6 Results for "

mTOR-independent

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "mTOR-independent" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-135825
CAS No.: 39777-61-2
Purity:  99.71%
Target:  

Autophagy

Research Areas:  

Neurological Disease

TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment .
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2
2 Cited Publications
Cat. No.: HY-100200
CAS No.: 307538-42-7
Purity:  99.92%
Target:  

Autophagy

Research Areas:  

Cancer

SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide.
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Cat. No.: HY-P3990
CAS No.: 1029227-48-2
Target:  

VEGFR Autophagy Apoptosis

Research Areas:  

Cancer

Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, shows potent antiproliferative activity. Coibamide A induces autophagosome accumulation via an mTOR-independent mechanism. Coibamide A induces apoptosis. Coibamide A inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts .
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Cat. No.: HY-125197
CAS No.: 2446154-91-0
Target:  

Autophagy

Research Areas:  

Inflammation/Immunology

BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway. BRD5631 affects several cellular disease phenotypes previously linked to autophagy, including protein aggregation, cell survival, bacterial replication, and inflammatory cytokine production .
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Cat. No.: HY-18672
CAS No.: 944153-47-3
Target:  

Autophagy

Research Areas:  

Cancer

SMER18 is a small molecule enhancer of rapamycin which act as a mTOR-independent autophagy inducer.
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Cat. No.: HY-100200R
CAS No.: 307538-42-7
Research Areas:  

Cancer

SMER28 (Standard) is the analytical standard of SMER28 (HY-100200). This product is intended for research and analytical applications. SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide.
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