592 Results for "

lectin

" in MedChemExpress (MCE) Product Catalog:
Products (592)

592 Results for "lectin" in MCE Product Catalog:

102
102 Publications Verification
Art. -Nr.: HY-66019
CAS. Nr.: 3326-32-7
Synonyms: Fluorescein 5-isothiocyanate
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
loading...
    loading...
13
13 Cited Publications
Art. -Nr.: HY-K0218A

MCE Streptavidin Agarose 6FF, a 6% highly cross-linked agarose reagent coupled with recombinant streptavidin, is an affinity chromatography medium for separation and purification of biotinylated peptides, antibodies, lectins, etc. The total binding capacity of Streptavidin Agarose 6FF is more than 200 nmol of D-Biotin/mL settled resin.

loading...
    loading...
7
7 Cited Publications
Art. -Nr.: HY-N7038
CAS. Nr.: 9008-97-3
Synonyms: PHA-M
Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-κB, COX2, IL-1β .
loading...
    loading...
5
5 Cited Publications
Art. -Nr.: HY-P2149
CAS. Nr.: 11028-71-0
Concanavalin A can be coupled to agarose to form Concanavalin A (agarose) (HY-P2149A). Concanavalin A (ConA) is a selective, competitive binding agent that targets specific carbohydrate structures containing glucose and mannose; it acts as a mitogen and exhibits varying degrees of cytotoxicity, hepatotoxicity, and teratogenicity. Concanavalin A is also utilized for in vivo blood glucose monitoring in the context of diabetes .
loading...
    loading...
4
4 Cited Publications
Art. -Nr.: HY-P70309
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LGALS3; MAC-2; Prev. LGALS2; MAC2; GALIG; Galactoside-Binding Protein; Epididymis Secretory Sperm Binding Protein; MAC-2 Antigen; Advanced Glycation End-Product Receptor 3; Mac-2 Antigen; lectin, Galactoside-Binding, Soluble, 3; Galectin; Carbohydrate-Bin
Species:  
Source:  
loading...
    loading...
3
3 Cited Publications
Art. -Nr.: HY-P70535
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LGALS9; Ecalectin; Galectin 9; Gal-9; LGALS9A; Urate Transporter/Channel Protein; lectin, Galactoside-Binding, Soluble, 9; Galectin; Tumor Antigen HOM-HD-21; HUAT; Galectin-9
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-131166
CAS. Nr.: 54724-00-4
Reinheit:  98.5%
Curdlan is a polysaccharide found in bacteria, consisting of a glucose homopolymer with β-1,3-glycosidic linkages . Curdlan can be recognized by Dectin-1 (a C-type lectin receptor), inducing immune responses in tissue mast cells and enhancing dendritic cell effects in tumor immunity. Curdlan holds potential for research in cancer and immune-inflammatory diseases .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-15941
CAS. Nr.: 27072-45-3
Synonyms: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-P99646
CAS. Nr.: 2418540-63-1
Synonyms: MEDI6570

Target:  

LOX-1

Gocdacimab (MEDI6570) is a fully human IgG1 monoclonal antibody inhibitor targeting the lectin-like oxidized low-density lipoprotein receptor LOX-1. By binding to LOX-1 and blocking its function, gocdacimab effectively reduces the level of free soluble LOX-1, thereby inhibiting key pathological processes such as lipid accumulation, foam cell formation, and vascular wall inflammation. Gocdacimab can interfere with atherosclerosis-related mechanisms, and it is used for research on atherosclerosis, and type 2 diabetes mellitus .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-P72637
Reinheit:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: LGALS9; Ecalectin; Galectin 9; Gal-9; LGALS9A; Urate Transporter/Channel Protein; lectin, Galactoside-Binding, Soluble, 9; Galectin; Tumor Antigen HOM-HD-21; HUAT; Galectin-9
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-P81214
Synonyms: Mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_HUMAN; Macrophage mannose receptor 1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1.

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Rat

loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P99376
CAS. Nr.: 2108782-45-0
Synonyms: OMS 721; Anti-MASP2 Reference Antibody (narsoplimab)

Target:  

SARS-CoV

Forschungsgebiete:  

Infection

Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2 .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P79127
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC11; Siglec-11; Sialic Acid Binding Ig Like lectin 11; Sialic Acid Binding Ig-Like lectin 11; Sialic Acid-Binding Ig-Like lectin 11; Sialic Acid-Binding lectin 11
Species:  
Source:  
CHO
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-W039897
CAS. Nr.: 617-04-9
Synonyms: α-Methyl-D-mannoside
Forschungsgebiete:  

Infection

Methyl α-D-mannopyranoside (α-Methyl-D-mannoside) is a methyl glycoside derivative and conformational stabilizer of α-D-mannopyranose. The glycosidic bond conformation of Methyl α-D-mannopyranoside is significantly affected by the environment. In aqueous solution, Methyl α-D-mannopyranoside stabilizes into a trans conformation via intermolecular hydrogen bonds; in the gas phase, however, steric interactions drive Methyl α-D-mannopyranoside to prefer a clockwise gauche conformation. Methyl α-D-mannopyranoside also serves as a major component of secondary cell wall polymers in some bacteria and an active precursor site for virus-targeted glycoproteins. Methyl α-D-mannopyranoside acts as an acceptor substrate for alternansucrase, mediating the transfer of D-glucopyranosyl groups to generate a variety of glycosylated oligosaccharide products, with methyl α-D-glucopyranosyl-(1→6)-α-D-mannopyranoside as the main component. Methyl α-D-mannopyranoside is applicable to studies on bacterial pathogenic mechanisms associated with mannose-specific fimbrial lectins .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P70742
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC15; Sialic Acid-Binding Ig-Like lectin 15; Prev. CD33L3; SIGLEC-15; CD33 Antigen-Like 3; Sialic Acid Binding Ig-Like lectin 15; HsT1361; Siglec-15; Sialic Acid Binding Ig Like lectin 15; CD33 Molecule-Like 3
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-NP091
Synonyms: WGA
Wheat Germ Agglutinin (WGA) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Wheat Germ Agglutinin (WGA) is a biological material or organic compound that can be used in life science research .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-NP163C
Synonyms: WGA-AF555
Wheat germ agglutinin-AF555 (WGA-AF555) is a membrane-staining lectin conjugate that combines wheat germ agglutinin with the Alexa Fluor 555 fluorescent dye. Wheat germ agglutinin-AF555 is used for precise staining and contour delineation of cell membranes. Wheat germ agglutinin-AF555 also effectively distinguishes between surface vimentin and intracellular vimentin in cells .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P75335
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC1B; C-Type lectin Domain Family 1, Member B; C-Type lectin Domain Family 1 Member B; 1810061I13Rik; CLEC2; PRO1384; CLEC-2; QDED721; C-Type lectin-Like Receptor 2
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P70101
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC7A; CDNA FLJ59887, Moderately Similar To Homo Sapiens C-Type lectin Domain Family 7, Member A (CLEC7A), Transcript Variant 4, MRNA; Prev. CLECSF12; C-Type lectin Domain Containing 7A Transcript Variant 7; C-Type lectin Domain Family 7 Member A; C-Type
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P701099
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ITLN1; Galactofuranose-Binding lectin; Intelectin 1; Endothelial lectin HL-1; ITLN; Intelectin-1; LFR; FLJ20022; Omentin; ITLN-1; HIntL; INTL; HL-1; Intelectin Variant; Intelectin 1 (Galactofuranose Binding); HL1; Intestinal Lactoferrin Receptor
Species:  
Source:  
loading...
    loading...