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OCIL/CLEC2D Protein, Rat (HEK293, Fc)

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The OCIL/CLEC2D protein, also known as osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor located on the cell surface. Lectins are proteins that specifically bind to carbohydrates, and OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes by acting as a lectin-type receptor. OCIL/CLEC2D Protein, Rat (HEK293, Fc) is the recombinant rat-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc labeled tag.

For research use only. We do not sell to patients.
  • Species: Rat
  • Source: HEK293
  • Storage:
    Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
  • OCIL/CLEC2D Protein, Rat (HEK293, Fc) Product Image
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
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Biological Activity

Description

The OCIL/CLEC2D protein, also known as osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor located on the cell surface. Lectins are proteins that specifically bind to carbohydrates, and OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes by acting as a lectin-type receptor. OCIL/CLEC2D Protein, Rat (HEK293, Fc) is the recombinant rat-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc labeled tag.

Background

OCIL/CLEC2D protein, also known as Osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor that is located on the cell surface. Lectins are proteins that bind specifically to carbohydrates, and by operating as a lectin-type receptor, OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes. Based on its classification as a lectin-type receptor, it is likely involved in mediating cellular interactions, adhesion, or immune responses through the recognition of specific carbohydrate molecules. Further investigation is needed to fully understand the biological significance and molecular mechanisms of OCIL/CLEC2D protein.

Verified Bioactivity

Measured by its binding ability in a functional ELISA. Immobilized Human CD161, at 10μg/mL (100 μL/well) can bind Rat OCIL. The ED50 for this effect is 3.446 μg/mL.

Technical Parameters

  • Species Rat
  • Source HEK293
  • Tag N-hFc
  • Accession

    Q925N7 (K98-L233)

  • Gene ID
    113937  [NCBI]
  • Molecular Construction
    • N-term
    • hFc
    • OCIL (K98-L233)
      Accession # Q925N7
    • C-term
  • Protein Length

    Extracellular Domain

  • Synonyms

    CLEC2D; C-Type Lectin Domain Family 2 Member D Isoform 11; C-Type Lectin Domain Family 2 Member D; C-Type Lectin Domain Family 2 Member D Isoform 12; LLT1; C-Type Lectin Domain Family 2 Member D Variant 2; CLAX; C-Type Lectin Domain Family 2 Member D Vari

  • AA Sequence

    KKTAQISTINTYAACPRNWIGVGNKCFYFNEIPSNWTLSQTLCKEQGAELARFDTEEELNFLRRYKGSSGYWFGLHRESSAHPWKWTDNTEYNNSVSIGGDEKHGFLSDNGFSSGRGYIVRKSICRKPNSYTSQCL

  • Molecular Weight

    Approximately 44-54 kDa & 36 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • OCIL/CLEC2D Protein, Rat (HEK293, Fc) Product Image
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  • OCIL/CLEC2D Protein, Rat (HEK293, Fc) Product Image