) is an anti-human IGF-1R (insulin-like growth factor receptor-1) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research .

HY-135680

I-OMe-Tyrphostin AG 538 1 Publications Verification I-OMe-AG 538	IGF-1R	Metabolic Disease Cancer
I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells.?I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC₅₀?of 1 μM .

HY-112720

AGL-2263 1 Publications Verification	Insulin Receptor	Metabolic Disease Endocrinology
AGL-2263 is an insulin receptor and insulin-like growth factor (IGF) receptor inhibitor .

HY-153485

Cimdelirsen ISIS 766720; IONIS-GHR-LRx	GHR Small Interfering RNA (siRNA)	Others
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

HY-174655

Human IGF1 mRNA	mRNA	Metabolic Disease
Human IGF1 mRNA encodes the human insulin like growth factor 1 (IGF1) protein which is involved in mediating growth and development.

HY-114095

BML-280 VU0285655-1	Phospholipase TNF Receptor Interleukin Related	Metabolic Disease Inflammation/Immunology Cancer
BML-280 (VU0285655-1) is a potent and selective phospholipase D2 (PLD2) inhibitor. BML-280 has the ability to prevent caspase-3 cleavage and reduction in cell viability induced by high glucose. BML-280 can be used for rheumatoid arthritis research .

HY-P2090A

Angiopeptin TFA	Somatostatin Receptor Adenylate Cyclase	Cardiovascular Disease
Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst₂/sst₅ receptor partial agonist with IC₅₀ values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research .

HY-153485A

Cimdelirsen sodium ISIS 766720 sodium; IONIS-GHR-LRx sodium	GHR Small Interfering RNA (siRNA)	Others
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

HY-13312A

GTx-134	IGF-1R Insulin Receptor Akt Apoptosis	Cancer
GTx-134 is a dual insulin-like growth factor 1 receptor/insulin receptor (IGF-1R/IR) inhibitor with an IC₅₀ values for IGF-1R and IR of 97 and 187 nM respectively. GTx-134 inhibits the autophosphorylation of IGF-1R and its downstream signaling pathway (Akt), thereby blocking the proliferation and survival signals of tumor cells. GTx-134 has broad-spectrum inhibitory activity against multiple myeloma cell lines and can induce apoptosis in sensitive cells. GTx-134 significantly inhibits tumor growth in mice with MM1.S cell transplantation. GTx-134 works in synergy with existing therapies (such as protease preparations, immunomodulators). GTx-134 can be used in high-risk myeloma research .

HY-P2450

Leucinostatin A Antibiotic P168	Fungal Antibiotic	Infection Cancer
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .

HY-P1773

IGF-I (30-41) insulin-like Growth Factor I (30-41)	Insulin Receptor	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

HY-177622

Cibrigirsen	IGF-1R	Metabolic Disease
Cibrigirsen is an antisense oligonucleotide targeted to the insulin-like growth factor I receptor(IGF-1R).

HY-P1773A

IGF-I (30-41) TFA insulin-like Growth Factor I (30-41) TFA	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

HY-162506

IGF-1R inhibitor-3	IGF-1R	Cancer
IGF-1R inhibitor-3 (Compound C11) is an allosteric inhibitor for insulin-like growth factor receptor 1 kinase (IGF-1R), with an IC₅₀ of 0.2 μM .

HY-P1777A

IGF-I (24-41) TFA insulin-like Growth Factor I (24-41) TFA	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .

HY-10438

BMS-577098	IGF-1R	Cancer
BMS-577098 is an orally active and ATP-competitive insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC₅₀ of 0.016 μM. BMS-577098 shows anti-tumor effect .

HY-P2093A

S961 TFA	Insulin Receptor	Metabolic Disease
S961 TFA is an high-affinity and selective insulin receptor (IR) antagonist with IC₅₀s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively .

HY-P991134

Elegrobart	IGF-1R	Inflammation/Immunology
Elegrobart is an immunoglobulin G1-κ monoclonal antibody targeting the human insulin-like growth factor 1 receptor (IGF1R). Elegrobart is promising for research of diseases associated with abnormal IGF1R signaling, especially thyroid eye disease .

HY-P10403

IGFBP-3 peptide	IGF-1R	Inflammation/Immunology Cancer
IGFBP-3 peptide is a 18-amino acid insulin-like growth factor binding protein-3. IGFBP-3 peptide binds Humanin (HY-P1928) and Hyaluronan (HY-B0633A), blocks the interaction of CD44 and hyaluronan .

HY-118046

GSK2163632A	ROCK IGF-1R G Protein-coupled Receptor Kinase (GRK)	Cardiovascular Disease
GSK2163632A is a selective G protein-coupled receptor kinase (GRK) inhibitor that can be used as a probe for studying heart failure and Parkinson's disease. GSK2163632A potently inhibits GRK1 and GRK5, and also inhibits Rho-associated coiled-coil kinase (ROCK) and insulin-like growth factor receptor IGF-1R. GSK2163632A binds to GRK2 in a manner similar to Paroxetine (HY-122272).

HY-P11246

A13:B7-24-GG	RXFP Receptor	Metabolic Disease
A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a K_i value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (K_i = 602.56 nM) and an inhibitory effect on cAMP (EC₅₀) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC₅₀ of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .

HY-174650

Human IGFBP3 mRNA	mRNA	Metabolic Disease
Human IGFBP3 mRNA encodes the human insulin like growth factor binding protein 3 (IGFBP3) protein, a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP3 can form a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.

HY-P2090

Angiopeptin	Somatostatin Receptor Adenylate Cyclase	Cardiovascular Disease
Angiopeptin, a cyclic octapeptide analogue of somatostatin, is a weak sst₂/sst₅ receptor partial agonist with IC₅₀ values of 0.26 nM and 6.92 nM, respectively. Angiopeptin is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin has the potential for coronary atherosclerosis research .

HY-174649

Human IGFBP4 mRNA	mRNA	Metabolic Disease
Human IGFBP4 mRNA encodes the human insulin like growth factor binding protein 4 (IGFBP4) protein, a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 can bind both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

HY-177622A

Cibrigirsen sodium	IGF-1R	Metabolic Disease
Cibrigirsen sodium is an antisense oligonucleotide targeted to the insulin-like growth factor I receptor(IGF-1R).

HY-174652

Human IGFBP1 mRNA	mRNA	Metabolic Disease
Human IGFBP1 mRNA encodes the human insulin like growth factor binding protein 1 (IGFBP1) protein, a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP1 is important in cell migration and metabolism.

HY-B0025R

Voglibose (Standard)	Reference Standards Glycosidase	Metabolic Disease
Voglibose (Standard) is the analytical standard of Voglibose. This product is intended for research and analytical applications. Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis[1].

HY-15494S1

Picropodophyllin-d6 AXL1717-d₆; Picropodophyllotoxin-d₆; PPP-d₆	Isotope-Labeled Compounds IGF-1R Apoptosis	Endocrinology Cancer
Picropodophyllin-d₆ (AXL1717-d₆) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.

Cat. No.	Product Name

HY-L101

Anti-Liver Cancer Compound Library

2,838 compounds

Liver cancer is one of the leading malignancies which occupies the second position in cancer deaths worldwide, becoming serious threat to human health. Hepatocellular carcinoma (HCC), also known as hepatoma is the most common type accounting for approximately 90% of all liver cancers.

Current evidence indicates that during hepatocarcinogenesis, two main pathogenic mechanisms prevail: (1) cirrhosis associated with hepatic regeneration after tissue damage caused by hepatitis infection, toxins or metabolic influences, and (2) mutations occurring in single or multiple oncogenes or tumor suppressor genes. Both mechanisms have been linked with alterations in several important cellular signaling pathways. These include the RAF/MEK/ERK pathway, PI3K/AKT/mTOR pathway, WNT/b-catenin pathway, insulin-like growth factor pathway, c-MET/HGFR pathway , etc.

MCE offers a unique collection of 2,838 compounds with identified and potential anti-liver cancer activity. MCE anti-liver cancer compound library is a useful tool for anti-liver cancer drugs screening and other related research.

Cat. No.	Product Name	Target	Research Area

HY-P2093

S961 5+ Cited Publications	Insulin Receptor	Metabolic Disease
S961 is an high-affinity and selective insulin receptor (IR) antagonist with IC₅₀s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively .

HY-P2093B

S961 acetate 5+ Cited Publications	Insulin Receptor	Metabolic Disease
S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC₅₀s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively .

HY-108905

Mecasermin Human IGF-I; FK 780	IGF-1R	Metabolic Disease
Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .

HY-P1777

IGF-I (24-41) insulin-like Growth Factor I (24-41)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .

HY-117483

Gly-Pro-Glu	iGluR	Neurological Disease
Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC₅₀ value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection .

HY-P2090A

Angiopeptin TFA	Somatostatin Receptor Adenylate Cyclase	Cardiovascular Disease
Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst₂/sst₅ receptor partial agonist with IC₅₀ values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research .

HY-P1773

IGF-I (30-41) insulin-like Growth Factor I (30-41)	Insulin Receptor	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

HY-P1773A

IGF-I (30-41) TFA insulin-like Growth Factor I (30-41) TFA	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

HY-P1777A

IGF-I (24-41) TFA insulin-like Growth Factor I (24-41) TFA	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .

HY-P2093A

S961 TFA	Insulin Receptor	Metabolic Disease
S961 TFA is an high-affinity and selective insulin receptor (IR) antagonist with IC₅₀s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively .

HY-P4657

Human Growth Hormone (1-43)	Peptides	Endocrinology
Human Growth Hormone (1-43) is an N-terminal fragment of human growth hormone with specific and pronounced insulin-like activity. Human Growth Hormone (1-43) can be used to study the function and metabolic pathways of growth hormone, a potential obesity-related factor .

HY-P10403

IGFBP-3 peptide	IGF-1R	Inflammation/Immunology Cancer
IGFBP-3 peptide is a 18-amino acid insulin-like growth factor binding protein-3. IGFBP-3 peptide binds Humanin (HY-P1928) and Hyaluronan (HY-B0633A), blocks the interaction of CD44 and hyaluronan .

HY-P11246

A13:B7-24-GG	RXFP Receptor	Metabolic Disease
A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a K_i value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (K_i = 602.56 nM) and an inhibitory effect on cAMP (EC₅₀) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC₅₀ of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .

HY-P2090

Angiopeptin	Somatostatin Receptor Adenylate Cyclase	Cardiovascular Disease
Angiopeptin, a cyclic octapeptide analogue of somatostatin, is a weak sst₂/sst₅ receptor partial agonist with IC₅₀ values of 0.26 nM and 6.92 nM, respectively. Angiopeptin is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin has the potential for coronary atherosclerosis research .

HY-P11620

H-Asn-Pro-Glu-Tyr(PO3H2)-OH	Drug Derivative	Others
H-Asn-Pro-Glu-Tyr(PO3H2)-OH is a phosphorylated peptide derivative of the tetramine motif Asn-Pro-Glu-Tyr (NPEY), and is a substrate binding domain common to the insulin-like growth factor-I receptor (IGF-IR) and the insulin receptor (IR).

Cat. No.	Product Name	Target	Research Area	Image

HY-P99294

Ganitumab 1 Publications Verification AMG 479; Human Anti-IGF1R Recombinant Antibody	IGF-1R	Cancer
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the *human type 1 insulin-like* growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D**=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-P99197

Figitumumab CP-751871	IGF-1R	Cancer
Figitumumab (CP-751871) is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC₅₀ of 1.8 nM .

HY-P99218

Robatumumab Sch 717454; 19D12	IGF-1R	Cancer
Robatumumab (Sch 717454) is an anti-human IGF-1R (insulin-like growth factor receptor-1) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research .

HY-P991134

Elegrobart	IGF-1R	Inflammation/Immunology
Elegrobart is an immunoglobulin G1-κ monoclonal antibody targeting the human insulin-like growth factor 1 receptor (IGF1R). Elegrobart is promising for research of diseases associated with abnormal IGF1R signaling, especially thyroid eye disease .

HY-P992108

Efadirelaxin alfa RELAX10	RXFP Receptor Akt NO Synthase VEGFR	Cardiovascular Disease
Efadirelaxin alfa (RELAX10) is a highly selective agonist of *relaxin/insulin-like* family peptide receptor RXFP1. After subcutaneous administration in animal experiments, Efadirelaxin alfa exhibits a significantly prolonged terminal half-life (7 days in mice, 3.75 days in rats), and shows no activity against related receptors such as RXFP2 and RXFP3. Efadirelaxin alfa has significant anti-cardiac hypertrophy and anti-fibrotic effects. Efadirelaxin alfa effectively attenuates and reverses cardiac hypertrophy and collagen deposition by regulating the TGF-β1/Smad2 and AKT/eNOS** signaling pathways. Efadirelaxin alfa improves cardiac systolic function without causing fluctuations in blood pressure or heart rate, demonstrating favorable safety. Efadirelaxin alfa is currently mainly used in studies related to heart failure .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-15494

Picropodophyllin 25+ Cited Publications AXL1717; Picropodophyllotoxin; PPP	Classification of Application Fields Lignans Dysosma versipellis (Hance) M. Cheng ex Ying Phenylpropanoids Plants Berberidaceae Disease Research Fields Endocrinology Source Classification	IGF-1R Apoptosis
Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC₅₀ of 1 nM.

HY-W010128

6-(Dimethylamino)purine 6-Dimethylaminopurine; 6-DMAP	Classification of Application Fields Other Diseases Disease Research Fields	CDK DNA/RNA Synthesis Apoptosis
6-(Dimethylamino) purine (6-Dimethylaminopurine) is a serine threonine protein kinase inhibitor. 6-(Dimethylamino) purine can inhibit prolactin induced expression of lactoprotein genes in rabbit mammary gland cells. 6-(Dimethylamino) purine can affect the maturation of mammalian oocytes. 6-(Dimethylamino) purine can lead to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induce apoptosis in lymphoma cells (apoptosis) .

HY-B0025

Voglibose 1 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Metabolic Disease Disease Research Fields Saccharides Source Classification	Glycosidase
Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis .

HY-15494R

Picropodophyllin (Standard) AXL1717 (Standard); Picropodophyllotoxin (Standard); PPP (Standard)	Structural Classification Lignans Dysosma versipellis (Hance) M. Cheng ex Ying Phenylpropanoids Plants Berberidaceae Source Classification	IGF-1R Apoptosis Reference Standards
Picropodophyllin (Standard) is the analytical standard of Picropodophyllin. This product is intended for research and analytical applications. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.

HY-P2450

Leucinostatin A Antibiotic P168	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Fungal Antibiotic
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .

HY-B0025R

Voglibose (Standard)	Structural Classification Microorganisms Saccharides Source Classification	Reference Standards Glycosidase
Voglibose (Standard) is the analytical standard of Voglibose. This product is intended for research and analytical applications. Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis[1].

Species:	Human (35) Rhesus Macaque (2) Rat (2) Mouse (14) Cynomolgus (3) Pig (1) Canine (2)
Tag:	T7 (1) SUMO (1) His (42) Tag Free (7) Avi (4) GST (3) Flag (1) Fc (10)
Source:	HEK293 (38) Sf9 insect cells (3) P. pastoris (3) E. coli (16)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70176

	Insulin-like 3/INSL3 Protein, Human (HEK293, His) rHuinsulin-like 3/INSL3, His; insulin-like 3; Leydig insulin-like peptide; Relaxin-like factor; INSL3; RLF; RLNL	Human	HEK293
	Insulin-like 3/INSL3 Protein, Human (HEK293, His) is the recombinant human-derived Insulin-like 3/INSL3 protein, expressed by HEK293, with C-His labeled tag.

HY-P70833

	INSL4 Protein, Human (HEK293, His) Early Placenta insulin-like Peptide; EPIL; insulin-like Peptide 4; Placentin; INSL4	Human	HEK293
	The INSL4 protein plays a potentially critical role in the regulation of trophoblast development and bone formation. The specific mechanism of trophoblast development deserves further study. INSL4 Protein, Human (HEK293, His) is the recombinant human-derived INSL4 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P701241

	IGF-I Protein, Salmon IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C	Others	E. coli
	IGF-I protein is similar to insulin and exerts effective growth-promoting activity as a ligand of IGF1R. Binding to the α subunit of IGF1R activates intrinsic tyrosine kinase, triggering autophosphorylation of the β subunit. IGF-I Protein, Salmon is the recombinant IGF-I protein, expressed by E. coli , with tag free.

HY-P70698

	IGF-I/IGF-1 Protein, Mouse (His) 4 Publications Verification IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C	Mouse	E. coli
	IGF-I/IGF-1 Protein, Mouse (His) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. IGF1 also mediates neuroprotective mechanism.

HY-P70698A

	IGF-I/IGF-1 Protein, Mouse (N-His) IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C	Mouse	E. coli
	The IGF-I/IGF-1 protein is structurally similar to insulin and has potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, exceeding the efficacy of insulin at lower concentrations. IGF-I/IGF-1 Protein, Mouse (N-His) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P76455

	INSL6 Protein, Human (HEK293, His) insulin-like peptide INSL6; Relaxin/insulin-like factor 1; INSL6; RIF1	Human	HEK293
	The INSL6 protein plays a crucial role in sperm development and fertilization, highlighting its importance in male reproductive biology. Its potential function in promoting sperm development and successful fertilization emphasizes its importance in reproductive physiology. INSL6 Protein, Human (HEK293, His) is the recombinant human-derived INSL6 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73906

	IGF2 Protein, Human (P.pastoris) insulin-like growth factor II; IGF-II; Preptin; IGF2; PP1446	Human	P. pastoris
	The IGF2 protein is an important member of the insulin-like growth factor family and plays an important role in mammalian growth, fetoplacental development, and adult glucose metabolism. Regulated by placental prolactin, affecting tissue differentiation. IGF2 Protein, Human (P.pastoris) is the recombinant human-derived IGF2 protein, expressed by P. pastoris , with tag free.

HY-P76410

	IGFBP-5 Protein, Canine (HEK293, Fc) insulin-like growth factor-binding protein 5; IGFBP5	Canine	HEK293
	IGFBP-5 is only one of a family of six IGFBPs. IGFBP-5 is a 29 kDa phosphorylated and glycosylated protein, which is secreted by a wide variety of cell types during different growth conditions. IGFBP-5, the most conserved IGFBP, is the major protein secreted by skeletal muscles. IGFBP-5 Protein, Canine (HEK293, Fc) is the recombinant canine-derived IGFBP-5 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74848

	IGFBP-1 Protein, Rhesus Macaque (HEK293, His) insulin-like growth factor-binding protein 1; IGFBP1	Rhesus Macaque	HEK293
	IGFBP-1 Protein, a member of the insulin-like growth factor-binding protein (IGFBP) family, extends IGFs' half-life and modulates their growth-promoting effects on cell culture, inhibiting or stimulating these responses. Crucially, it alters the interaction between IGFs and their cell surface receptors and promotes cell migration. Notably versatile, IGFBP-1 shows equal binding affinity for both IGF1 and IGF2, underscoring its diverse role in modulating the biological activities of insulin-like growth factors. IGFBP-1 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IGFBP-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700241AF

	Animal-Free IGF-I Protein, Pig (His) insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Pig	E. coli
	The IGF-I protein is structurally similar to insulin and has excellent growth-promoting activity. As a potential physiological regulator, it affects [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Animal-Free IGF-I Protein, Pig (His) is the recombinant pig-derived animal-FreeIGF-I protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P74849

	IGFBP-1 Protein, Canine (HEK293, His) insulin-like growth factor-binding protein 1; PP12; IBP-1;	Canine	HEK293
	IGFBP-1 Protein is a member of the insulin-like growth factor binding protein (IGFBP) family that binds insulin-like growth factor (IGFs) I and II to extend the half-life of IGFs. IGFBP-1 inhibits proliferation, invasion, migration and apoptosis of HTR-8/SVneo cells by inducing MMP-26 expression. IGFBP1 may be a new prognostic factor and a target of molecular targeted therapy for gastric cancer. IGFBP-1 Protein, Canine (HEK293, His) is the recombinant canine-derived IGFBP-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74843

	IGF-I/IGF-1 Protein, Mouse (P.pastoris) insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Mouse	P. pastoris
	IGF-I/IGF-1 Protein, part of the insulin family, is highlighted. IGF-I/IGF-1 Protein, Mouse (P.pastoris) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with tag free.

HY-P73136

	IGF-I/IGF-1 Protein, Human (HEK293, hFc) insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Human	HEK293
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P73140

	IGFBP-5 Protein, Human (sf9, His) insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IBP5	Human	Sf9 insect cells
	The IGFBP-5 protein regulates insulin-like growth factor (IGF) and extends its lifespan. It can inhibit or stimulate the growth-promoting effect of IGF, showing its dual regulatory function. IGFBP-5 Protein, Human (sf9, His) is the recombinant human-derived IGFBP-5 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P73141

	IGFBP-6 Protein, Human (HEK293, His) insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IBP6	Human	HEK293
	IGFBP-6 protein is an important IGFBP member that regulates insulin-like growth factor (IGF) by changing its interaction with cell surface receptors, thereby affecting IGF-induced growth responses. In addition to regulating IGF signaling, IGFBP-6 also activates the MAPK pathway and induces cell migration. IGFBP-6 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-6 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73142

	IGFBP-7 Protein, Human (HEK293, Fc) insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF	Human	HEK293
	IGFBP-7 Protein, with relatively low IGF-I and IGF-II affinity, stimulates prostacyclin (PGI2) production and enhances cell adhesion. The significance of its interaction with VPS24/CHMP3 remains uncertain and warrants further investigation. IGFBP-7 Protein, Human (HEK293, Fc) is the recombinant human-derived IGFBP-7 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73905

	IGFBP-6 Protein, Rat (HEK293, His) insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IBP6	Rat	HEK293
	IGFBP-6 protein modulates IGFs' activity, extending their half-life and exhibiting dual regulatory capacity.It activates the MAPK pathway, induces cell migration, and interacts with PHB2.These diverse functions emphasize IGFBP-6's multifaceted role in cellular responses related to growth regulation, signaling, and migration.IGFBP-6 Protein, Rat (HEK293, His) is the recombinant rat-derived IGFBP-6 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77394

	IGFBP-5 Protein, Cynomolgus (HEK293, His) insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IBP5	Cynomolgus	HEK293
	IGFBP-5 protein modulates IGFs, extending their life span and regulating their growth effects. It inhibits or stimulates IGFs, showing its dual function. By altering IGFs' interaction with cell receptors, IGFBP-5 fine-tunes growth-associated signaling pathways, governing cellular responses. This interplay reveals IGFBP-5's multifaceted role in cellular growth and proliferation. IGFBP-5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-5 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73138

	IGFBP-3 Protein, Human (HEK293, His) insulin-like growth factor-binding protein 3; IGF-BP3; IBP-3; IGFBP-3	Human	HEK293
	IGFBP-3 protein is a part of IGFBP that significantly prolongs IGF half-life and modulates growth effects in cell culture. It inhibits or stimulates IGF-induced cellular responses by changing the kinetics of interaction with cell surface receptors. IGFBP-3 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-3 protein, expressed by HEK293 , with N-His labeled tag.

HY-P74844

	IGFBP-7 Protein, Mouse (HEK293, Fc) IBP-7; IGFBP7; IGFBP-7v; insulin-like growth factor binding protein 7	Mouse	HEK293
	IGFBP-7 Protein is a member of the insulin-like growth factor binding protein (IGFBP) Family. The major function of IGFBP-7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 exhibits a relatively low affinity for binding to both IGF-I and IGF-II. Furthermore, it has the capacity to stimulate the production of prostacyclin (PGI2) and enhance cell adhesion. IGFBP-7 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-7 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74845

	IGFBP-4 Protein, Mouse (HEK293, His) BP-4; HT29-IGFBP; IBP4; insulin-like growth factor-binding protein 4	Mouse	HEK293
	IGFBP-4 protein modulates IGFs' activity and can either inhibit or stimulate their growth-promoting effects. It alters the interaction between IGFs and their receptors, with a preference for binding to IGF2. This highlights the nuanced role of IGFBP-4 in fine-tuning IGF-mediated cellular responses. IGFBP-4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74846

	IGFBP-2 Protein, Mouse (HEK293, His) IBP-2; insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53	Mouse	HEK293
	IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74847

	IGFBP-2 Protein, Mouse (HEK293, Fc) IBP-2; insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53	Mouse	HEK293
	IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P700185AF

	Animal-Free IGF-II Protein, Mouse (His) insulin-like growth factor 2; Multiplication-stimulating polypeptide; IGF-II; Igf-2; Igf2	Mouse	E. coli
	The IGF-II protein plays a crucial role in glucose-mediated insulin secretion, acting together with insulin as a physiological amplifier. Furthermore, it exhibits osteogenic properties by enhancing osteoblast mitotic activity through phosphorylation of MAPK1 and MAPK3. Animal-Free IGF-II Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIGF-II protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P703840

	IGFBP-3 Protein, Cynomolgus (HEK293, His) insulin-like growth factor-binding protein 3; IGF-BP3; IBP-3; IGFBP-3	Cynomolgus	HEK293
	IGFBP-3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-3 protein, expressed by HEK293, with N-His tag.

HY-P72606

	IGF-I R Protein, Human (HEK293, His) insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P703906

	IGFBP-7 Protein, Human (Biotinylated, HEK293, hFc, Avi) insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF	Human	HEK293
	IGFBP-7 Protein, with relatively low IGF-I and IGF-II affinity, stimulates prostacyclin (PGI2) production and enhances cell adhesion. The significance of its interaction with VPS24/CHMP3 remains uncertain and warrants further investigation. IGFBP-7 Protein, Human (Biotinylated, HEK293, hFc, Avi) is the recombinant human-derived IGFBP-7 protein, expressed by HEK293, with Avi and C-hFc labeled tag.

HY-P704676

	IGF-I R Protein, Human (HEK293, Fc) insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, Fc) is the recombinant human-derived IGF-I R protein, expressed by HEK293, with C-hFc labeled tag.

HY-P705032

	IGFBP-7 Protein, Human (Biotinylated, HEK293, His-Avi) insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF	Human	HEK293

HY-P70357

	IGFBP-6 Protein, Mouse (HEK293, His) rMuinsulin-like growth factor-binding protein 6/IGFBP-6, His; insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6; Igfbp6; IBP6; IGF binding protein 6; insulin-like growth factor-binding protein 6	Mouse	HEK293
	IGFBP-6 protein can extend the half-life of IGF and regulate its effects. It can inhibit or stimulate the growth-promoting effects of IGF. IGFBP-6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-6 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P74442

	IGF-I R Protein, Human (HEK293, His, solution) insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His, solution) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-His labeled tag.

HY-P77393

	IGFBP-4 Protein, Cynomolgus (HEK293, His) insulin-like growth factor-binding protein 4; IGF-BP-4; IBP-4; IGFBP-4; BP4	Cynomolgus	HEK293
	IGFBP-4 protein lacks essential conserved residue(s) for propagating feature annotation. IGFBP-4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P703905

	IGFBP-7 Protein, Human (HEK293, K95R, His) insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF	Human	HEK293
	IGFBP-7 Protein, with relatively low IGF-I and IGF-II affinity, stimulates prostacyclin (PGI2) production and enhances cell adhesion. The significance of its interaction with VPS24/CHMP3 remains uncertain and warrants further investigation. IGFBP-7 Protein, Human (HEK293, K95R, His) is the recombinant human-derived IGFBP-7 protein, expressed by HEK293, with N-His labeled tag.

HY-P73137

	IGF-I R Protein, Human (Active, sf9, His-GST) insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R	Human	Sf9 insect cells
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (sf9, His-GST) is the recombinant human-derived IGF-I R protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P70788

	IGF-I/IGF-1 Protein, Human (G49-A118) Maximum Cited Publications 6 Publications Verification insulin-like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (G49-A118) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by E. coli , with tag free.

HY-P700478

	IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) 1 Publications Verification insulin-like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	P. pastoris
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P700256

	IGFBP-1 Protein, Mouse (SUMO, His) insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12	Mouse	E. coli
	The IGFBP-1 protein is an insulin-like growth factor binding protein that extends the half-life of IGF and modulates its growth-promoting effects in cell cultures, thereby inhibiting or stimulating these responses. Crucially, it alters the interaction between IGF and its cell surface receptors and promotes cell migration. IGFBP-1 Protein, Mouse (SUMO, His) is the recombinant mouse-derived IGFBP-1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P72608

	IGFBP-1 Protein, Human (HEK293, His) insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12	Human	HEK293
	IGFBP-1 protein extends the half-life of IGFs and modulates their activity. It can inhibit or stimulate IGFs' growth-promoting effects, altering their interaction with receptors and fine-tuning signaling pathways. IGFBP-1 promotes cell migration and binds to both IGF1 and IGF2, highlighting its versatile role in modulating IGF signaling pathways. IGFBP-1 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72256

	IGF-I R Protein, Human (His) CD221; CD221 antigen ; IGF 1 receptor; IGF 1R; IGF I receptor; IGF-I receptor; Igf1r; IGF1R_HUMAN; IGFIR; IGFIRC; IGFR; insulin like growth factor 1 receptor; insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor beta chain; insulin-like growth factor I receptor; JTK13; MGC142170; MGC142172; MGC18216; Soluble IGF1R variant 1; Soluble IGF1R variant 2	Human	E. coli
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (His) is the recombinant human-derived IGF-I R protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70783

	LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) 2 Publications Verification Long R3 IGF-I; insulin-like growth factor I; MGF; Somatomedin-C; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free and E51R mutation.

HY-P76409

	IGFBP-2 Protein, Rhesus Macaque (HEK293, His) insulin-like growth factor 2 mRNA-binding protein 2; IMP-2; IGF2BP2; VICKZ2	Rhesus Macaque	HEK293
	IGFBP‐2 is a member of a family of six insulin‐like growth factor (IGF) binding proteins. IGFBP-2 is the second most abundant IGFBP in the circulation and binds IGF-II with higher affinity than IGF-I. IGFBP-2 has been implicated in the regulation of IGF activity in most tissues and organs. IGFBP-2 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700093AF

	Animal-Free IGF-I/IGF-1 Protein, Human (His) 1 Publications Verification Somatamedin C; IGF-IA; insulin-like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. Animal-Free IGF-I/IGF-1 Protein, Human (His) is the recombinant human-derived animal-FreeIGF-I/IGF-1 protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

HY-P70783G

	GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) Long R3 IGF-I; insulin-like growth factor I; MGF; Somatomedin-C; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free.

HY-P702849

	IGFBP-1 Protein, Mouse (HEK293, His) Igfbp1; Igfbp-1; insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1	Mouse	HEK293
	The IGFBP-1 protein is an insulin-like growth factor binding protein that extends the half-life of IGF and modulates its growth-promoting effects in cell cultures, thereby inhibiting or stimulating these responses. Crucially, it alters the interaction between IGF and its cell surface receptors and promotes cell migration. IGFBP-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-1 protein, expressed by HEK293 , with C-10*His tag.

HY-P704374

	IGF-I/IGF-1 Protein, Human (HEK293, N-His) 1 Publications Verification Somatamedin C; IGF-IA; insulin-like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	HEK293
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (HEK293, N-His) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by HEK293, with N-His labeled tag.

HY-P74850

	IGF2BP2 Protein, Human (sf9, His-GST) insulin-like growth factor 2 mRNA-binding protein 2; IMP-2; IGF2BP2; VICKZ2	Human	Sf9 insect cells
	The IGF2BP2 protein is an RNA-binding factor that coordinates the recruitment of target transcripts into cytoplasmic mRNP, promoting mRNA transport and transient storage. It regulates the contact of target transcripts with the translation machinery and protects them from microRNA-mediated degradation. IGF2BP2 Protein, Human (sf9, His-GST) is the recombinant human-derived IGF2BP2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P72378

	IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi) 1 Publications Verification insulin-like Growth Factor-Binding Protein 5; IBP-5; IGF-Binding Protein 5; IGFBP-5; IGFBP5; IBP5	Human	HEK293
	The IGFBP-5 protein regulates insulin-like growth factor (IGF) and extends its lifespan. It can inhibit or stimulate the growth-promoting effect of IGF, showing its dual regulatory function. IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IGFBP-5 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

HY-P705031

	IGFBP-5 Protein, Human (Biotinylated, HEK293, Avi-Flag, His) insulin-like Growth Factor-Binding Protein 5; IBP-5; IGF-Binding Protein 5; IGFBP-5; IGFBP5; IBP5	Human	HEK293

HY-P70726

	IGFBP-7 Protein, Human (HEK293, His) 1 Publications Verification insulin-like growth factor-binding protein 7; IGFBP7; IGF-binding protein 7; IGFBP-rP1; MAC25 protein; Tumor-derived adhesion factor; TAF	Human	HEK293
	IGFBP-7 Protein, with relatively low IGF-I and IGF-II affinity, stimulates prostacyclin (PGI2) production and enhances cell adhesion. The significance of its interaction with VPS24/CHMP3 remains uncertain and warrants further investigation. IGFBP-7 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70858

	IGFBP-7 Protein, Mouse (HEK293, His) insulin-like growth factor-binding protein 7; IGFBP7; IGF-binding protein 7; IGFBP-rP1; MAC25 protein; Tumor-derived adhesion factor; TAF	Mouse	HEK293
	The IGFBP-7 protein has moderate affinity to bind to IGF-I and IGF-II and significantly stimulates the production of prostacyclin (PGI2). In addition to its interaction with insulin-like growth factors, IGFBP-7 also contributes to cell adhesion, suggesting its role in adhesion-related cellular processes and potential effects on cell-matrix interactions. IGFBP-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-7 protein, expressed by HEK293 , with C-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-15494S1

Picropodophyllin-d6
Picropodophyllin-d₆ (AXL1717-d₆) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.

HY-15494S

Picropodophyllin-d3
Picropodophyllin-d₃ (AXL1717-d₃; Picropodophyllotoxin-d₃; PPP-d₃) is the deuterium labeled Picropodophyllin (HY-15494). Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC₅₀ of 1 nM.

HY-W747751

Sorbic acid-13C2

Sorbic acid- ¹³C₂ is the ¹³C-labeled Sorbic acid (HY-N0626). Sorbic acid is an effective, safe, and non-toxic food preservative. It can effectively inhibit most molds, yeasts, and certain bacteria. Sorbic acid is orally active and can enhance the growth performance of economically important animals (Duroc × Landrace × Yorkshire piglets) by activating the insulin-like growth factor system (IGF), and it can also lead to lipid accumulation by disrupting lipid clearance pathways .

HY-W749516

Voglibose-13C3

Voglibose- ¹³C₃ is the ¹³C-labeled Voglibose (HY-B0025). Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis.

Host:	Mouse (4) Rabbit (24)
Reactivity:	Human (27) Rat (14) Mouse (17) Dog (1)
Application:	IHC-P (21) ICC/IF (16) IF-Tissue (2) IP (10) IHC-F (4) WB (26) FC (3) ELISA (9)
Isotype:	IgG (24) IgG/Kappa (1)
Conjugation:	Non-conjugated (28) Biotin (4)
Clonality:	Polyclonal (3) Monoclonal (18) Recombinant (11)
Modification:	Phosphorylated (2) Unmodified (20)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P810689

	INSL4 Antibody Early placenta insulin-like peptide, EPIL, insulin-like peptide 4, Placentin, INSL4	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	INSL4 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to INSL4.

HY-P81496

	INSL3 Antibody (YA1241) INSL3; RLF, RLNL; insulin-like 3; Leydig insulin-like peptide (Ley-I-L); Relaxin-like factor	IHC-P	Human
	INSL3 Antibody (YA1241) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to INSL3.

HY-P81496A

	INSL3 Antibody (YA1241)(PBS only) INSL3; RLF, RLNL; insulin-like 3; Leydig insulin-like peptide (Ley-I-L); Relaxin-like factor	IHC-P	Human
	INSL3 Antibody (YA1241) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to INSL3.

HY-P80717

	IGF1 Receptor Antibody (YA351) IGF1R; insulin-like growth factor 1 receptor; insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IHC-P	Human
	IGF1 Receptor Antibody (YA351) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF1 Receptor.

HY-P85213

	IGF1 Receptor Antibody (YA4905) IGF1R; insulin-like growth factor 1 receptor; insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IHC-P, ICC/IF, ELISA	Human
	IGF1 Receptor Antibody (YA4905) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to IGF1 Receptor.

HY-P85214

	IGF1 Receptor Antibody (YA4906) IGF1R; insulin-like growth factor 1 receptor; insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IHC-P, ICC/IF, ELISA	Human
	IGF1 Receptor Antibody (YA4906) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to IGF1 Receptor.

HY-P86629

	IGF1 Receptor Antibody (YA6321) IGF1R; insulin-like growth factor 1 receptor; insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IHC-P, ICC/IF, IP, ELISA	Human
	IGF1 Receptor Antibody (YA6321) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF1 Receptor.

HY-P80717A

	IGF1 Receptor Antibody (YA351)(PBS only) IGF1R; insulin-like growth factor 1 receptor; insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IHC-P	Human
	IGF1 Receptor Antibody (YA351) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF1 Receptor.

HY-P80825

	Phospho-IGF1 Receptor (Tyr1166) Antibody (YA186) IGF1R; insulin-like growth factor 1 receptor; insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IP	Human, Mouse, Rat
	Phospho-IGF1 Receptor (Tyr1166) Antibody (YA186) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-IGF1 Receptor (Tyr1166).

HY-P80825A

	Phospho-IGF1 Receptor (Tyr1166) Antibody (YA186)(PBS only) IGF1R; insulin-like growth factor 1 receptor; insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IP	Human, Mouse, Rat
	Phospho-IGF1 Receptor (Tyr1166) Antibody (YA186) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-IGF1 Receptor (Tyr1166).

HY-P86076

	*Phospho-IGF1R(Tyr1135/1136)/Insulin* Receptor β(Tyr1150/1151) Antibody (YA5768)** IGF1R; insulin-like growth factor 1 receptor; insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221; INSR; insulin receptor; IR; CD antigen CD220	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-IGF1R(Tyr1135/1136)/Insulin Receptor β(Tyr1150/1151) Antibody (YA5768) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-IGF1R(Tyr1135/1136)/Insulin Receptor β(Tyr1150/1151).

HY-P81754

	IGF2R Antibody (YA1499) IGF2R; MPRI; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; insulin-like growth factor 2 receptor; insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	IGF2R Antibody (YA1499) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2R.

HY-P81844

	IGFBP2 Antibody (YA1589) IGFBP2; BP2; IBP2; insulin-like growth factor-binding protein 2; IBP-2; IGF-binding protein 2; IGFBP-2	WB, IHC-P	Human
	IGFBP2 Antibody (YA1589) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGFBP2.

HY-P85212

	IGFBP2 Antibody (YA4904) IGFBP2; BP2; IBP2; insulin-like growth factor-binding protein 2; IBP-2; IGF-binding protein 2; IGFBP-2	WB, IHC-P, ICC/IF, ELISA	Human
	IGFBP2 Antibody (YA4904) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to IGFBP2.

HY-P83326

	IGF2BP1 Antibody (YA3071) insulin-like growth factor 2 mRNA binding protein 1; IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1	WB, IHC-P, IP	Human, Mouse
	IGF2BP1 Antibody (YA3071) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2BP1.

HY-P83326A

	IGF2BP1 Antibody (YA3071)(PBS only) insulin-like growth factor 2 mRNA binding protein 1; IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1	WB, IHC-P, IP	Human, Mouse
	IGF2BP1 Antibody (YA3071) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2BP1.

HY-P82665

	IGFBP1 Antibody (YA2410) IGFBP1; IBP1; insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; Placental protein 12; PP12	WB	Human, Mouse, Rat
	IGFBP1 Antibody (YA2410) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGFBP1.

HY-P86582

	CTGF Antibody (YA6274) Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8;	WB, IP, ELISA	Human, Mouse, Rat
	CTGF Antibody (YA6274) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CTGF.

HY-P81103

	CTGF Antibody CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.	WB, ELISA	Mouse, Rat
	CTGF Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CTGF.

HY-P83334

	IGFBP7 Antibody (YA3079) IGFBP7; MAC25; PSF; insulin-like growth factor-binding protein 7; IBP-7; IGF-binding protein 7; IGFBP-7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	IGFBP7 Antibody (YA3079) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGFBP7.

HY-P83334A

	IGFBP7 Antibody (YA3079)(PBS only) IGFBP7; MAC25; PSF; insulin-like growth factor-binding protein 7; IBP-7; IGF-binding protein 7; IGFBP-7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	IGFBP7 Antibody (YA3079) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGFBP7.

HY-P81112

	IGF1 Antibody IBP1; IGF 1; IGF I; IGF-1; IGF IA; IGF IB; IGF1; IGFI; IGFIA; insulin like growth factor 1 (somatomedin C); Full=insulin-like growth factor I; insulin like Growth Factor 1; insulin like growth factor IA; insulin like growth factor IB; Mechano growth factor; MGF; Mechano growth factor; MGF; Somatomedia C; Somatomedin C; IGF1_HUMAN. IGF-I;	WB, IHC-P, IHC-F, ICC/IF, ELISA	Human, Mouse, Rat, Dog
	IGF1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to IGF1.

HY-P82288

	IGF2BP2 Antibody (YA2033) IGF2BP2; IMP2; VICKZ2; insulin-like growth factor 2 mRNA-binding protein 2; IGF2 mRNA-binding protein 2; IMP-2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	IGF2BP2 Antibody (YA2033) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2BP2.

HY-P82288A

	IGF2BP2 Antibody (YA2033)(PBS only) IGF2BP2; IMP2; VICKZ2; insulin-like growth factor 2 mRNA-binding protein 2; IGF2 mRNA-binding protein 2; IMP-2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	IGF2BP2 Antibody (YA2033) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2BP2.

HY-P85226

	IMP-3 Antibody (YA4918) IGF2BP3; IMP3; KOC1; VICKZ3; insulin-like growth factor 2 mRNA-binding protein 3; IGF2 mRNA-binding protein 3; IMP-3; IGF-II mRNA-binding protein 3; KH domain-containing protein overexpressed in cancer; hKOC; VICKZ family member 3	WB, ICC/IF, IP, FC, IHC-P, IHC-F, IF-Tissue	Human
	IMP-3 Antibody (YA4918) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to IMP-3.

HY-P85583

	IMP3 Antibody (YA5275) Cancer/testis antigen 98; CT98; DKFZp686F1078; hKOC; IF2B3_HUMAN; IGF II mRNA binding protein 3; IGF-II mRNA-binding protein 3; IGF2 mRNA binding protein 3; IGF2 mRNA-binding protein 3; IGF2BP3; IMP 3; IMP-3; insulin like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; KOC 1; KOC1; VICKZ 3; VICKZ family member 3; VICKZ3.	IHC-P, WB, ICC/IF, ELISA	Human, Mouse
	IMP3 Antibody (YA5275) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to IMP3.

HY-P86830

	CYR61/CCN1 Antibody (YA6523) 3CH61 antibody; CCN 1 antibody; CCN family member 1 antibody; CCN1 antibody; CYR 61 antibody; Cyr61 antibody; CYR61 protein antibody; CYR61_HUMAN antibody; Cysteine rich angiogenic inducer 61 antibody; Cysteine rich heparin binding protein 61 antibody; 3CH61 antibody; CCN 1 antibody; CCN family member 1 antibody; CCN1 antibody; CYR 61 antibody; Cyr61 antibody; CYR61 protein antibody; CYR61_HUMAN antibody; Cysteine rich angiogenic inducer 61 antibody; Cysteine rich heparin binding protein 61 antibody; Cysteine-rich angiogenic inducer 61 antibody; GIG 1 antibody; GIG1 antibody; IBP-10 antibody; IGF-binding protein 10 antibody; Igfbp 10 antibody; IGFBP-10 antibody; Igfbp10 antibody; insulin like growth factor binding protein 10 antibody; insulin-like growth factor-binding protein 10 antibody; Protein CYR61 antibody; Protein GIG1 antibody;	WB, ICC/IF, IHC-P, IF-Tissue	Human
	CYR61/CCN1 Antibody (YA6523) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CYR61/CCN1.

HY-P80724

	IMP3 Antibody Cancer/testis antigen 98; CT98; DKFZp686F1078; hKOC; IF2B3_HUMAN; IGF II mRNA binding protein 3; IGF-II mRNA-binding protein 3; IGF2 mRNA binding protein 3; IGF2 mRNA-binding protein 3; IGF2BP3; IMP 3; IMP-3; insulin like growth factor 2 mRNA binding prot	WB, ICC/IF, IP, FC	Human, Mouse, Rat
	IMP3 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to IMP3.