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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
431 Results for "
long chain
" in MedChemExpress (MCE) Product Catalog:
Products (431)
431 Results for "long chain" in MCE Product Catalog:
120
116
116
65
45
45 Cited Publications
Referencia número: HY-112847A
Pureza: ≥98.0%
Synonyms: Sulfo-N-succinimidyl oleate sodium
Target:
Áreas de investigación:
Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect .
45
45 Cited Publications
Referencia número: HY-D1028
No. CAS: 127274-91-3
32
32 Cited Publications
Referencia número: HY-B0660
No. CAS: 10417-94-4
Synonyms: EPA; Timnodonic acid
32
32 Cited Publications
Referencia número: HY-W011269
No. CAS: 73167-03-0
Synonyms: EPA sodium; Timnodonic acid sodium
30
30 Cited Publications
Referencia número: HY-D0969
No. CAS: 34215-57-1
Synonyms: DiOC18(3); 3,3'-Dioctadecyloxacarbocyanine perchlorate
22
22 Cited Publications
Synonyms: (R)-Carnitine; Levocarnitine
Category:
Natural Products Neurological Disease Endocrine diseases Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Disease markers Nervous System Disorder Disease Research Fields Cancer
Target:
22
22 Cited Publications
Synonyms: (R)-Carnitine hydrochloride; Levocarnitine hydrochloride
Target:
22
22 Cited Publications
Referencia número: HY-W105518
No. CAS: 36687-82-8
19
19 Cited Publications
Referencia número: HY-B0968
No. CAS: 13171-25-0
Target:
Áreas de investigación:
Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
19
Target:
Áreas de investigación:
Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
18
18 Cited Publications
Target:
Áreas de investigación:
CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively.
CAY10566 also shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM) .
14
14 Cited Publications
Target:
Áreas de investigación:
TUG-891 is a potent and selective agonist for the long chain free fatty acid (LCFA) receptor 4 (FFA4/GPR120) .
12
Target:
7
7 Cited Publications
5
Target:
Áreas de investigación:
Intralipid 20% is a safe fat emulsion, composed of soybean oil (consisting of a mixture of long-chain triglycerides (C14-24) of predominantly unsaturated fatty acids), and egg phospholipids, can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
