54724-00-4
54724-00-4
Chemical Structure
Curdlan
- No. CAS: 54724-00-4
- Formula:(C6H10O5)n
- Molecular Weight:N/A
SMILES: OC[C@H]1O[C@@H](C)[C@H](O)C(OC)[C@@H]1O.[n]
Biological Activity: Curdlan is a polysaccharide found in bacteria, consisting of a glucose homopolymer with β-1,3-glycosidic linkages[1]. Curdlan can be recognized by Dectin-1 (a C-type lectin receptor), inducing immune responses in tissue mast cells and enhancing dendritic cell effects in tumor immunity. Curdlan holds potential for research in cancer and immune-inflammatory diseases[1][2][3].
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Curdlan | 98.01% | Curdlan is a polysaccharide found in bacteria, consisting of a glucose homopolymer with β-1,3-glycosidic linkages. Curdlan can be recognized by Dectin-1 (a C-type lectin receptor), inducing immune responses in tissue mast cells and enhancing dendritic cell effects in tumor immunity. Curdlan holds potential for research in cancer and immune-inflammatory diseases. | ||||||||||||||||||||
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References
- [1]. Masanori Miwa, et al. Food Applications of Curdlan. Food Hydrocolloids pp 119-124.
- [2]. Kim HS, et al. Curdlan activates dendritic cells through dectin-1 and toll-like receptor 4 signaling. Int Immunopharmacol. 2016 Oct;39:71-78. [Content Brief]
- [3]. Żelechowska P, et al. Curdlan stimulates tissue mast cells to synthesize pro-inflammatory mediators, generate ROS, and migrate via Dectin-1 receptor. Cell Immunol. 2020 May;351:104079. [Content Brief]
