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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
metallothionein 1a
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "metallothionein 1a" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-13545
CAS No.: 251579-55-2
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Cat. No.: HY-W101299
CAS No.: 54831-20-8
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Cat. No.: HY-P4910
CAS No.: 1622872-91-6
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Cat. No.: HY-P2120
CAS No.: 79438-64-5
Cat. No.: HY-119578
CAS No.: 72963-72-5
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Imiprothrin is an inducer that induces CYP1A2 and metallothionein 1a, with significant genotoxicity and cytotoxicity. In rat hepatocytes, Imiprothrin initiates detoxification responses by triggering the overexpression of these two genes. Imiprothrin induces chromosomal aberrations and micronucleus formation in rat bone marrow cells, and causes DNA damage in hepatocytes. Imiprothrin triggers oxidative stress in rats, leading to lipid peroxidation, excessive reactive oxygen species production and redox imbalance, which in turn impairs liver and kidney functions and causes tissue damage. Imiprothrin inhibits weight gain in mice, and even causes high mortality in female mice at high doses. However, it shows no carcinogenicity in rat experiments; among relevant indicators, aspartate aminotransferase and total protein are identified as sensitive toxicity biomarkers .
Cat. No.: HY-P3119
CAS No.: 194660-14-5
Synonyms: Desotamide A
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Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).
Cat. No.: HY-P4613
CAS No.: 130674-54-3
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Cat. No.: HY-P11022
CAS No.: 55599-68-3
Synonyms: A-3302-B
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
