CLEC4F/CLECSF13 Protein, Mouse (HEK293, Fc)

CLEC4F/CLECSF13 protein, a receptor with a distinct affinity for galactose and fucose, suggests involvement in endocytosis. With a binding preference for these carbohydrates, it plays a role in recognizing and potentially internalizing cellular components. CLEC4F/CLECSF13's implication in endocytosis highlights its significance in cellular uptake mechanisms, hinting at potential contributions to various physiological processes. CLEC4F/CLECSF13 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC4F/CLECSF13 protein, expressed by HEK293 , with N-hFc labeled tag.

The CLEC4F/CLECSF13 protein functions as a receptor with a specific affinity for galactose and fucose, suggesting its potential involvement in endocytosis. This protein exhibits a binding preference for these carbohydrate molecules, indicating its role in recognizing and potentially internalizing cellular components. The implication of CLEC4F/CLECSF13 in endocytosis underscores its significance in cellular uptake mechanisms, hinting at its potential contributions to various physiological processes.

Measured by its ability to bind fluorescein-conjugated S.aureus Bioparticles. The ED₅₀ for this effect is 2.472 μg/mL, corresponding to a specific activity is 404.531 U/mg.

Mouse

HEK293

N-hFc

P70194 (R70-G548)

51811  [NCBI]

Extracellular Domain

RPEWNKEPPSLLLRGSNNSGHDNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSANDLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVNGQMKDASRELQTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQATKALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQNWKYFNGNFYYFSRDKKPWREAEKFCTSQGAHLASVTSQEEQAFLVQTTSSGDHWIGLTDQGTEGIWRWVDGTPFNNAQSKGFWGKNQPDNWRHRNGEREDCVHVRQQWNDMACGSSYPWVCKKSTGWSAARVG

Approximately 95-120 kDa due to the glycosylation.

• 
  ≥ 90%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.