Mannose Receptor
The mannose receptor (MRC1, CD206) is a multi-domain endocytic receptor of macrophages, dendritic cells, and lymphatic endothelium, widely used as a marker of alternatively activated (M2) macrophages. Its extracellular region contains eight C-type lectin-like domains flanked by an N-terminal cysteine-rich domain and a collagen-like segment, allowing it to bind terminal mannose, fucose, and N-acetylglucosamine on microbial surfaces as well as sulfated sugars and collagens. It continuously recycles through early endosomes, clearing lysosomal hydrolases, myeloperoxidase, and pathogen glycoconjugates, and it modulates adaptive immunity via antigen uptake. Recombinant mannose receptor supports glycan-binding studies, M2-polarization assays, and targeted drug-delivery research.
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Mannose Receptor Recombinant Proteins (6)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
