2 Results for "

mGluR family

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "mGluR family" in MCE Product Catalog:

Cat. No.: HY-100838A
CAS No.: 117857-93-9
Target:  

mGluR

Research Areas:  

Metabolic Disease

L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family .
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Cat. No.: HY-L006
3,519 compounds

GPCRs are a large family of cell surface receptors that respond to a variety of external signals. Binding of a signaling molecule to a GPCR results in G protein activation, which in turn triggers the production of any number of second messengers. GPCRs play an important role in the human body, and increased understanding of these receptors has greatly affected modern medicine. In fact, researchers estimate that between one-third to one-half of all approved drugs act by binding to GPCRs. GPCRs are a large group of drug targets in drug discovery.

MCE provides a unique collection of 3,519 small molecules targeting GPCRs that can be used in the screening for various GPCRs-related research and drug development projects.