PNU-159682 carboxylic acid

Cat. No.: HY-126666 Purity: 92.02%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

PNU-159682 carboxylic acid (compound 53) is a potent ADCs cytotoxin and encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. PNU-159682 carboxylic acid has protein fold and diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response.

For research use only. We do not sell to patients.

PNU-159682 carboxylic acid Chemical Structure

CAS No. : 1204819-92-0

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 3038	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 3038	In-stock	Estimated Time of Arrival: December 31
Solid
1 mg	USD 750	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 2200	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 3650	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

Daunorubicins/Doxorubicins

Molecular Weight

627.59

Formula

C₃₁H₃₃NO₁₃

CAS No.

1204819-92-0

Appearance

Solid

Color

Brown to red

SMILES

C[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(O)=O)(O)C4)C(O)=C6C(C(C7=C(OC)C=CC=C7C6=O)=O)=C5O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (79.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5934 mL	7.9670 mL	15.9340 mL
5 mM	0.3187 mL	1.5934 mL	3.1868 mL
10 mM	0.1593 mL	0.7967 mL	1.5934 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 92.02%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (257 KB) HNMR (318 KB) RP-HPLC (284 KB) LCMS (100 KB)

Handling Instructions (2659 KB)

References

[1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5934 mL	7.9670 mL	15.9340 mL	39.8349 mL
	5 mM	0.3187 mL	1.5934 mL	3.1868 mL	7.9670 mL
	10 mM	0.1593 mL	0.7967 mL	1.5934 mL	3.9835 mL
	15 mM	0.1062 mL	0.5311 mL	1.0623 mL	2.6557 mL
	20 mM	0.0797 mL	0.3983 mL	0.7967 mL	1.9917 mL
	25 mM	0.0637 mL	0.3187 mL	0.6374 mL	1.5934 mL
	30 mM	0.0531 mL	0.2656 mL	0.5311 mL	1.3278 mL
	40 mM	0.0398 mL	0.1992 mL	0.3983 mL	0.9959 mL
	50 mM	0.0319 mL	0.1593 mL	0.3187 mL	0.7967 mL
	60 mM	0.0266 mL	0.1328 mL	0.2656 mL	0.6639 mL