Macrophage mannose receptor 1 Antibody (YA6042)

(Synonyms: MRC1; CLEC13D; CLEC13DL; MRC1L1; Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD206)
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Based on 1 publication(s) in Google Scholar

Macrophage mannose receptor 1 Antibody (YA6042) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Macrophage mannose receptor 1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, ICC/IF, IP, ELISA

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Conjugation:
    Non-conjugated

Publications Citing Use of MedChemExpress (MCE) Macrophage mannose receptor 1 Antibody (YA6042)

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Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:200-1:1000 1:5000-1:20000 1:200-1:1000 1:5000-1:20000 1:50-1:200

Product Details

Description

Macrophage mannose receptor 1 Antibody (YA6042) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Macrophage mannose receptor 1.

  • Host Rabbit
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 190 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 166 kDa
Purification

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3719126

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human tonsil tissue using Macrophage mannose receptor 1 Antibody (YA6042). The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P86350, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human colon tissue using Macrophage mannose receptor 1 Antibody (YA6042). The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P86350, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human appendix tissue using Macrophage mannose receptor 1 Antibody (YA6042). The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P86350, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human spleen tissue using Macrophage mannose receptor 1 Antibody (YA6042). The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P86350, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human lymph node tissue using Macrophage mannose receptor 1 Antibody (YA6042). The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P86350, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human liver tissue using Macrophage mannose receptor 1 Antibody (YA6042). The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P86350, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human lung tissue using Macrophage mannose receptor 1 Antibody (YA6042). The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P86350, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human lung tissue using Macrophage mannose receptor 1 Antibody (HY-P86350, 1/500). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human kidney tissue using Macrophage mannose receptor 1 Antibody (HY-P86350, 1/500). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human testis tissue using Macrophage mannose receptor 1 Antibody (HY-P86350, 1/500). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded human colon tissue using Macrophage mannose receptor 1 Antibody (HY-P86350, 1/500). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded mouse lung tissue using Macrophage mannose receptor 1 Antibody (HY-P86350, 1/500). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA6042)
    Immunohistochemical analysis of paraffin-embedded mouse testis tissue using Macrophage mannose receptor 1 Antibody (HY-P86350, 1/500). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Background

  • Function

    Macrophage mannose receptor 1 mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains; (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens; (Microbial infection) Acts as a receptor for Dengue virus envelope protein E; (Microbial infection) Interacts with Hepatitis B virus envelope protein

  • Subcellular Localization

    Endosome membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein

  • Isoforms & Post-Translational Modification

    P22897 has 2 isomers: P22897-1: 166012 Da (predicted); P22897-2: 56554 Da (predicted).

  • Subunit

    (Microbial infection) Interacts with Dengue virus

  • SwissProt ID

    P22897

  • Gene ID
  • Synonyms

    MRC1; CLEC13D; CLEC13DL; MRC1L1; Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD206

Macrophage mannose receptor 1 Antibody (YA6042) Related Classifications

MOQ
Minimum order quantity
100 mg

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