5 Results for "

multidrug-resistant K1 strain

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "multidrug-resistant K1 strain" in MCE Product Catalog:

Cat. No.: HY-N5109
CAS No.: 138664-32-1
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively .
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Cat. No.: HY-N2380
CAS No.: 132201-33-3
N-Benzoyl-(2R,3S)-3-phenylisoserine is the C-13 chiral side chain of paclitaxel and serves as a synthetic scaffold for constructing paclitaxel and related hybrid molecules. N-Benzoyl-(2R,3S)-3-phenylisoserine is used in studies on paclitaxel side chain synthesis and the design of anti-Plasmodium hybrid molecules .
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Cat. No.: HY-170219
CAS No.: 3113265-82-7
Research Areas:  

Infection

RMM23 is an inhibitor targeting PfBDP1 with a Kd value of 1.24 μM. RMM23 against the wild-type strains 3D7 and NF54, and the multidrug-resistant K1 strain in vitro blood stage, with EC50 values of 18 μM, 14 μM, 20 μM, respectively .
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Cat. No.: HY-126640
CAS No.: 359844-69-2
Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively .
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Cat. No.: HY-137985
CAS No.: 149598-70-9
Synonyms: Stachybotrydial; F 1839M; Stachybotrydial
Target:  

HSV Virus Protease

Research Areas:  

Infection

Mer-NF5003F (Stachybotrydial; F 1839M), a sesquiterpene isolated from Stachybotrys, inhibits avian medulloblastoma virus (AMV) protease (IC50=7.8 μM). Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50=0.61, 6.7, and 10 μg/mL, respectively), and fucosyltransferase (IC50=11.3 μg/mL). Mer-NF5003F has in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 μg/mL) and multidrug-resistant Plasmodium falciparum K1 strain (IC50=0.85 μg/mL).
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