Search Result

Results for "

lectin domain

" in MedChemExpress (MCE) Product Catalog:

By Targets:	C-type Lectin-like Receptors (CTLRs) (2) ADC Payload (1) Bacterial (1) Biochemical Assay Reagents (1) Calcium Channel (1) Complement System (1) E-Selectin (1) Ser/Thr Protease (1) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Endocrinology (1) Inflammation/Immunology (5)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Targets Recommended: C-type Lectin-like Receptors (CTLRs) Discoidin Domain Receptor Epigenetic Reader Domain LOX-1 EHD Protein WDR5 YTHDF PASK/STK37 VISTA SHP1 PIKfyve BCL6 PNPLA3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-126666

PNU-159682 carboxylic acid	ADC Payload	Inflammation/Immunology Cancer
PNU-159682 carboxylic acid (Compound 53) is a potent ADCs cytotoxin and encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. PNU-159682 carboxylic acid has protein fold and diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response .

HY-P3752

Gly-Ala-Tyr H-Gly-Ala-Tyr-OH	Biochemical Assay Reagents Bacterial	Others
Gly-Ala-Tyr (H-Gly-Ala-Tyr-OH) is a tripeptide substrate composed of L-glycine, alanine, and L-tyrosine joined in sequence by peptide linkages. Gly-Ala-Tyr can be hydrolyzed at both extracellular and intracellular levels by Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus, Lactobacillus acidophilus, and Bifidobacterium spp. Ala-Gly-Tyr is functionally related to L-alanine, glycine and L-tyrosine. .

HY-P990025

Empasiprubart ARGX-117	Complement System	Inflammation/Immunology
Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .

HY-125475

Rivipansel GMI-1070	E-Selectin	Cardiovascular Disease
Rivipansel is a small-molecule glycomimetic pan-selectin antagonist with inhibitory activity against E-selectin and P-selectin. Rivipansel binds tightly to the lectin domain of E-selectin, and selectively blocks the recognition of CD62L by E-selectin without affecting the binding of PSGL-1 to E-selectin. Rivipansel functionally inhibits the adhesion of hematopoietic cells to endothelial cells, and is applicable to research related to sickle cell disease .

HY-P990258

Anti-Mouse CLEC9A/CD370 Antibody (7H11)	Transmembrane Glycoprotein C-type Lectin-like Receptors (CTLRs)	Inflammation/Immunology Cancer
Anti-Mouse CLEC9A/CD370 Antibody (7H11) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CLEC9A/CD370. Anti-Mouse CLEC9A/CD370 Antibody (7H11) reacts with mouse CLEC9A (C-type lectin domain family member 9A) and blocks CLEC9A. Anti-Mouse CLEC9A/CD370 Antibody (7H11) can be used for the researches of cancer and immunology, such as B16.F10-OVA tumor .

HY-P991818

Anti-Mouse CD370 Antibody (1F6)	C-type Lectin-like Receptors (CTLRs)	Inflammation/Immunology
Anti-Mouse CD370 Antibody (1F6) reacts with the mouse CD370 (also known as CLEC9A or DNGR1). CD370 is a type II membrane protein with a single extracellular C-type lectin domain. Recommend Isotype Controls: Rat IgG1 kappa, Isotype Control (HY-P99979) .

HY-W069974

Ca2+ -Langerin-IN-1	Calcium Channel	Inflammation/Immunology
Ca2+-Langerin-IN-1 (Compound 3) is a allosteric Langerin inhibitor. Langerin is a C-type lectin that is expressed on Langerhans cells and plays a crucial role in pathogen recognition and innate immune activation. The K_D value of the CRD domain of murine Langerin protein for Ca2+-Langerin-IN-1 is 17 μM under the presence of Ca²⁺ and 53 μM under the absence of Ca²⁺ competition. Ca2+-Langerin-IN-1 induces conformational changes and competitively replaces Ca²⁺, thereby inhibiting the carbohydrate recognition function of the protein. Ca2+-Langerin-IN-1 can be used in the research of immunomodulatory therapy .

HY-P992463

SHR-2010	Ser/Thr Protease	Endocrinology
SHR-2010 is a fully humanized monoclonal antibody targeting MASP-2. SHR-2010 selectively inhibits lectin pathway activation without affecting classical or alternative complement pathways. SHR-2010 can be used for the research of IgA nephropathy .

Cat. No.	Product Name	Target	Research Area

HY-P3752

Gly-Ala-Tyr H-Gly-Ala-Tyr-OH	Biochemical Assay Reagents Bacterial	Others
Gly-Ala-Tyr (H-Gly-Ala-Tyr-OH) is a tripeptide substrate composed of L-glycine, alanine, and L-tyrosine joined in sequence by peptide linkages. Gly-Ala-Tyr can be hydrolyzed at both extracellular and intracellular levels by Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus, Lactobacillus acidophilus, and Bifidobacterium spp. Ala-Gly-Tyr is functionally related to L-alanine, glycine and L-tyrosine. .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990025

Empasiprubart ARGX-117	Complement System	Inflammation/Immunology
Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .

HY-P990258

Anti-Mouse CLEC9A/CD370 Antibody (7H11)	Transmembrane Glycoprotein C-type Lectin-like Receptors (CTLRs)	Inflammation/Immunology Cancer
Anti-Mouse CLEC9A/CD370 Antibody (7H11) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CLEC9A/CD370. Anti-Mouse CLEC9A/CD370 Antibody (7H11) reacts with mouse CLEC9A (C-type lectin domain family member 9A) and blocks CLEC9A. Anti-Mouse CLEC9A/CD370 Antibody (7H11) can be used for the researches of cancer and immunology, such as B16.F10-OVA tumor .

HY-P991818

Anti-Mouse CD370 Antibody (1F6)	C-type Lectin-like Receptors (CTLRs)	Inflammation/Immunology
Anti-Mouse CD370 Antibody (1F6) reacts with the mouse CD370 (also known as CLEC9A or DNGR1). CD370 is a type II membrane protein with a single extracellular C-type lectin domain. Recommend Isotype Controls: Rat IgG1 kappa, Isotype Control (HY-P99979) .

HY-P992463

SHR-2010	Ser/Thr Protease	Endocrinology
SHR-2010 is a fully humanized monoclonal antibody targeting MASP-2. SHR-2010 selectively inhibits lectin pathway activation without affecting classical or alternative complement pathways. SHR-2010 can be used for the research of IgA nephropathy .

Species:	Human (31) Rhesus Macaque (5) Mouse (21) Rat (11)
Tag:	SUMO (3) His (36) Tag Free (2) Avi (3) Myc (2) Flag (1) Fc (29)
Source:	HEK293 (63) Sf9 insect cells (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P78965

	CLEC17A Protein, Human (HEK293, hFc) C-Type lectin domain Containing 17A; C-Type lectin domain Family 17, Member A; Prolectin; C-Type lectin domain Family 17 Member A; FLJ45910	Human	HEK293
	CLEC17A Protein, a cell surface receptor, engages in carbohydrate-mediated intercellular communication in the germinal center. It shows affinity for glycans with alpha-linked mannose or fucose residues. As an oligomer formed through disulfide linkages, CLEC17A is crucial for complex molecular interactions, contributing to essential cellular processes within the germinal center. CLEC17A Protein, Human (CHO, hFc) is the recombinant human-derived CLEC17A protein, expressed by CHO , with N-hFc labeled tag.

HY-P7819

	Langerin/CD207 Protein, Human (HEK293, His) rHuC-type lectin domain family 4 member K/CD207, His; CD207 antigen; langerin; CD207; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K	Human	HEK293
	CLC4K protein, a calcium-dependent lectin, promotes antigen uptake. CLC4K is able to bind to sulfated as well as mannosylated glycans, keratan sulfate (KS), and β-glucan. Langerin/CD207 Protein, Human (HEK293, His) is the recombinant human-derived Langerin/CD207 protein, expressed by HEK293 , with N-6*His labeled tag.

HY-P76268

	CLEC4F/CLECSF13 Protein, Rat (HEK293) C-type lectin domain family 4 member F; C-type lectin 13; Clecsf13; Kclr	Rat	HEK293
	The CLEC4F/CLECSF13 protein, a galactose and fucose-binding receptor, indicates a role in endocytosis, pointing to its likely involvement in internalizing various cellular components and contributing to vital cellular processes. CLEC4F/CLECSF13 Protein, Rat (HEK293) is the recombinant rat-derived CLEC4F/CLECSF13 protein, expressed by HEK293 , with tag free.

HY-P70118

	CLEC4E Protein, Human (HEK293, His) rHuC-Type lectin domain Family 4 Member E/CLEC4E, His; C-Type lectin domain Family 4 Member E; C-Type lectin Superfamily Member 9; Macrophage-Inducible C-Type lectin; CLEC4E; CLECSF9; MINCLE	Human	HEK293
	The CLEC4E protein is a calcium-dependent lectin that functions as a pattern recognition receptor in the immune system.It detects and binds DAMPs and PAMPs, including α-mannose residues on mycobacterial TDM and fungi.CLEC4E Protein, Human (HEK293, His) is the recombinant human-derived CLEC4E protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P75677

	CLEC4F/CLECSF13 Protein, Mouse (HEK293, Fc) C-type lectin domain family 4 member F; C-type lectin 13; Kupffer cell receptor; Kclr	Mouse	HEK293
	CLEC4F/CLECSF13 protein, a receptor with a distinct affinity for galactose and fucose, suggests involvement in endocytosis. With a binding preference for these carbohydrates, it plays a role in recognizing and potentially internalizing cellular components. CLEC4F/CLECSF13's implication in endocytosis highlights its significance in cellular uptake mechanisms, hinting at potential contributions to various physiological processes. CLEC4F/CLECSF13 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC4F/CLECSF13 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P76832

	CLEC3A Protein, Mouse (sf9, His) C-type lectin domain family 3 member A; Cartilage-derived C-type lectin; Clecsf1; Gm796	Mouse	Sf9 insect cells
	CLEC3A protein plays a key role in promoting cell adhesion to laminin and fibronectin, indicating its crucial function in mediating cellular interactions with the extracellular matrix. This ability underscores its importance in regulating cell attachment, spreading, and signaling behaviors, contributing to the intricate network of molecular interactions governing cell-matrix interactions. CLEC3A Protein, Mouse (sf9, His) is the recombinant mouse-derived CLEC3A protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P76831

	OCIL/CLEC2D Protein, Rat (HEK293, Fc) C-type lectin domain family 2 member D5; Osteoclast inhibitory lectin; Ocil; Clec2d5	Rat	HEK293
	The OCIL/CLEC2D protein, also known as osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor located on the cell surface. Lectins are proteins that specifically bind to carbohydrates, and OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes by acting as a lectin-type receptor. OCIL/CLEC2D Protein, Rat (HEK293, Fc) is the recombinant rat-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P704629

	Clec2f Protein, Mouse (HEK293, Fc) C-type lectin domain family 2 member F; Clec2f; C-type lectin-related protein C (Clr-c); Clrc	Mouse	HEK293
	Clec2f Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Clec2f protein, expressed by HEK293, with C-hFc tag.

HY-P705501

	CLC2H Protein, Mouse (HEK293, Fc) C-type lectin domain family 2 member H; Clec2h; C-type lectin-related protein F (Clr-f); Clrf	Mouse	HEK293

HY-P77901

	OCIL/CLEC2D Protein, Human (HEK293, Fc-Avi) C-type lectin domain family 2 member D; lectin-like NK cell receptor; lectin-like transcript 1; LLT-1; CLAX; LLT1; OCIL; CLEC2D	Human	HEK293
	The OCIL/CLEC2D protein acts as a receptor for KLRB1 and protects target cells from natural killer cell-mediated lysis. It not only inhibits osteoclast formation and bone resorption, but also regulates the release of interferon-γ, indicating that it has immune and bone-related regulatory functions. OCIL/CLEC2D Protein, Human (HEK293, Fc-Avi) is the recombinant human-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc, N-Avi labeled tag.

HY-P71607

	KLRG1 Protein, Human (His-SUMO) 2F1 Ag; 2F1; C type lectin domain family 15 member A; C-type lectin domain family 15 member A; CLEC15A; KLRG 1; KLRG1; KLRG1 protein	Human	E. coli
	KLRG1 Protein exerts inhibitory effects on NK cells and T-cells by binding to their non-MHC ligands, potentially recognizing "missing self" through conserved sites on classical cadherins like E-cadherin/CDH1, N-cadherin/CDH2, and R-cadherin/CDH4. Existing as a monomer and homodimer connected by disulfide bonds, KLRG1 interacts with PTPN11 and INPP5D via its ITIM motif, suggesting involvement in signal transduction pathways. KLRG1 Protein, Human (His-SUMO) is the recombinant human-derived KLRG1 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P704736

	KLRG1 Protein, Human (HEK293, His) 2F1 Ag; 2F1; C type lectin domain family 15 member A; C-type lectin domain family 15 member A; CLEC15A; KLRG 1; KLRG1; KLRG1 protein	Human	HEK293
	KLRG1 Protein exerts inhibitory effects on NK cells and T-cells by binding to their non-MHC ligands, potentially recognizing "missing self" through conserved sites on classical cadherins like E-cadherin/CDH1, N-cadherin/CDH2, and R-cadherin/CDH4. Existing as a monomer and homodimer connected by disulfide bonds, KLRG1 interacts with PTPN11 and INPP5D via its ITIM motif, suggesting involvement in signal transduction pathways. KLRG1 Protein, Human (HEK293, His) is the recombinant human-derived KLRG1 protein, expressed by HEK293, with N-His labeled tag.

HY-P703697

	CLEC11A/SCGF-alpha Protein, Rat (HEK293, His) C-type lectin domain family 11 member A; Lymphocyte secreted C-type lectin; Osteolectin; Stem cell growth factor; Clec11a	Rat	HEK293
	CLEC11A/SCGF-alpha Protein, Rat (HEK293, His) is the recombinant rat-derived CLEC11A/SCGF-alpha protein, expressed by HEK293, with C-His tag.

HY-P705500

	CLC2E Protein, Mouse (HEK293, Fc) C-type lectin domain family 2 member E; Clec2e; C-type lectin-related protein A (Clr-a); Clec2e; Clra	Mouse	HEK293

HY-P76270

	CLEC9A Protein, Mouse (HEK293, Fc) C-type lectin domain family 9 member A; CD370; Dngr-1	Mouse	HEK293
	The CLEC9A protein is uniquely expressed on specific myeloid cells and acts as an endocytic receptor responsible for the uptake and processing of materials from dead cells. CLEC9A recognizes filamentous actin, especially in damaged cell membranes, and plays a critical role in Syk-dependent cross-presentation of dead cell antigens. CLEC9A Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC9A protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P77437

	Langerin/CD207 Protein, Rhesus Macaque (HEK293, Fc) C-type lectin domain family 4 member K; CLEC4K	Rhesus Macaque	HEK293
	Langerin, also known as CD207, is a calcium-dependent lectin with mannose-binding specificity. Notably, it induces the formation of Birbeck granules (BG) and acts as an effective regulator of membrane stacking and zipping. Langerin/CD207 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived Langerin/CD207 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P77336A

	CLEC4E Protein, Rhesus Macaque (HEK293, hFc) C-Type lectin domain Family 4 Member E; CLECSF9; MINCLE	Rhesus Macaque	HEK293
	CLEC4E Protein is a calcium-dependent lectin displaying mannose-binding specificity, and induces the formation of Birbeck granules (BGs). CLEC4E Protein is a potent regulator of membrane superimposition and zippering, and binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. CLEC4E Protein, Rhesus Macaque (HEK293, hFc) is the recombinant rhesus macaque-derived CLEC4E, expressed by HEK293, with N-hFc labeled tag.

HY-P75339

	CLEC-1/CLEC1A Protein, Mouse (HEK293, hFc) C-type lectin domain family 1 member A; CLEC1A	Mouse	HEK293
	CLEC-1/CLEC1A proteins belong to the CTL/CTLD superfamily and are known for their diverse functions in cell adhesion, signaling, glycoprotein turnover, inflammation, and immune responses. It is involved in potentially regulating dendritic cell function. CLEC-1/CLEC1A Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived CLEC-1/CLEC1A protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P76830

	CLEC2B Protein, Human (HEK293, Fc) C-type lectin domain family 2 member B; AICL; CLECSF2; IFNRG1	Human	HEK293
	CLEC2B Protein, Human (HEK293, Fc) is the recombinant human-derived CLEC2B protein, expressed by HEK293, with N-hFc labeled tag.

HY-P77336

	CLEC4E Protein, Rhesus Macaque (HEK293, hFc, solution) C-Type lectin domain Family 4 Member E; CLECSF9; MINCLE	Rhesus Macaque	HEK293
	CLEC4E Protein is a calcium-dependent lectin displaying mannose-binding specificity, and induces the formation of Birbeck granules (BGs). CLEC4E Protein is a potent regulator of membrane superimposition and zippering, and binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. CLEC4E Protein, Rhesus Macaque (HEK293, hFc, solution) is the recombinant Rhesus Macaque-derived CLEC4E protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P78931

	ASGR1/ASGPR1 Protein, Human (Biotinylated, HEK293, His-Avi) ASGP-R 1; ASGPR 1; C-type lectin domain family 4 member H1; Hepatic lectin H1; HL-1	Human	HEK293
	ASGR1/ASGPR1 mediates endocytosis of desialylated glycoproteins, recognizing galactose and N-acetylgalactosamine units. Ligand binding leads to internalization and sorting organelle transport, followed by receptor return to the cell membrane. ASGR1/ASGPR1 interacts with LASS2. ASGR1/ASGPR1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived ASGR1/ASGPR1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P76269

	CLEC5A/MDL-1 Protein, Rat (HEK293, His) C-type lectin domain family 5 member A; MDL-1; CLECSF5	Rat	HEK293
	The CLEC5A/MDL-1 protein positively regulates osteoclastogenesis and regulates inflammatory responses. It acts as a critical macrophage receptor for dengue virus serotypes 1-4, triggering signaling through TYROBP phosphorylation. This interaction stimulates the release of pro-inflammatory cytokines without viral entry. CLEC5A/MDL-1 Protein, Rat (HEK293, His) is the recombinant rat-derived CLEC5A/MDL-1 protein, expressed by HEK293 , with N-His labeled tag.

HY-P76828

	CLEC14A Protein, Mouse (HEK293, His) C-type lectin domain family 14 member A; EGFR-5; C14orf27	Mouse	HEK293
	CLEC14A Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC14A protein, expressed by HEK293, with C-His labeled tag.

HY-P76829

	CLEC14A Protein, Rat (HEK293, Fc) C-type lectin domain family 14 member A; EGFR-5; C14orf27	Rat	HEK293
	CLEC14A Protein, Rat (HEK293, Fc) is the recombinant rat-derived CLEC14A protein, expressed by HEK293, with C-hFc labeled tag.

HY-P70101

	Dectin-1/CLEC7A Protein, Human (HEK293, Fc) 1 Publications Verification rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; DECTIN1CANDF4	Human	HEK293
	The Dectin-1/CLEC7A protein is a lectin and pattern recognition receptor that targets β-1,3- and β-1,6-linked glucans in bacterial and fungal cell walls. It triggers Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting splenic tyrosine kinase (SYK) and activating the CARD domain-BCL10-MALT1 (CBM) signalosome. Dectin-1/CLEC7A Protein, Human (HEK293, Fc) is the recombinant human-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P704035

	Dectin-1/CLEC7A Protein, Human (HEK293) rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; DECTIN1CANDF4	Human	HEK293
	The Dectin-1/CLEC7A protein is a lectin and pattern recognition receptor that targets β-1,3- and β-1,6-linked glucans in bacterial and fungal cell walls. It triggers Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting splenic tyrosine kinase (SYK) and activating the CARD domain-BCL10-MALT1 (CBM) signalosome. Dectin-1/CLEC7A Protein, Human (HEK293) is the recombinant human-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with no tag.

HY-P704036

	Dectin-1/CLEC7A Protein, Human (HEK293, hFc) rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; DECTIN1CANDF4	Human	HEK293
	The Dectin-1/CLEC7A protein is a lectin and pattern recognition receptor that targets β-1,3- and β-1,6-linked glucans in bacterial and fungal cell walls. It triggers Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting splenic tyrosine kinase (SYK) and activating the CARD domain-BCL10-MALT1 (CBM) signalosome. Dectin-1/CLEC7A Protein, Human (HEK293, hFc) is the recombinant human-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with hFc tag.

HY-P71180

	LOX-1/OLR1 Protein, Human (HEK293, His) Oxidized Low-Density Lipoprotein Receptor 1; Ox-LDL Receptor 1; C-Type lectin domain Family 8 Member A; lectin-Like Oxidized LDL Receptor 1; LOX-1; lectin-Like oxLDL Receptor 1; hLOX-1; lectin-Type Oxidized LDL Receptor 1; OLR1; CLEC8A; LOX1	Human	HEK293
	The OLR1 protein is a receptor on vascular endothelial cells that plays a key role in the recognition, internalization, and degradation of oxidatively modified low-density lipoprotein (oxLDL). As a marker of atherosclerosis, oxLDL induces activation of vascular endothelial cells, leading to proinflammatory responses, oxidative conditions, and apoptosis. OLR1 Protein, Human (HEK293, His) is the recombinant human-derived OLR1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71602

	Langerin/CD207 Protein, Mouse (His) Cd207; Clec4kC-type lectin domain family 4 member K; Langerin; CD antigen CD207	Mouse	E. coli
	Langerin, also known as CD207, is a calcium-dependent lectin with mannose-binding specificity. Notably, it induces the formation of Birbeck granules (BG) and acts as an effective regulator of membrane stacking and zipping. Langerin/CD207 Protein, Mouse (His) is the recombinant mouse-derived Langerin/CD207 protein, expressed by E. coli , with N-His labeled tag.

HY-P75335

	CLEC1B/CLEC-2 Protein, Mouse (HEK293, Fc) C-type lectin domain family 1 member B; CLEC1B; CLEC2	Mouse	HEK293
	The CLEC1B/CLEC-2 protein serves as a platelet receptor for PDPN. When activated, it signals through SRC and SYK kinases, activating PLCG2. CLEC1B forms homodimers and interacts with RACK1, promoting its ubiquitination and degradation. It also interacts with SYK and PDPN, independently of glycosylation, activating CLEC1B/CLEC-2. CLEC1B/CLEC-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC1B/CLEC-2 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P75337

	CLEC-1/CLEC1A Protein, Rat (HEK293, Fc) CLEC1A; C-type lectin domain family 1 member A; CLEC1	Rat	HEK293
	CLEC-1/CLEC1A proteins belong to the CTL/CTLD superfamily and are known for their diverse functions in cell adhesion, signaling, glycoprotein turnover, inflammation, and immune responses. It is involved in potentially regulating dendritic cell function. CLEC-1/CLEC1A Protein, Rat (HEK293, Fc) is the recombinant rat-derived CLEC-1/CLEC1A protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P75338

	CLEC-1/CLEC1A Protein, Human (HEK293, Fc) CLEC1A; C-type lectin domain family 1 member A; CLEC1	Human	HEK293
	CLEC-1/CLEC1A proteins belong to the CTL/CTLD superfamily and are known for their diverse functions in cell adhesion, signaling, glycoprotein turnover, inflammation, and immune responses. It is involved in potentially regulating dendritic cell function. CLEC-1/CLEC1A Protein, Human (HEK293, Fc) is the recombinant human-derived CLEC-1/CLEC1A protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P77337

	CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, His) C-type lectin domain family 5 member A; MDL-1; CLECSF5	Rhesus Macaque	HEK293
	CLEC5A Protein is a cell surface receptor that signals via TYROBP, and functions as a positive regulator of osteoclastogenesis. CLEC5A Protein regulates inflammatory responses. CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CLEC5A/MDL-1 protein, expressed by HEK293 , with N-His labeled tag.

HY-P75336A

	CLEC1B/CLEC-2 Protein, Human (HEK293, His) C-type lectin domain family 1 member B; CLEC1B; CLEC2	Human	HEK293
	CLEC1B/CLEC-2 protein is a C-type lectin-like receptor that acts as a platelet receptor and snake venom protein receptor for PDPN in microbial infections. Upon activation, it initiates a signaling cascade involving SRC and SYK kinases, leading to PLCG2 activation. CLEC1B/CLEC-2 Protein, Human (HEK293, His) is the recombinant human-derived CLEC1B/CLEC-2, expressed by HEK293, with N-10*His labeled tag.

HY-P77338

	CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, Fc) C-type lectin domain family 5 member A; MDL-1; CLECSF5	Rhesus Macaque	HEK293
	CLEC5A Protein is a cell surface receptor that signals via TYROBP, and functions as a positive regulator of osteoclastogenesis. CLEC5A Protein regulates inflammatory responses. CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CLEC5A/MDL-1 protein, expressed by HEK293 , with N-mFc labeled tag.

HY-P72014

	CLEC4C Protein, Human (His-SUMO) CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150C-type lectin domain family 4 member C; Blood dendritic cell antigen 2; BDCA-2; C-type lectin superfamily member 7; Dendritic lectin; CD antigen CD303	Human	E. coli
	CLEC4C is a lectin-type cell surface receptor that plays a crucial role in antigen capture by dendritic cells. It specifically recognizes non-sialylated galactose-terminated biantennary glycans with the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. CLEC4C Protein, Human (His-SUMO) is the recombinant human-derived CLEC4C protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P76267

	CLEC12A/MICL Protein, Human (HEK293, His) C-type lectin domain family 12 member A; CLL-1; DCAL-2; MICL; CD371	Human	HEK293
	CLEC12A/MICL (C-type lectin domain family 12 member A/myelosuppressive C-type lectin-like receptor) is a cell surface receptor that acts as a modulator of signaling cascades, specifically promoting target MAP kinases Protease. CLEC12A/MICL Protein, Human (HEK293, His) is the recombinant human-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag.

HY-P76671

	Tetranectin/CLEC3B Protein, Mouse (HEK293, His) TN; C-Type lectin domain Family 3 Member B; Plasminogen Kringle 4-Binding Protein; TNA	Mouse	HEK293
	Tetranectin/CLEC3B protein exhibits binding to plasminogen and isolated kringle 4, suggesting potential roles in exocytosis-related molecule packaging and ocular physiology.Its homotrimeric structure emphasizes a propensity for trimeric complexes, highlighting the multifaceted nature of Tetranectin/CLEC3B in diverse molecular interactions and cellular processes.Tetranectin/CLEC3B Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tetranectin/CLEC3B protein, expressed by HEK293 , with C-His labeled tag.

HY-P76836

	CLEC4D Protein, Rat (HEK293, His) C-type lectin domain family 4 member D; CLEC-6; Dectin-3; CD368; CLECSF8	Rat	HEK293
	CLEC4D, a calcium-dependent lectin, detects DAMPs and PAMPs from bacteria and fungi. It interacts with FCER1G in myeloid cells, forming a functional complex that activates signaling pathways and promotes antigen-presenting cell maturation and T-cell priming. CLEC4D also combats fungal infections and contributes to antigen uptake for clearance or presentation to T-cells. Its interaction with CLEC4E strengthens the interaction with FCER1G. CLEC4D Protein, Rat (HEK293, His) is the recombinant rat-derived CLEC4D protein, expressed by HEK293 , with N-His labeled tag.

HY-P75336

	CLEC1B/CLEC-2 Protein, Human (HEK293, His, solution) C-type lectin domain family 1 member B; CLEC1B; CLEC2	Human	HEK293
	CLEC1B/CLEC-2 protein is a C-type lectin-like receptor that acts as a platelet receptor and snake venom protein receptor for PDPN in microbial infections. Upon activation, it initiates a signaling cascade involving SRC and SYK kinases, leading to PLCG2 activation. CLEC1B/CLEC-2 Protein, Human (HEK293, His, solution) is the recombinant human-derived CLEC1B/CLEC-2 protein, expressed by HEK293 , with N-His labeled tag.

HY-P76834

	CLEC4D Protein, Human (HEK293, His) C-type lectin domain family 4 member D; CLEC-6; Dectin-3; CD368; CLECSF8	Human	HEK293
	The CLEC4D protein is a calcium-dependent lectin that functions as a pattern recognition receptor in the innate immune system, recognizing DAMPs and PAMPs on bacteria and fungi. It forms a functional complex with FCER1G in myeloid cells, triggering immune activation. CLEC4D Protein, Human (HEK293, His) is the recombinant human-derived CLEC4D protein, expressed by HEK293 , with N-His labeled tag.

HY-P76835

	CLEC4D Protein, Rat (HEK293, Fc) C-type lectin domain family 4 member D; CLEC-6; Dectin-3; CD368; CLECSF8	Rat	HEK293
	CLEC4D, a calcium-dependent lectin, detects DAMPs and PAMPs from bacteria and fungi. It interacts with FCER1G in myeloid cells, forming a functional complex that activates signaling pathways and promotes antigen-presenting cell maturation and T-cell priming. CLEC4D also combats fungal infections and contributes to antigen uptake for clearance or presentation to T-cells. Its interaction with CLEC4E strengthens the interaction with FCER1G. CLEC4D Protein, Rat (HEK293, Fc) is the recombinant rat-derived CLEC4D protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P71679

	CLEC4C Protein, Human (HEK293, His, Myc) CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150C-type lectin domain family 4 member C; Blood dendritic cell antigen 2; BDCA-2; C-type lectin superfamily member 7; Dendritic lectin; CD antigen CD303	Human	HEK293
	CLEC4C is a lectin-type cell surface receptor that plays a crucial role in antigen capture by dendritic cells. It specifically recognizes non-sialylated galactose-terminated biantennary glycans with the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. CLEC4C Protein, Human (HEK293, His, Myc) is the recombinant human-derived CLEC4C protein, expressed by HEK293 , with N-6*His, N-Myc labeled tag.

HY-P704542

	CLEC4C Protein, Human (HEK293, Fc) CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150C-type lectin domain family 4 member C; Blood dendritic cell antigen 2; BDCA-2; C-type lectin superfamily member 7; Dendritic lectin; CD antigen CD303	Human	HEK293
	CLEC4C is a lectin-type cell surface receptor that plays a crucial role in antigen capture by dendritic cells. It specifically recognizes non-sialylated galactose-terminated biantennary glycans with the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. CLEC4C Protein, Human (HEK293, Fc) is the recombinant human-derived CLEC4C protein, expressed by HEK293, with N-hFc labeled tag.

HY-P705469

	CLEC4C Protein, Human (HEK293, His) CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150C-type lectin domain family 4 member C; Blood dendritic cell antigen 2; BDCA-2; C-type lectin superfamily member 7; Dendritic lectin; CD antigen CD303	Human	HEK293

HY-P75296A

	Dectin-1/CLEC7A Protein, Mouse (HEK293, His) C-type lectin domain family 7 member A; Clecsf12; CD369; Clec7a	Mouse	HEK293
	Dectin-1/CLEC7A acts as a lectin and specifically recognizes β-1,3-linked and β-1,6-linked glucans in bacterial and fungal cell walls. Dectin-1/CLEC7A is critical for Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting SYK through its immunoreceptor tyrosine-based activation motif (ITAM), thereby activating NF-kappa-B. Dectin-1/CLEC7A Protein, Mouse (HEK293, His) is the recombinant mouse-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-His labeled tag.

HY-P71636

	CD367/CLEC4A Protein, Mouse (Myc, His-SUMO) Clec4a; Clec4a2; Clecsf6; DcirC-type lectin domain family 4 member A; C-type lectin superfamily member 6; Dendritic cell immunoreceptor; CD antigen CD367	Mouse	E. coli
	CD367/CLEC4A protein may regulate immune responses and affect dendritic cell (DC) differentiation.As a C-type lectin receptor, it binds carbohydrates and interacts weakly with N-acetylglucosamine.CD367/CLEC4A Protein, Mouse (Myc, His-SUMO) is the recombinant mouse-derived CD367/CLEC4A protein, expressed by E.coli , with N-His, C-Myc, N-SUMO labeled tag.

HY-P75296

	Dectin-1/CLEC7A Protein, Mouse (HEK293, His, solution) C-type lectin domain family 7 member A; Clecsf12; CD369; Clec7a	Mouse	HEK293
	Dectin-1/CLEC7A protein has (1->3)-β-D-glucan binding and pattern recognition receptor activity, participates in immune responses and recognizes specific structures. It regulates cytokine production and responds to fungal pathogens while being active on the cell surface. Dectin-1/CLEC7A Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-His labeled tag.

HY-P75638

	CD302/CLEC13A Protein, Mouse (HEK293, His) CD302 antigen; C-type lectin domain family 13 member A; CD302; CLEC13A	Mouse	HEK293
	CD302/CLEC13A Protein, a potential multifunctional C-type lectin receptor, may engage in endocytosis, phagocytosis, cell adhesion, and migration processes. CD302/CLEC13A Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD302/CLEC13A protein, expressed by HEK293 , with C-His labeled tag.

HY-P76796

	CD302/CLEC13A Protein, Rat (HEK293, His) CD302 antigen; C-type lectin domain family 13 member A; CD302; CLEC13A	Rat	HEK293
	The CD302/CLEC13A protein emerged as a potential multifunctional C-type lectin receptor, indicating its widespread involvement in cellular processes. This protein has a potential role in endocytosis and phagocytosis and is involved in cellular clearance. CD302/CLEC13A Protein, Rat (HEK293, His) is the recombinant rat-derived CD302/CLEC13A protein, expressed by HEK293 , with C-His labeled tag.

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Host:	Mouse (5) Rabbit (7)
Reactivity:	Human (12) Mouse (2) Rat (4)
Application:	IHC-P (3) ICC/IF (1) IP (1) WB (6) FC (2) ELISA (5)
Isotype:	IgG (6) IgG1 (1) IgG,IgG/Kappa (1)
Conjugation:	Non-conjugated (13) Biotin (2)
Clonality:	Monoclonal (10) Recombinant (4)
Modification:	Unmodified (11)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87390

	CLEC4F Antibody (YA7073) C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 13 antibody; C-type lectin 13 antibody; C-type lectin domain family 4 member F antibody; C-type lectin superfamily member 13 antibody; CLC4F_HUMAN antibody; Clec4f antibody; CLECSF13 antibody; KCLR antibody	WB, FC	Human
	CLEC4F Antibody (YA7073) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLEC4F.

HY-P810384

	KLRG1 Antibody (YA9701) 2F1 Ag, 2F1, C type lectin domain family 15 member A, C-type lectin domain family 15 member A, CLEC15A, ITIM containing receptor MAFA L, ITIM-containing receptor MAFA-L, Killer cell lectin like receptor G1, Killer cell lectin like receptor subfamily G member 1, Killer cell lectin-like receptor subfamily G member 1	WB	Human, Rat, Mouse
	KLRG1 Antibody (YA9701) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to KLRG1.

HY-P81429

	CLEC4C Antibody (YA1174) CLEC4C; BDCA2, CLECSF11, CLECSF7, DLEC, HECL; UNQ9361/PRO34150; C-type lectin domain family 4 member C; CD303; Blood dendritic cell antigen 2 (BDCA-2); C-type lectin superfamily member 7; Dendritic lectin	IHC-P	Human
	CLEC4C Antibody (YA1174) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CLEC4C.

HY-P81429A

	CLEC4C Antibody (YA1174)(PBS only) CLEC4C; BDCA2, CLECSF11, CLECSF7, DLEC, HECL; UNQ9361/PRO34150; C-type lectin domain family 4 member C; CD303; Blood dendritic cell antigen 2 (BDCA-2); C-type lectin superfamily member 7; Dendritic lectin	IHC-P	Human
	CLEC4C Antibody (YA1174) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CLEC4C.

HY-P86350

	Macrophage mannose receptor 1 Antibody (YA6042) 1 Publications Verification MRC1; CLEC13D; CLEC13DL; MRC1L1; Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD206	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Macrophage mannose receptor 1 Antibody (YA6042) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Macrophage mannose receptor 1.

HY-P84974

	Macrophage mannose receptor 1 Antibody (YA4666) MRC1; CLEC13D; CLEC13DL; MRC1L1; Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD206	ELISA	Human
	Macrophage mannose receptor 1 Antibody (YA4666) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Macrophage mannose receptor 1.

HY-P84992

	CLEC12A Antibody (YA4684) CLL1; MICL; CLL-1; DCAL-2; C-type lectin domain family 12 member A; CD371; CD371 nanobody;	ELISA	Human
	CLEC12A Antibody (YA4684) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CLEC12A.

HY-P84969

	CD161 Antibody (YA4661) KLRB1; CLEC5B; NKRP1A; Killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; HNKR-P1a; NKR-P1A; Natural killer cell surface protein P1A; CD161
	CD161 Antibody (YA4661) is a non-conjugated antibody, targeting to CD161.

HY-P81214

	Macrophage mannose receptor 1 Antibody (YA3531) 1 Publications Verification Mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_HUMAN; Macrophage mannose receptor 1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1.	WB	Human, Rat
	Macrophage mannose receptor 1 Antibody (YA3531) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Macrophage mannose receptor 1.

HY-P81214A

	Macrophage mannose receptor 1 Antibody (YA3531)(PBS only) Mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_HUMAN; Macrophage mannose receptor 1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1.	WB	Human, Rat
	Macrophage mannose receptor 1 Antibody (YA3531) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Macrophage mannose receptor 1.

HY-P83614

	CD209 Antibody (YA3359) CD209; CLEC4L; CD209 antigen; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD209	WB	Human
	CD209 Antibody (YA3359) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD209.

HY-P85004

	CD69 Antibody (YA4696) CD69; CLEC2C; Early activation antigen CD69; Activation inducer molecule; AIM; BL-AC/P26; C-type lectin domain family 2 member C; EA1; Early T-cell activation antigen p60; GP32/28; Leukocyte surface antigen Leu-23; MLR-3; CD antigen CD69; CD69 nanobody;	ELISA	Human
	CD69 Antibody (YA4696) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD69.

HY-P84977

	CD23 Antibody (YA4669) Blast 2 antibody; BLAST-2 antibody; Blast2 antibody; C type lectin domain family 4 member J antibody; C-type lectin domain family 4 antibody; C-type lectin domain family 4 member J antibody; C-type lectin domain family 4; member J antibody; CD 23 antibody; CD 23A antibody; CD23 antibody; CD23 antigen antibody; CD23A antibody; CLEC 4J antibody; CLEC4J antibody; Fc epsilon receptor II antibody; Fc epsilon RII antibody; Fc fragment of IgE antibody; Fc fragment of IgE low affinity II receptor for antibody; Fc fragment of IgE receptor II antibody; Fc fragment of IgE; low affinity II; receptor for; CD23; antibody; Fc of IgE antibody; Fc of IgE; low affinity II; receptor for; CD23; antibody; Fc receptor IgE low affinity II alpha polypeptide antibody; Fc receptor; IgE; low affinity II; alpha polypeptide; isoform CRA_a antibody; Fc-epsilon-RII antibody; FCE 2 antibody; FCE2 antibody; FCER 2 antibody; Fcer2 antibody; FCER2_HUMAN antibody; FCER2A antibody; FceRII antibody; IgE binding factor antibody; IgE receptor lymphocyte antibody; IgE-binding factor antibody; IGEBF antibody; Immunoglobulin E binding factor antibody; Immunoglobulin E receptor antibody; Immunoglobulin E receptor; low affinity II antibody; Immunoglobulin E-binding factor antibody; Immunoglobulin epsilon chain antibody; LEUKOCYTE ANTIGEN CD23 antibody; Low Affinity IgE Receptor antibody; Low affinity immunoglobulin epsilon Fc receptor antibody; Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody; Low affinity immunoglobulin epsilon Fc receptor soluble form antibody; Ly-42 antibody; Ly42 antibody; Lymphocyte antigen CD23 antibody; Lymphocyte IgE receptor antibody; MGC93219 antibody; CD23 nanobody;	ELISA, FC	Human
	CD23 Antibody (YA4669) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD23.

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