194660-14-5
Chemical Structure
Desotamide
Synonym(s): Desotamide A
- CAS No.: 194660-14-5
- Formula:C35H52N8O7
- Molecular Weight:696.84
IUPAC Name: 2-((2S,8S,11S,14R,17S)-8-((1H-indol-3-yl)methyl)-17-((R)-sec-butyl)-11,14-diisobutyl-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexaazacyclooctadecan-2-yl)acetamide
InChIKey: LJGXNPVJAKBNOK-DTWKRICWSA-N
SMILES: O=C(N[C@H](C(N[C@@H](C(N[C@@]1([H])[C@H](C)CC)=O)CC(C)C)=O)CC(C)C)[C@@H](NC(CNC([C@@H](NC1=O)CC(N)=O)=O)=O)CC2=CNC3=CC=CC=C23
Biological Activity: Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).
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Desotamide | Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively). | |||||||||||||||||||||
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