39777-61-2

TFEB activator 1 Chemical Structure
39777-61-2

Chemical Structure

TFEB activator 1

  • CAS No.: 39777-61-2
  • Formula:C19H18O3
  • Molecular Weight:294.34

IUPAC Name: (1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one

InChIKey: RCZMPCUUTSDNAJ-PHEQNACWSA-N

SMILES: O=C(/C=C/C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2OC

Biological Activity: TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment[1].

Cat. No. Product Name Purity Description Pricing
HY-135825
TFEB activator 1 99.71% TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment.
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