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CD206/MMR Protein, Human (HEK293, His)

Cat. No.: HY-P78736
Handling Instructions

The CD206/MMR protein acts as a multifunctional mediator in macrophages, promoting glycoprotein internalization. It has a broad binding capacity, interacting with both sulfated and non-sulfated polysaccharide chains. CD206/MMR Protein, Human (HEK293, His) is the recombinant human-derived CD206/MMR protein, expressed by HEK293 , with C-His labeled tag. The total length of CD206/MMR Protein, Human (HEK293, His) is 1371 a.a., with molecular weight of 150-190 kDa.

For research use only. We do not sell to patients.

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Description

The CD206/MMR protein acts as a multifunctional mediator in macrophages, promoting glycoprotein internalization. It has a broad binding capacity, interacting with both sulfated and non-sulfated polysaccharide chains. CD206/MMR Protein, Human (HEK293, His) is the recombinant human-derived CD206/MMR protein, expressed by HEK293 , with C-His labeled tag. The total length of CD206/MMR Protein, Human (HEK293, His) is 1371 a.a., with molecular weight of 150-190 kDa.

Background

CD206/MMR Protein plays a pivotal role in cellular processes, acting as a versatile mediator of endocytosis in macrophages, specifically facilitating the internalization of glycoproteins. The protein exhibits a broad binding capacity, interacting with both sulfated and non-sulfated polysaccharide chains. In the context of microbial infection, CD206/MMR further assumes a critical role as a phagocytic receptor, contributing to the recognition and engulfment of bacteria, fungi, and other pathogens. This multifaceted functionality underscores CD206/MMR's significance in orchestrating the cellular response to glycoproteins and microbial challenges, showcasing its role as a key player in innate immunity and cellular homeostasis.

Species

Human

Source

HEK293

Tag

C-His

Accession

P22897-1 (L19-A1389)

Gene ID
Molecular Construction
N-term
CD206 (L19-A1389)
Accession # P22897-1
His
C-term
Synonyms
MMR; CD206; hMR; MRC1; CLEC13D; CLEC13DL; MRC1L1
Molecular Weight

160-180 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CD206/MMR Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CD206/MMR Protein, Human (HEK293, His)
Cat. No.:
HY-P78736
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