39777-61-2
Chemical Structure
TFEB activator 1
- CAS No.: 39777-61-2
- Formula:C19H18O3
- Molecular Weight:294.34
IUPAC Name: (1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one
InChIKey: RCZMPCUUTSDNAJ-PHEQNACWSA-N
SMILES: O=C(/C=C/C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2OC
Biological Activity: TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TFEB activator 1 | 99.71% | TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment. | ||||||||||||||||||||
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TFEB activator 1 (Standard) | ≥98% | TFEB activator 1 (Standard) is the analytical standard of TFEB activator 1 (HY-135825). This product is intended for research and analytical applications. TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment. | ||||||||||||||||||||
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Similarity Score 0.80
HY-103667R2-HBA (Standard) -
Similarity Score 0.75
HY-1284522'-Hydroxy-2-methoxychalcone -
Similarity Score 0.73
HY-116117Salicylcurcumin -
Similarity Score 0.71
HY-120914TrxR1-IN-B19 -
Similarity Score 0.71
HY-1643612′-Hydroxy-2,3-dimethoxychalcone -
Similarity Score 0.70
HY-W083373(E)-3,4-Dimethoxychalcone -
Similarity Score 0.70
HY-W083373A3,4-Dimethoxychalcone -
Similarity Score 0.70
HY-75828Dibenzylideneacetone -
Similarity Score 0.70
HY-W012192trans,trans-Dibenzylideneacetone -
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