36 Results for "

migraine headache

" in MedChemExpress (MCE) Product Catalog:
Products (36)

36 Results for "migraine headache" in MCE Product Catalog:

69
69 Publications Verification
Cat. No.: HY-10585
CAS No.: 99-66-1
Purity:  99.19%
Synonyms: VPA; 2-Propylpentanoic acid; Dipropylacetic acid
Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM. Valproic acid inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .
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69
69 Publications Verification
Cat. No.: HY-10585A
CAS No.: 1069-66-5
Purity:  98.14%
Synonyms: Sodium Valproate; VPA sodium; 2-Propylpentanoic acid sodium
Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .
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7
7 Cited Publications
Cat. No.: HY-B0121B
CAS No.: 103628-46-2
Synonyms: GR 43175 free base
Target:  

5-HT Receptor

Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan can be used for migraine headache research .
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7
7 Cited Publications
Cat. No.: HY-B0121
CAS No.: 103628-48-4
Synonyms: GR 43175 succinate
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan succinate can be used for migraine headache research .
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1
1 Cited Publications
Cat. No.: HY-P99021
CAS No.: 1578199-75-3
Synonyms: LY 2951742
Galcanezumab (LY 2951742) is a humanized IgG4 monoclonal antibody against the CGRP ligand. Galcanezumab can be used for migraine or cluster headaches research .
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1
1 Cited Publications
Cat. No.: HY-10585S
CAS No.: 87745-17-3
Purity:  ≥98.0%
Synonyms: VPA-d4; 2-Propylpentanoic acid-d4
Valproic acid-d4 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches .
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1
1 Cited Publications
Cat. No.: HY-B0121BS
CAS No.: 1215621-31-0
Synonyms: GR 43175C-d6
Sumatriptan-d6 succinate is the deuterium labeled Sumatriptan succinate. Sumatriptan succinate is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for migraine headache research .
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Cat. No.: HY-10585S1
CAS No.: 87745-18-4
Purity:  98.71%
Synonyms: VPA-d6; 2-Propylpentanoic acid-d6
Valproic acid-d6 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches .
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Cat. No.: HY-78509
CAS No.: 1210-35-1
Dibenzosuberone is a tricyclic compound, commonly referred to as a tricyclic antidepressant (TCA), and is widely used in research on migraine, tension-type headache, anxiety disorder and schizophrenia. Dibenzosuberone also serves as a key intermediate for the synthesis of various active pharmaceutical ingredients (APIs) (e.g., amitriptyline (HY-B0527), nortriptyline (HY-118620), nortriptyline or cyproheptadine (HY-B1622)) .
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Cat. No.: HY-10585S2
CAS No.: 362049-65-8
Purity:  ≥99.0%
Synonyms: VPA-d15; 2-Propylpentanoic acid-d15
Valproic acid-d15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches .
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Cat. No.: HY-10585B
CAS No.: 76584-70-8
Synonyms: Sodium Valproate (2:1); VPA sodium (2:1); 2-Propylpentanoic acid sodium (2:1)
Valproic acid (VPA) sodium (2:1) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium (2:1) activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium (2:1) is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .
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Cat. No.: HY-10585AR
CAS No.: 1069-66-5
Synonyms: Sodium Valproate (Standard); VPA sodium (Standard); 2-Propylpentanoic acid sodium (Standard)
Valproic acid (sodium) (Standard) is the analytical standard of Valproic acid (sodium). This product is intended for research and analytical applications. Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .
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Cat. No.: HY-10585S4
CAS No.: 345909-03-7
Synonyms: VPA-d4-1; 2-Propylpentanoic acid-d4-1
Valproic acid-d4-1 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches .
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Cat. No.: HY-130579
CAS No.: 728944-69-2
Purity:  ≥95.0%
Synonyms: L-VNIO hydrochloride
Vinyl-L-NIO (L-VNIO) hydrochloride is a neuronal nitric oxide synthase (NOS) inhibitor with a rat Ki of 0.10 μM. Vinyl-L-NIO hydrochloride inhibits NADPH oxidase activity, attenuates renal fibrosis, inflammation, oxidative stress indices, and albuminuria. Vinyl-L-NIO hydrochloride can be used for the research of parkinson's disease, migraine headache, and hypertension .
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Cat. No.: HY-123442
CAS No.: 188400-51-3
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

L 775,606 is a potent and selective 5-HT1D receptor agonist. L 775,606 can be used to study migraine headache .
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Cat. No.: HY-B0121R
CAS No.: 103628-48-4
Synonyms: GR 43175 succinate (Standard)
Research Areas:  

Neurological Disease

Sumatriptan (succinate) (Standard) is the analytical standard of Sumatriptan (succinate). This product is intended for research and analytical applications. Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for migraine headache research .
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Cat. No.: HY-B0121BR
CAS No.: 103628-46-2
Synonyms: GR 43175 free base (Standard)
Research Areas:  

Neurological Disease

Sumatriptan (Standard) is the analytical standard of Sumatriptan. This product is intended for research and analytical applications. Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan can be used for migraine headache research .
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Cat. No.: HY-10585AG
CAS No.: 1069-66-5
Synonyms: Sodium Valproate (GMP); VPA sodium (GMP); 2-Propylpentanoic acid sodium (GMP)
Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .
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Cat. No.: HY-W794759
CAS No.: 62959-43-7
Synonyms: Magnesium valproate; VPA magnesium; 2-Propylpentanoic acid magnesium
Valproic acid magnesium (Magnesium valproate) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM. Valproic acid magnesium inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid magnesium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid magnesium is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .
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Cat. No.: HY-106736
CAS No.: 42145-91-5
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Etilefrine pivalate hydrochloride is an orally active compound and can be used for study of migraine headaches .
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