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Macrophage mannose receptor 1 Antibody (YA3531)

(Synonyms: Mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_HUMAN; Macrophage mannose receptor 1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1.)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Macrophage mannose receptor 1 Antibody (YA3531) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Macrophage mannose receptor 1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human, Rat

  • Formulation:

    Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3531)
  • Macrophage mannose receptor 1 Antibody (YA3531) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

Macrophage mannose receptor 1 Antibody (YA3531) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Macrophage mannose receptor 1.

  • Host Rabbit
  • Clonality Monoclonal, Recombinant
  • Species Reactivity
    Human, Rat
  • Observed Molecular Weight
    Observed band size: 166 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 166 kDa
Species Reactivity Database
Immunogen

A synthetic peptide of human Mannose Receptor.

Sensitivity

Endogenous

Purification

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3103103

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3531)
    Western blot analysis of extracts from M-lymph (lane 1) and M-lung (lane 2) using MRC1 antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.

Background

  • Function

    Macrophage mannose receptor 1 mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains; (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens; (Microbial infection) Acts as a receptor for Dengue virus envelope protein E; (Microbial infection) Interacts with Hepatitis B virus envelope protein

  • Subcellular Localization

    Endosome membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein

  • Isoforms & Post-Translational Modification

    P22897 has 2 isomers: P22897-1: 166012 Da (predicted); P22897-2: 56554 Da (predicted).

  • Subunit

    (Microbial infection) Interacts with Dengue virus

  • SwissProt ID

    P22897

  • Gene ID
    4360 [NCBI]
  • Synonyms

    Mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_HUMAN; Macrophage mannose receptor 1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1.

Macrophage mannose receptor 1 Antibody (YA3531) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Western blot analysis of extracts from M-lymph (lane 1) and M-lung (lane 2) using MRC1 antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.

  • Macrophage mannose receptor 1 Antibody (YA3531) Product Image
    1/16
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3531)
  • Macrophage mannose receptor 1 Antibody (YA3531) Product Image
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3531)
    1/1
    MedChemExpress Validation
     Western blot analysis of extracts from M-lymph (lane 1) and M-lung (lane 2) using MRC1 antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3531)
  • Macrophage mannose receptor 1 Antibody (YA3531) Product Image
    MedChemExpress Validation

    Western blot analysis of extracts from M-lymph (lane 1) and M-lung (lane 2) using MRC1 antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.

  • Macrophage mannose receptor 1 Antibody (YA3531) Product Image WB