39777-61-2
Chemical Structure
TFEB activator 1
- CAS No.: 39777-61-2
- Formula:C19H18O3
- Molecular Weight:294.34
IUPAC Name: (1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one
InChIKey: RCZMPCUUTSDNAJ-PHEQNACWSA-N
SMILES: O=C(/C=C/C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2OC
Biological Activity: TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment[1].
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TFEB activator 1 | 99.71% | TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment. | ||||||||||||||||||||
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Keywords